[Hub]/) : Traits : Birth weight : ← →

chr7:2,032,803-3,581,391

Best TWAS P=1.48e-13 · Best GWAS P=1.12e-13 conditioned to 0.128

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Esophagus Mucosa	GNA12	0.16	0.13	lasso	3	0.13	3.0e-09	-7.3	-7.4	1.5e-13	0.93	0.01	0.99	TRUE
13	GTEx	Skin Sun Exposed Lower leg	GNA12	0.17	0.16	lasso	3	0.18	1.3e-14	-6.7	-7.3	2.2e-13	0.85	0.18	0.82	FALSE
4	GTEx	Cells Transformed fibroblasts	GNA12	0.21	0.11	lasso	11	0.15	1.7e-11	-7.2	-7.3	3.3e-13	0.87	0.01	0.99	FALSE
11	GTEx	Nerve Tibial	GNA12	0.31	0.34	lasso	7	0.36	9.6e-27	-6.3	-7.1	1.3e-12	0.83	0.68	0.32	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	AMZ1	0.32	0.04	enet	19	0.20	3.3e-19	-7.0	7.0	1.8e-12	-0.57	0.06	0.94	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	GNA12	0.20	0.12	lasso	6	0.12	3.4e-05	-6.5	-7.0	1.9e-12	0.82	0.05	0.93	FALSE
9	GTEx	Esophagus Muscularis	GNA12	0.32	0.31	lasso	3	0.34	2.1e-21	-7.1	-7.0	3.5e-12	0.93	0.02	0.98	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	GNA12	0.10	0.15	lasso	3	0.12	4.2e-07	6.6	-6.9	4.6e-12	0.55	0.26	0.72	FALSE
16	GTEx	Whole Blood	GNA12	0.09	0.01	enet	4	0.00	3.3e-01	-7.0	-6.9	6.3e-12	0.90	0.03	0.90	FALSE
14	GTEx	Small Intestine Terminal Ileum	GNA12	0.34	0.20	lasso	5	0.16	2.4e-04	-6.5	-6.8	7.7e-12	0.74	0.09	0.71	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	GNA12	0.46	0.51	lasso	5	0.50	7.9e-19	-6.7	-6.8	1.2e-11	0.90	0.33	0.67	FALSE
17	METSIM	Adipose	GNA12	0.07	0.05	lasso	3	0.05	3.3e-08	-6.5	-6.6	4.0e-11	0.75	0.33	0.67	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GNA12	0.03	0.04	lasso	1	0.04	3.0e-05	-6.5	-6.5	6.7e-11	0.68	0.08	0.78	FALSE
2	GTEx	Artery Tibial	GNA12	0.24	0.13	enet	20	0.22	3.5e-17	-7.1	-6.5	7.0e-11	0.86	0.02	0.98	FALSE
1	GTEx	Adipose Subcutaneous	GNA12	0.11	0.08	lasso	4	0.07	1.3e-06	-6.5	-6.4	1.3e-10	0.72	0.48	0.52	FALSE
15	GTEx	Stomach	GNA12	0.18	0.16	lasso	2	0.13	6.6e-07	-6.3	-6.2	4.5e-10	0.68	0.47	0.52	FALSE
5	GTEx	Colon Sigmoid	GNA12	0.14	0.05	lasso	3	0.03	3.6e-02	-6.3	-6.2	7.2e-10	0.82	0.05	0.82	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	AMZ1	0.09	0.05	lasso	6	0.04	2.4e-06	-7.1	5.8	5.2e-09	-0.89	0.02	0.98	FALSE
10	GTEx	Lung	GNA12	0.16	0.08	enet	21	0.12	1.2e-09	-7.3	-5.8	8.5e-09	0.78	0.01	0.99	FALSE
6	GTEx	Colon Transverse	GNA12	0.19	0.08	lasso	4	0.10	2.3e-05	4.8	-5.7	1.3e-08	0.62	0.19	0.80	FALSE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	AMZ1	0.08	0.01	blup	71	0.05	1.3e-05	-6.5	5.4	5.3e-08	-0.66	0.03	0.87	FALSE
21	The Cancer Genome Atlas	Lung Adenocarcinoma	GNA12	0.03	0.01	enet	7	0.02	1.5e-03	2.7	-5.4	7.0e-08	0.76	0.05	0.77	FALSE
19	The Cancer Genome Atlas	Esophageal Carcinoma	AMZ1	0.18	0.05	blup	69	0.05	1.4e-02	3.7	-5.2	2.3e-07	0.75	0.01	0.64	FALSE