Best TWAS P=2.58e-10 · Best GWAS P=1.41e-12 conditioned to 0.116
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | TNNT3 | 0.21 | -0.01 | enet | 17 | 0.00 | 6.4e-01 | -0.38 | 5.9 | 2.9e-09 | 0.16 | 0.03 | 0.30 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C11orf21 | 0.08 | 0.05 | blup | 65 | 0.06 | 6.0e-07 | -2.33 | -5.2 | 2.5e-07 | -0.10 | 0.91 | 0.04 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | IGF2 | 0.06 | 0.00 | blup | 58 | 0.01 | 2.7e-02 | 6.53 | 6.3 | 2.6e-10 | 0.72 | 0.01 | 0.57 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | TSPAN32 | 0.05 | 0.00 | blup | 69 | 0.02 | 8.5e-03 | -3.74 | -5.2 | 2.6e-07 | -0.10 | 0.02 | 0.11 | FALSE |