Best TWAS P=1.59e-09 · Best GWAS P=6.46e-07 conditioned to 0.906
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | NRBF2 | 0.06 | 0.01 | lasso | 3 | 0.00 | 4.0e-01 | -5.0 | 6.0 | 1.6e-09 | -0.81 | 0.03 | 0.34 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | ADO | 0.06 | 0.04 | lasso | 2 | 0.06 | 3.1e-08 | -4.9 | 5.2 | 1.7e-07 | -0.83 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ADO | 0.14 | 0.05 | blup | 53 | 0.05 | 3.8e-06 | -5.0 | 5.2 | 2.3e-07 | -0.82 | 0.00 | 0.99 | FALSE |