TWAS
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About
Usage
Models
Genes
Traits
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Traits
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Birth weight
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chr7:22,946,782-24,382,726
Best TWAS P=2.53e-11 · Best GWAS P=9.12e-20 conditioned to 2.22e-07
23M
23.2M
23.4M
23.6M
23.8M
24M
24.2M
24.4M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Mucosa
CCDC126
0.12
0.03
lasso
7
0.01
0.043
-7.1
6.7
2.5e-11
-0.66
0.06
0.68
TRUE
2
The Cancer Genome Atlas
Esophageal Carcinoma
TRA2A
0.18
0.02
blup
40
0.05
0.012
-8.2
-6.6
3.7e-11
0.64
0.00
0.59
TRUE
3
The Cancer Genome Atlas
Soft Tissue Sarcoma
RPS2P32
0.08
0.02
blup
27
0.02
0.031
-5.4
6.2
5.6e-10
-0.70
0.02
0.43
FALSE