Best TWAS P=1.34e-08 · Best GWAS P=7.32e-10 conditioned to 0.00845
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | SDK1 | 0.18 | 0.12 | lasso | 8 | 0.14 | 9.4e-12 | -5.5 | 5.5 | 3.4e-08 | 0.88 | 0.10 | 0.90 | FALSE |
| 2 | GTEx | Esophagus Muscularis | SDK1 | 0.08 | 0.03 | lasso | 5 | 0.02 | 1.1e-02 | -5.9 | 5.6 | 2.1e-08 | 0.80 | 0.11 | 0.86 | FALSE |
| 3 | GTEx | Muscle Skeletal | SDK1 | 0.13 | 0.02 | lasso | 4 | 0.03 | 1.4e-03 | -5.5 | 5.7 | 1.3e-08 | 0.82 | 0.11 | 0.89 | TRUE |
| 4 | METSIM | Adipose | SDK1 | 0.09 | 0.07 | lasso | 15 | 0.11 | 3.9e-16 | 6.1 | 5.4 | 8.1e-08 | 0.82 | 0.01 | 0.99 | FALSE |