TWAS hub - SDK1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0950	0.0270	2.2e-05	0.033	0.037	0.029	0.039	0.040	6.2e-05	2.6e-05	1.5e-04	1.5e-05	1.0e-05
2	GTEx	Adipose Subcutaneous	0.1800	0.0420	7.8e-09	0.123	NA	0.141	NA	0.143	3.2e-10	NA	1.3e-11	NA	9.4e-12
3	GTEx	Adipose Visceral Omentum	0.1860	0.0680	1.5e-03	0.076	NA	0.051	NA	0.100	8.9e-05	NA	1.2e-03	NA	7.2e-06
4	GTEx	Artery Coronary	0.2890	0.1010	9.0e-03	0.019	NA	0.100	NA	0.106	7.2e-02	NA	3.0e-04	NA	1.9e-04
5	GTEx	Artery Tibial	0.1304	0.0492	1.4e-03	0.006	NA	-0.001	NA	0.009	9.9e-02	NA	3.8e-01	NA	5.5e-02
6	GTEx	Cells Transformed fibroblasts	0.1690	0.0410	1.6e-06	0.118	NA	0.102	NA	0.109	3.9e-09	NA	4.6e-08	NA	1.5e-08
7	GTEx	Esophagus Muscularis	0.0830	0.0360	9.9e-03	0.035	NA	0.013	NA	0.025	3.5e-03	NA	5.3e-02	NA	1.1e-02
8	GTEx	Heart Atrial Appendage	0.2160	0.0890	8.3e-03	-0.005	NA	-0.006	NA	0.008	6.4e-01	NA	7.3e-01	NA	1.4e-01
9	GTEx	Heart Left Ventricle	0.3536	0.0755	1.3e-05	0.189	NA	0.208	NA	0.200	2.5e-10	NA	2.5e-11	NA	6.3e-11
10	GTEx	Lung	0.1041	0.0448	2.2e-03	0.004	NA	0.002	NA	0.000	1.4e-01	NA	2.3e-01	NA	3.3e-01
11	GTEx	Muscle Skeletal	0.1310	0.0380	7.8e-06	0.016	NA	0.025	NA	0.025	8.8e-03	NA	1.5e-03	NA	1.4e-03
12	GTEx	Pancreas	0.2250	0.0830	9.0e-03	-0.006	NA	-0.006	NA	-0.006	6.8e-01	NA	7.1e-01	NA	7.8e-01
13	GTEx	Skin Sun Exposed Lower leg	0.2070	0.0460	6.5e-09	0.048	NA	0.121	NA	0.117	7.8e-05	NA	3.0e-10	NA	6.6e-10
14	GTEx	Vagina	0.6380	0.1340	6.8e-03	0.011	NA	-0.012	NA	0.027	1.8e-01	NA	7.9e-01	NA	8.0e-02
15	GTEx	Whole Blood	0.1590	0.0420	1.2e-05	0.081	NA	0.107	NA	0.107	5.8e-08	NA	4.6e-10	NA	4.4e-10
16	METSIM	Adipose	0.0866	0.0201	8.3e-12	0.071	0.097	0.108	0.101	0.110	8.0e-11	2.2e-14	8.5e-16	7.1e-15	3.9e-16
17	ROSMAP	Brain Pre-frontal Cortex	0.0678	0.0321	1.7e-02	0.000	0.019	-0.002	0.019	-0.002	3.3e-01	1.3e-03	8.5e-01	1.4e-03	8.7e-01
18	TCGA	Breast Invasive Carcinoma	0.0223	0.0107	3.5e-03	0.001	0.010	0.004	NA	0.001	1.5e-01	3.3e-03	5.2e-02	NA	1.6e-01
19	TCGA	Kidney Renal Clear Cell Carcinoma	0.0603	0.0332	8.3e-03	0.006	0.016	0.022	NA	0.002	6.8e-02	6.2e-03	1.3e-03	NA	1.6e-01
20	TCGA	Brain Lower Grade Glioma	0.0758	0.0379	4.8e-03	0.013	0.016	0.053	NA	0.038	1.1e-02	5.5e-03	1.2e-06	NA	3.2e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	13	14	15	16	17	18	19	20
Smoking status: Previous	7.6	11.4	32.3	-1.2	5.5	3.2	0.7	-4.2	-4.1	5.6	3.4	0.4	0.6	5.7	3.3	-0.7	0.9	5.4	0.3	4.5	1.4	3.2
Past tobacco smoking	6.5	11.9	38.9	1.6	-5.7	-2.8	-1.1	4.7	4.6	-6.2	-3.1	0.1	-0.2	-5.7	-3.0	1.5	-0.4	-5.4	-0.3	-4.4	-1.9	-2.4
Forced expiratory volume in 1-second (FEV1), predicted	4.8	9.9	31.9	2.5	3.7	3.1	-0.0	-2.8	-4.3	3.8	5.6	3.5	2.2	3.6	3.1	0.2	3.2	3.7	3.5	3.1	2.7	1.9
Smoking Status	4.6	10.9	33.3	-4.1	5.2	2.6	-0.0	-4.2	-3.9	5.8	1.7	-1.0	0.2	5.5	3.0	-1.4	-0.9	5.0	-1.4	4.3	1.8	2.8
Qualifications: NVQ or HND or HNC or equivalent	4.6	5.5	14.5	0.3	3.5	2.4	-0.4	-3.1	-3.1	3.6	1.8	-0.7	0.5	3.5	2.4	-0.5	0.7	3.8	0.7	3.0	1.7	3.0
Ever smoked	4.4	7.7	27.8	-1.1	4.6	2.0	1.0	-4.1	-3.7	5.3	2.3	0.0	-0.4	4.5	2.3	-1.5	-0.6	4.4	0.7	3.1	1.9	1.2
Taking other prescription medications	3.9	5.9	17.4	-4.2	-2.1	-2.9	-3.2	-0.0	2.2	-1.4	-2.3	-3.0	-3.3	-1.6	-2.6	0.2	-3.7	-2.5	-3.1	-2.3	-1.6	-0.4
Respiratory disease	3.4	7.6	23.1	-4.6	-0.5	-3.2	-4.7	-2.0	1.0	0.3	-2.7	-4.4	-4.3	0.2	-1.6	-0.5	-4.8	-1.9	-2.2	-2.2	-2.8	-0.1
Happiness	3.4	4.2	17.0	-1.1	-2.6	-4.1	-2.8	0.4	1.9	-1.6	-2.0	-1.7	-0.3	-1.6	-1.9	0.4	-3.6	-2.8	-2.3	-1.8	-0.9	-0.7
Breast cancer (self-reported)	3.3	4.0	10.2	0.3	-2.7	-3.1	-1.1	0.7	2.3	-2.3	-1.6	-0.7	-1.8	-2.6	-2.8	-0.4	-2.2	-3.2	0.5	-3.1	-2.0	-1.2
Qualifications: nursing, teaching	3.2	5.0	14.5	-0.4	-3.7	-1.9	-0.8	3.8	3.0	-3.6	-0.6	-1.7	-0.5	-3.6	-1.6	-1.4	-1.2	-2.7	-2.1	-1.7	-2.5	-1.5
Maternal smoking around birth	3.1	4.5	17.5	-1.3	3.8	1.6	1.4	-3.3	-1.7	3.5	0.2	0.4	-0.3	4.2	2.7	-0.0	0.4	2.8	-0.1	2.2	1.9	1.4
Had other major operations	3.1	3.7	11.2	0.0	-2.8	-0.7	-2.2	2.0	0.9	-2.0	-2.5	-2.0	-2.6	-3.3	-2.5	-1.1	-0.7	-2.9	-0.2	-1.9	-0.9	-2.1
Qualifications: College or University degree	2.8	8.7	25.4	4.5	-4.0	-1.0	1.7	4.7	2.5	-4.1	-0.2	1.8	0.3	-5.0	-2.6	0.6	1.3	-3.5	3.4	-3.6	-1.9	-3.1
Ovarian Cancer	2.7	3.6	13.5	-0.2	-1.7	-2.0	-1.4	0.5	0.2	-0.9	-3.0	-3.7	-3.1	-1.9	-2.2	0.8	-1.6	-2.5	-0.3	-1.6	-1.2	-2.5
Body Mass Index (BMI) (2010)	2.6	3.5	10.9	-1.8	-2.5	-2.1	-2.3	1.6	2.6	-2.8	-0.5	-0.1	-2.1	-1.8	-1.2	0.2	-1.8	-2.3	-3.3	-1.5	-2.0	0.3
Bipolar Disorder (2011)	2.5	2.4	6.8	-1.7	-1.6	-2.3	-2.2	-0.3	0.9	-0.8	-0.6	0.3	-2.5	-1.3	-2.3	0.1	-2.6	-1.8	-1.7	-1.3	-1.6	-0.7
Frequency of tiredness / lethargy in last 2 weeks	2.5	4.0	16.2	-4.0	-0.7	-2.5	-2.6	-1.3	1.3	-0.5	-1.9	-1.8	-2.9	-0.1	-1.6	-0.5	-3.3	-1.3	-3.9	-1.3	0.1	-0.4
Pain type(s) experienced in last month: Hip pain	2.5	3.2	10.9	-3.3	0.6	-1.6	-2.5	-2.4	0.1	0.8	-1.4	-1.9	-1.3	1.4	-1.3	-1.2	-2.8	0.4	-3.0	-0.6	0.4	2.6
Age started oral contraceptive pill	2.5	3.2	9.2	-0.2	-2.9	-1.1	-0.3	3.0	2.4	-3.0	-1.7	-0.0	-0.4	-3.0	-1.0	-0.6	-0.1	-2.3	-2.0	-0.5	-0.1	-2.4
Financial difficulties in last 2 years	2.4	3.2	14.7	-2.6	1.4	-2.4	-2.5	-3.8	-1.0	1.9	-1.2	-1.4	-1.7	1.7	-1.8	0.8	-2.3	0.5	-1.1	-1.0	-0.1	1.7
Back pain experienced in last month	2.4	3.5	12.7	-3.0	2.3	-0.5	-0.3	-3.6	-0.9	2.5	-0.6	-1.3	-1.4	2.9	0.0	0.2	-2.5	1.1	-2.5	0.3	-0.2	3.1
Diabetes (father)	2.2	2.7	5.9	-0.7	2.1	0.7	0.8	-1.8	-1.8	2.3	2.1	2.0	0.2	2.4	2.0	-1.7	0.3	1.9	1.8	1.9	1.9	0.8
Alcohol intake versus 10 years previously	2.2	3.3	8.6	0.9	2.8	1.8	0.7	-2.9	-2.4	2.9	-0.4	-0.0	1.6	2.7	1.1	-0.6	0.3	2.2	1.6	1.1	1.4	2.9
Chest pain or discomfort	2.2	3.2	12.5	-3.5	1.3	-1.2	-3.5	-2.7	0.2	1.6	-1.1	-1.9	-1.4	2.0	0.2	-0.2	-2.4	0.7	-2.6	0.5	0.8	1.4
Qualifications: A levels/AS levels or equivalent	2.1	4.7	25.9	5.1	-1.9	0.1	2.2	3.2	1.2	-2.3	1.7	1.0	2.1	-2.4	0.2	-1.7	1.9	-1.0	3.5	-1.3	-1.5	-2.2
Ever taken oral contraceptive pill	2.1	2.3	10.8	-1.8	2.0	0.1	-0.7	-3.3	-2.9	3.0	0.5	-0.0	-0.0	2.3	0.4	0.2	-1.0	1.3	0.8	1.0	0.2	0.9
Heart disease (siblings)	2.1	2.6	10.7	-3.3	0.4	-1.6	-0.9	-1.3	0.3	0.6	-3.1	-3.2	-0.7	0.9	-0.4	0.6	-1.8	0.4	-3.1	0.5	1.2	-0.2
Qualifications: CSEs or equivalent	2.0	2.7	7.5	-1.0	2.5	0.6	-1.9	-2.7	-2.1	2.5	1.2	0.3	0.3	2.5	1.2	0.7	-0.1	2.4	-0.1	1.6	1.4	1.8
Noisy workplace	2.0	2.5	8.7	-1.7	2.5	1.2	-1.4	-2.1	-0.7	2.2	1.2	-0.1	-0.6	2.9	2.0	0.4	-0.9	1.8	-0.3	1.5	-0.3	2.4
Asthma (self-reported)	2.0	4.1	21.6	-3.5	-0.8	-2.1	-4.7	-0.4	1.3	-0.4	-1.0	-3.6	-2.4	-0.2	-0.5	0.1	-2.9	-1.7	-2.2	-1.4	-1.2	0.8
Ulcerative Colitis (UC)	1.9	3.5	9.9	0.8	2.5	3.1	1.9	-0.4	-1.8	2.1	1.0	1.3	1.2	2.4	2.6	0.5	2.2	2.6	-0.1	2.6	2.6	0.2
Ulcerative Colitis	1.9	2.8	10.5	1.5	1.8	3.2	0.4	0.5	-1.6	1.3	0.8	1.4	1.8	1.3	1.9	1.4	2.9	2.2	0.2	2.3	1.7	0.4
Hearing difficulty/problems: Yes	1.9	2.9	15.7	-4.0	0.7	-1.2	-2.8	-2.1	0.1	1.2	-0.5	-2.2	-1.6	1.3	-0.1	-0.3	-2.9	-0.8	-1.6	-0.1	-2.3	0.9
Falls in the last year	1.9	2.6	9.7	-1.7	-1.6	-3.1	-2.1	-0.0	0.9	-0.9	-1.8	-0.9	-1.8	-1.0	-2.2	-0.7	-2.9	-1.5	-1.7	-1.8	-1.1	0.2
Chronic bronchitis/emphysema (mother)	1.9	2.3	6.9	-1.9	2.1	0.3	-1.1	-2.5	-1.8	2.6	-0.8	-0.7	-0.3	2.5	0.7	-1.6	-1.2	1.7	-1.3	0.8	1.3	1.1
Medication: Omeprazole	1.9	2.3	8.6	-2.0	-0.5	-1.6	-1.5	-0.3	1.7	-0.9	0.4	0.6	-2.5	-0.6	-2.2	0.1	-2.3	-1.2	-0.3	-2.9	-2.1	-1.0
Family relationship satisfaction	1.9	2.3	7.1	1.4	-2.1	-2.2	0.6	1.5	1.5	-1.7	-1.7	-1.3	2.1	-1.8	-0.7	0.5	-1.3	-1.5	-1.4	-1.2	-2.7	-0.4
Pain experienced in last month	1.9	3.2	18.8	4.3	-0.9	1.3	1.4	2.6	-0.7	-0.9	0.1	0.6	2.7	-1.4	0.9	-0.2	3.0	-0.1	3.3	1.2	0.8	-1.1
Hearing difficulty/problems with background noise	1.8	2.8	16.4	-3.5	0.4	-2.4	-1.2	-2.0	0.5	1.1	-0.6	-2.7	-1.9	1.4	-0.1	0.7	-4.0	-0.6	-0.6	-0.5	-0.5	0.6
Asthma	1.8	3.6	19.4	-3.3	-0.7	-1.9	-4.4	-0.3	1.3	-0.4	-0.8	-3.6	-2.1	-0.0	-0.3	0.4	-2.6	-1.4	-1.9	-1.3	-0.9	1.2
Age at first live birth	1.8	3.1	13.5	3.7	-1.5	1.0	2.1	2.5	0.4	-1.7	0.0	0.9	1.2	-2.2	0.2	-0.1	2.7	-1.4	2.1	-0.6	-2.4	-2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	9.5	-3.1	-0.7	-2.1	-0.1	-0.6	1.6	-0.8	-1.3	-1.9	-0.5	0.1	-0.6	-0.3	-2.7	-0.7	-2.3	-1.0	-1.2	1.3
Angina	1.7	2.2	7.4	-2.7	1.5	0.9	-2.5	-1.2	-0.1	1.2	-0.9	-2.1	-1.4	1.8	1.3	1.2	-0.4	0.5	-2.6	0.5	0.4	1.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.4	15.2	1.6	2.0	2.5	3.1	-0.4	-2.7	1.9	3.9	3.0	2.4	2.0	2.3	0.2	2.8	3.0	1.4	3.2	2.3	1.3
Wheeze or whistling in the chest in last year	1.7	3.1	16.1	-3.4	0.2	-1.4	-4.0	-1.7	0.0	0.8	-0.8	-2.5	-2.4	0.9	-0.3	-2.4	-2.4	-0.4	-1.7	-0.6	0.5	0.4
Medication for pain relief, constipation, heartburn	1.7	2.9	11.2	3.3	-0.5	1.8	2.0	1.8	-0.6	-0.5	1.6	1.9	2.9	-0.4	1.6	-1.4	2.7	0.3	2.0	1.7	0.7	-0.1
Schizophrenia (2018)	1.6	3.3	11.3	-2.3	-1.8	-2.3	-0.2	0.8	3.4	-2.3	-2.2	0.1	-2.7	-1.8	-1.7	0.1	-2.3	-2.0	-1.5	-1.5	-1.7	-0.5
Major Depression (MDD)	1.6	1.9	8.0	-1.9	0.5	-1.8	-0.0	-2.2	-0.4	1.3	-1.7	-2.1	-0.6	0.9	-0.9	-0.5	-2.8	0.6	-2.0	-0.2	1.2	1.1
Average weekly spirits intake	1.6	2.0	8.2	1.9	1.8	1.1	-0.6	-1.5	-2.1	2.2	1.6	1.0	-1.2	1.3	0.0	-0.0	1.1	1.3	2.9	0.8	0.7	1.2
Sensitivity / hurt feelings	1.6	2.8	9.4	-3.1	0.1	-1.5	-2.6	-1.6	0.3	0.4	-2.9	-2.6	-1.7	0.5	-0.4	-0.7	-2.3	-1.2	-2.5	-0.8	-0.0	-1.6
Supplements: Glucosamine	1.6	2.1	7.5	-2.3	-0.7	-0.9	-0.1	-0.9	1.4	-0.5	-2.1	-1.7	-2.7	-0.5	-1.1	-1.8	-2.2	-1.8	-1.3	-0.9	-0.2	-1.4
Angina (self-reported)	1.6	2.1	6.8	-2.5	1.6	0.9	-2.6	-1.3	-0.1	1.2	-0.7	-2.2	-1.4	1.9	1.5	0.8	-0.4	0.5	-2.4	0.5	0.4	1.4
Overall health rating	1.6	3.3	12.7	-3.6	1.1	-2.4	-1.4	-2.8	-0.8	1.9	-0.6	-1.8	-1.8	1.8	-1.1	0.1	-3.4	0.4	-2.6	-0.7	1.0	1.3
Miserableness	1.6	2.8	11.5	-3.4	-0.2	-1.9	-2.0	-1.8	0.9	0.4	-2.0	-2.2	-2.2	0.2	-1.5	0.0	-3.4	-0.8	-2.2	-0.9	0.1	0.0
Number of treatments/medications taken	1.5	2.6	9.9	-3.1	-0.8	-1.3	-1.8	-0.1	1.3	-0.6	-2.0	-2.2	-2.4	-0.6	-1.6	1.3	-2.1	-0.6	-3.1	-1.2	-0.0	-0.3
Townsend deprivation index at recruitment	1.5	2.1	5.9	-0.5	2.2	1.6	0.4	-1.4	-0.6	1.3	1.7	1.0	0.7	2.4	2.3	1.6	1.5	1.9	-0.8	1.0	0.3	2.2
Neuroticism score	1.5	3.1	12.1	-3.5	0.5	-2.1	-3.0	-2.5	0.1	0.7	-1.6	-1.9	-1.8	1.0	-1.1	-1.4	-2.7	-0.3	-2.6	-0.3	-0.3	-1.5
Number of full sisters	1.5	1.9	11.7	-3.4	1.0	-1.1	-0.8	-2.2	-0.7	1.5	0.6	-0.0	-0.0	1.6	0.4	0.1	-2.3	0.6	-1.6	0.7	0.3	1.9
Handedness (chirality/laterality): Left-handed	1.5	1.8	5.3	-2.0	1.6	0.9	-0.5	-1.6	-2.0	2.3	-0.3	-1.1	-1.7	1.4	0.5	1.8	-0.6	1.2	-0.2	1.0	1.8	0.2
Commuting to job workplace: Walk	1.5	1.6	5.8	1.0	0.7	1.8	1.1	0.4	-0.3	0.1	1.1	2.0	1.3	0.8	2.4	-0.7	2.1	1.1	-0.5	2.3	0.3	0.1
Medication: Gliclazide	1.5	1.7	5.4	-1.0	1.5	-0.6	1.2	-2.1	-1.6	2.3	1.2	0.3	-1.4	1.9	-0.7	0.2	-1.6	0.8	-0.8	0.8	-0.1	2.3
Number of self-reported non-cancer illnesses	1.5	2.6	9.4	-2.1	-1.1	-1.5	-2.3	-0.1	1.9	-1.1	-1.3	-2.2	-2.1	-0.4	-1.2	-0.0	-2.6	-0.6	-3.1	-1.1	-1.5	1.5
Average weekly champagne plus white wine intake	1.5	2.1	12.1	0.5	-2.0	-1.6	-1.3	1.0	-0.3	-0.5	-0.7	-1.0	-1.6	-2.1	-3.5	1.5	-2.0	-1.4	0.3	-1.6	-0.5	0.1
Breast Cancer	1.4	3.4	10.3	2.2	1.9	1.8	0.3	-1.0	-3.2	2.7	2.1	2.3	0.5	1.4	1.8	-1.8	1.9	1.5	2.4	2.2	1.6	0.0
Fasting Glucose	1.4	1.6	5.0	0.4	-1.8	-0.9	0.1	1.7	0.8	-1.8	-0.7	-0.6	-1.2	-2.0	-2.0	-1.5	-0.2	-2.2	-0.2	-1.7	-0.5	-1.2
Waist Hip Ratio (WHR)	1.4	6.5	15.4	0.7	3.2	3.5	-0.1	-1.5	-2.6	3.3	3.0	1.4	1.5	3.3	3.1	-2.5	1.6	3.6	1.2	3.9	1.4	3.6
Chronotype (morning person)	1.4	3.1	13.2	-0.9	3.3	1.0	1.7	-2.5	-0.2	2.1	1.3	-0.7	1.2	3.6	2.8	0.4	0.7	2.3	1.3	1.8	0.7	1.1
High blood pressure (mother)	1.4	1.9	6.2	0.8	1.5	1.9	0.8	-0.8	-1.8	1.7	1.2	1.9	0.0	1.3	1.1	-1.0	1.6	1.8	0.7	2.5	1.7	0.2
Commuting to job workplace: Car/motor vehicle	1.4	1.6	5.2	-2.3	0.1	-1.5	-1.5	-0.9	-0.1	0.6	-1.2	-2.0	-1.4	0.5	-1.0	-1.6	-2.1	-0.0	-1.9	-0.1	0.9	0.9
Bipolar Disorder or Schizophrenia	1.3	3.3	8.6	-2.4	-1.8	-2.4	-0.1	-0.4	2.5	-1.6	-1.8	0.9	-2.8	-1.6	-2.3	-0.3	-2.4	-2.9	-1.5	-1.6	-1.7	-0.8
Depressed Affect (Nagel 2018)	1.3	2.7	10.2	-3.2	0.3	-1.6	-2.5	-2.1	0.0	1.0	-2.9	-2.1	-0.9	0.7	-1.0	-0.8	-2.8	-0.5	-1.2	-0.2	0.8	-1.5
Prostate Cancer	1.3	1.9	4.7	-0.2	1.7	0.9	-0.8	-1.5	-2.2	2.2	0.8	-0.9	-0.4	1.9	1.5	-0.0	1.0	2.1	0.5	2.0	2.0	0.8
Impedance of leg (left)	1.3	6.4	15.4	0.8	3.8	3.3	-1.2	-3.8	-3.0	3.9	2.3	2.3	1.4	3.5	2.2	-0.1	1.1	3.0	3.5	1.3	2.3	1.8
Alcohol usually taken with meals	1.3	2.0	13.3	0.9	-1.3	-1.3	2.2	1.2	1.2	-1.4	-1.9	-0.2	0.0	-1.2	-0.4	-1.6	-0.2	-1.8	0.4	-1.6	-0.3	-3.6
Forced vital capacity (FVC)	1.3	5.1	14.4	0.7	2.2	2.9	1.5	-1.0	-3.3	2.6	3.8	2.2	1.1	2.2	2.9	-0.2	2.4	3.1	0.9	3.8	1.6	1.1
Pain all over the body in last month	1.3	1.3	4.9	-1.6	0.9	-0.8	-0.1	-2.0	-0.7	1.6	0.6	-0.9	-1.0	1.7	0.5	-0.6	-2.2	0.6	-1.2	0.6	0.4	1.7
Forced expiratory volume in 1-second (FEV1)	1.3	4.4	13.5	0.7	1.9	2.1	1.9	-0.8	-2.7	2.1	3.7	2.7	1.1	1.9	2.5	-0.2	2.1	2.8	0.8	3.6	1.8	1.1
Medication: Paracetamol	1.3	2.2	9.4	-1.9	2.3	-0.4	-2.0	-3.1	-1.4	2.3	-0.6	-0.7	-1.0	2.5	0.3	0.9	-1.0	0.9	-0.6	0.4	1.7	-0.1
Irritability	1.3	2.2	18.1	-1.6	1.1	-0.4	-4.2	-2.0	-1.2	1.8	-0.5	0.0	-1.0	1.4	0.5	0.2	-1.9	0.5	-0.4	0.9	-0.5	-2.2
Neuroticism (Nagel 2018)	1.2	2.7	13.8	-3.7	0.6	-1.1	-2.7	-2.0	0.3	0.8	-2.7	-1.9	-1.1	1.2	0.0	-0.1	-2.5	-0.2	-2.4	0.2	0.2	-1.2
Neuroticism	1.2	2.8	14.6	-3.8	0.9	-1.3	-2.3	-2.4	0.1	0.8	-2.2	-1.9	-1.3	1.3	-0.1	-1.3	-2.5	0.2	-2.4	0.3	0.6	-1.3
Hair/balding pattern: Pattern 2	1.2	1.6	3.7	-1.4	-1.4	-1.0	-0.0	1.0	1.2	-1.0	-1.1	-1.6	-1.3	-1.5	-0.6	1.5	-1.9	-1.5	-1.0	-1.1	-1.6	-1.5
Loud music exposure frequency	1.2	1.3	4.8	0.5	1.4	1.0	1.4	-0.2	-0.2	0.6	2.1	0.6	0.6	1.1	0.5	0.6	1.3	2.2	-0.5	1.4	-0.5	2.0
Forced vital capacity (FVC), Best measure	1.2	4.3	12.7	1.4	2.0	2.9	2.3	-0.4	-2.6	1.8	3.6	2.2	1.5	1.9	2.5	-0.2	2.6	2.7	1.4	2.6	1.6	1.1
Health satisfaction	1.2	1.6	6.6	-1.5	0.0	-2.3	-0.6	-1.5	-1.0	1.1	-0.3	-1.1	-1.0	0.7	-1.6	0.2	-2.6	-0.2	-2.2	-0.7	1.0	0.2
Medication: Ibuprofen	1.2	1.5	4.8	-1.4	0.1	-1.2	-0.8	-2.0	-1.4	1.2	0.8	-0.8	-2.0	0.2	-1.9	0.4	-2.2	-0.6	-0.6	-1.5	-0.4	1.0
Ever had bowel cancer screening	1.2	1.4	3.2	-1.6	-1.4	-0.8	-1.5	0.6	0.5	-0.9	-1.0	-1.5	-1.4	-1.1	-1.0	1.2	-1.8	-1.4	-0.8	-1.3	0.3	-1.8
Friendships satisfaction	1.2	1.5	6.5	-1.5	-0.3	-1.5	-2.3	-1.0	1.1	0.2	-0.8	-2.0	-0.1	0.3	-0.0	1.5	-2.5	-0.5	-1.1	-0.7	-1.5	0.8
Financial situation satisfaction	1.2	1.5	11.4	-0.8	1.1	-2.2	-0.4	-3.4	-0.6	1.6	1.1	0.2	-0.4	1.6	-0.1	0.6	-1.6	-0.0	0.4	-0.4	-0.8	1.2
Alcohol drinker status: Previous	1.2	1.3	4.7	-0.6	1.7	0.4	-0.7	-1.3	-0.9	1.4	0.4	0.6	-0.5	2.2	1.4	2.0	0.5	1.6	-1.2	1.3	0.6	0.7
Intelligence (Savage-Jansen 2018)	1.1	3.3	14.1	2.5	-2.8	-0.6	1.9	3.8	2.4	-3.5	1.0	1.2	1.2	-2.8	-0.5	-1.0	1.2	-0.5	-0.6	0.3	-1.0	-0.5
Schizophrenia (2014)	1.1	2.4	9.5	-2.3	-1.3	-1.4	0.4	0.5	2.9	-1.8	-1.2	0.5	-3.1	-1.5	-1.4	0.1	-1.7	-1.9	-1.4	-1.3	-0.9	-0.7
Impedance of leg (right)	1.1	5.1	12.0	0.7	3.4	3.0	-1.5	-3.4	-2.7	3.5	2.4	2.1	1.2	3.0	2.0	0.1	1.0	2.5	3.1	0.8	1.5	2.0
Qualifications: None of the above	1.1	2.4	14.7	-3.8	1.8	-0.2	-0.9	-2.2	-0.6	1.5	-2.4	-1.2	-1.3	2.3	0.8	0.8	-1.0	0.1	-1.7	0.8	1.2	1.1
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	5.4	-1.3	0.2	-1.0	-0.6	-1.8	-1.4	1.3	1.0	-0.4	-2.3	-0.0	-1.6	0.2	-2.0	-0.2	-0.0	-1.5	-1.0	0.8
Depression (self-reported)	1.1	1.3	5.1	-1.4	-0.4	-1.5	-1.4	-0.7	0.2	-0.0	-0.5	0.6	-1.8	-0.0	-1.7	0.0	-2.0	-0.6	-2.2	-1.1	-1.2	-0.2
Exposure to tobacco smoke at home	1.1	1.3	3.4	-0.4	1.5	1.3	-0.3	-1.3	-1.4	1.1	1.0	1.1	0.2	1.2	0.6	-1.0	1.6	1.2	1.2	0.1	1.5	1.8
Shortness of breath walking on level ground	1.1	1.3	6.1	-1.9	1.1	-0.8	-0.1	-2.5	-1.0	1.7	-0.6	-0.1	-0.4	1.6	-0.5	-0.1	-1.8	0.6	-0.6	0.1	1.6	0.3
Eye problems/disorders: None of the above	1.1	1.3	7.5	2.7	1.1	0.8	1.1	-0.3	-1.1	1.1	2.0	1.7	1.0	0.8	0.3	-0.2	0.6	1.2	1.3	-0.0	-0.0	0.7
Mouth/teeth dental problems: Loose teeth	1.1	1.3	7.7	-0.5	1.3	0.6	-0.6	-1.6	-1.4	1.4	0.9	1.5	-0.6	1.4	-0.2	0.8	0.1	1.3	-0.6	1.1	2.8	0.4
Medication: Aspirin	1.1	1.4	4.5	-1.8	-0.3	-0.9	-1.5	-0.3	0.3	0.1	-1.7	-2.1	-1.6	-0.1	-0.7	2.0	-1.6	-0.2	-1.9	-0.8	-0.5	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.2	5.6	-1.6	0.8	-0.9	-0.3	-2.4	0.3	0.4	0.8	0.8	-1.8	0.7	-1.0	-1.9	-1.0	-0.1	-0.8	-1.6	-0.8	0.6
Number of operations (self-reported)	1.1	1.7	8.1	0.2	-1.4	-1.4	-2.8	-0.1	-0.2	-0.5	-1.2	-1.0	-0.7	-1.6	-2.5	-0.5	-1.0	-1.9	0.5	-2.0	-1.0	-0.2
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	4.6	-1.2	-0.1	-1.4	-1.8	-0.9	0.3	0.1	0.5	0.6	-1.9	-0.2	-2.0	0.5	-2.1	-0.9	0.4	-2.1	-1.1	-0.6
Supplements: Calcium	1.1	1.2	3.4	0.3	-1.8	-1.2	0.1	1.1	1.0	-1.7	-1.3	-0.7	0.1	-1.8	-1.3	-0.8	-0.4	-1.5	-1.6	-1.0	-0.6	0.7
Verbal and Numeric Reasoning (VNR)	1.0	2.4	8.7	2.7	-2.1	0.1	0.8	3.0	1.0	-2.3	1.2	2.2	1.3	-2.4	-0.9	-1.1	1.6	-0.2	-0.1	0.4	-1.3	0.0
Age at First Birth	1.0	1.5	8.3	2.2	-0.1	1.6	1.4	1.0	0.2	-0.9	1.9	1.3	1.3	-0.6	0.9	0.7	2.9	-0.1	1.0	-0.5	-0.7	-0.2
Coronary Artery Disease (CAD)	1.0	1.2	5.3	-0.3	1.1	1.9	-1.4	0.3	0.0	0.4	1.7	2.3	0.4	1.0	1.6	0.6	0.9	1.5	0.3	0.8	0.8	0.6
Fed-up feelings	1.0	1.8	8.0	-2.8	1.1	-0.5	-2.0	-2.2	-1.0	1.6	-1.3	-1.0	-0.2	1.5	-0.1	-0.9	-1.7	0.9	-1.8	0.6	0.3	-0.3
Age when periods started (menarche)	1.0	2.3	7.5	2.3	1.0	2.1	2.1	0.1	-1.9	1.1	2.7	1.6	1.0	0.2	0.8	0.2	2.1	1.7	1.7	1.1	-0.6	1.7
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.6	5.1	-2.3	-0.4	-1.6	-1.4	-1.1	0.9	-0.6	-1.7	-1.0	-1.5	-0.3	-1.2	0.2	-1.4	-0.5	-1.9	-1.8	-1.2	-1.2
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	4.9	-0.8	1.0	1.4	2.1	-0.7	0.7	0.2	1.2	-0.0	1.2	1.2	1.8	0.2	0.7	1.6	-0.5	1.6	-0.8	2.2
Lung cancer (father)	1.0	1.1	5.4	-2.3	0.7	0.4	-1.8	-1.4	-0.3	0.7	-0.8	-1.6	-1.0	1.1	0.8	-0.7	-1.5	1.0	-0.4	0.4	-0.2	1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	10.9	-3.3	0.5	-1.4	-1.1	-0.6	1.4	-0.3	-1.4	-1.4	0.3	0.3	-0.7	-0.4	-1.7	0.1	-2.2	-1.0	-0.4	0.2
Peak expiratory flow (PEF)	1.0	2.3	6.1	0.3	1.7	0.7	1.8	-1.6	-1.9	1.9	2.5	1.5	1.5	1.6	1.2	-0.9	1.0	2.2	-0.7	2.4	1.4	0.8
Exposure to tobacco smoke outside home	1.0	1.4	3.2	-0.2	1.7	1.2	1.5	-0.8	-0.7	1.3	0.0	-0.2	1.7	1.7	1.8	-1.5	1.0	1.4	0.1	1.4	-0.0	1.3
Emphysema/chronic bronchitis	1.0	1.2	3.6	-1.3	0.8	-0.6	-1.5	-0.9	0.6	0.3	0.2	-1.3	0.5	1.0	0.1	-1.9	-1.3	0.3	-0.5	-1.7	-1.9	1.3
Neck or shoulder pain in last month	1.0	1.4	7.8	-2.2	-0.5	-1.0	-0.8	-0.1	1.5	-1.1	-0.5	-0.8	-1.1	-0.7	-1.6	-0.2	-0.5	-0.4	-2.8	-1.8	-0.7	0.5
Illness, injury, bereavement, stress in last 2 years	1.0	1.3	4.4	2.1	-1.4	0.0	2.0	1.9	0.9	-1.5	-0.6	1.3	0.1	-1.2	0.0	-0.2	0.8	-1.4	1.1	0.2	0.6	-0.6
Supplements: Vitamin C	1.0	1.1	6.1	-0.8	1.9	0.9	0.3	-2.5	-1.6	1.7	0.5	0.3	0.3	1.5	0.4	-0.2	0.8	0.6	1.4	0.0	0.4	0.3
Tinnitus: Yes, now most or all of the time	1.0	1.2	7.4	-0.2	-1.1	-1.0	-1.8	0.8	0.7	-1.3	-2.0	-2.7	-0.5	-1.1	-0.3	0.2	-0.2	-1.0	-0.9	-0.8	0.2	-0.1
Medication: Paracetamol	1.0	1.5	4.5	-2.1	1.1	-0.9	-1.7	-1.8	-0.4	1.0	-0.6	-1.5	-1.1	1.6	-0.2	1.3	-1.3	0.1	-1.5	0.2	2.0	-0.4
Alzheimer’s Disease (in mother)	0.9	1.1	4.8	-2.2	-0.0	-0.9	-0.5	-0.8	-0.8	1.0	-1.5	-1.4	-1.2	0.2	-0.9	0.6	-2.0	-0.2	-1.0	0.1	1.4	-0.0
Systolic Blood Pressure	0.9	4.3	10.0	0.2	2.9	2.9	-0.1	-2.1	-2.9	3.0	1.6	0.5	-1.0	3.1	2.6	-0.1	1.8	3.2	0.9	3.0	1.9	0.8
Ever used hormone-replacement therapy (HRT)	0.9	1.1	3.1	-1.2	-1.0	0.1	-1.8	0.8	1.6	-1.1	-0.8	-1.2	-1.6	-1.2	-1.1	-0.1	-1.1	-0.9	-0.6	-1.7	0.3	-0.5
Current tobacco smoking	0.9	1.5	9.2	-3.0	0.2	-0.8	-0.5	-0.7	0.3	0.5	-1.4	-1.6	-0.8	0.8	0.1	-0.9	-2.0	0.4	-2.6	0.7	0.8	0.2
Medication: Levothyroxine sodium	0.9	1.5	5.1	-2.0	-0.9	-1.8	-0.3	0.4	2.3	-1.4	-1.6	-0.1	-0.8	-0.5	-0.8	0.3	-1.6	-1.4	-2.1	-1.1	-0.4	0.3
Prospective memory result	0.9	1.1	4.4	-1.8	0.5	-1.0	-0.6	-1.8	0.1	0.7	-0.1	-0.3	-0.5	0.7	-0.9	0.9	-2.1	-0.5	-0.8	-1.0	-1.6	1.2
Breastfed as a baby	0.9	1.1	4.9	0.2	-1.4	0.1	-0.6	2.2	1.1	-1.4	-0.7	0.2	-0.5	-2.2	-1.6	0.4	0.2	-1.2	0.1	-1.3	-0.8	-0.8
Hair/balding pattern: Pattern 4	0.9	2.1	6.6	1.4	2.3	1.7	1.1	-0.9	-0.9	1.5	0.5	0.2	1.7	2.0	1.9	-0.4	1.8	2.6	0.9	1.4	0.4	2.1
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	8.3	2.5	-0.5	0.4	0.6	1.3	0.4	-0.8	2.9	2.0	1.5	-1.0	-0.1	-1.2	1.7	-0.1	0.4	0.4	-0.2	-0.3
Worry too long after embarrassment	0.9	1.5	5.1	-1.9	-0.8	-1.5	-1.9	-0.4	1.3	-0.9	-1.1	-1.5	-1.7	-0.6	-0.7	-0.3	-0.6	-1.4	-0.5	-1.6	-0.8	-2.2
Medication: Blood pressure	0.9	1.6	5.1	-1.1	1.8	1.2	0.0	-0.9	-1.7	2.1	0.4	0.2	0.4	2.0	1.3	0.6	0.3	2.2	-0.7	2.3	0.8	0.1
Heart disease (mother)	0.9	1.1	6.9	-0.3	-0.8	-0.5	-1.6	0.7	1.1	-0.8	-1.9	-2.6	-0.9	-1.0	-0.4	-0.6	-0.6	0.0	-1.4	-0.9	-0.6	0.1
Osteoarthritis (self-reported)	0.9	1.2	6.3	-1.6	-0.3	-0.5	-2.5	-0.5	0.7	-0.2	-0.7	-1.3	-1.3	-0.4	-0.8	-0.8	-1.9	-0.2	-0.5	-1.3	-1.5	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	4.8	0.2	1.0	2.2	2.0	0.8	-0.9	0.5	2.2	1.9	1.6	0.7	1.3	-0.4	2.1	1.7	1.4	1.1	1.7	-0.3
Medication: Atorvastatin	0.9	1.2	9.0	-0.3	-0.4	-0.1	-2.1	-0.2	-0.3	0.6	0.8	0.3	-3.0	-0.7	-1.4	-0.4	-0.9	-0.5	-1.1	-1.2	0.2	1.4
Ever depressed for a whole week	0.9	1.1	5.4	-1.0	0.2	-0.7	-2.3	-1.0	-0.3	0.8	-0.5	-1.8	-2.0	0.4	-0.8	-0.6	-1.8	-0.6	-0.5	-0.7	0.7	0.7
Schizophrenia vs Biploar Disorder	0.8	1.1	4.9	-0.7	-0.4	-1.3	0.5	0.4	2.2	-1.3	-1.5	-0.1	-0.6	-0.8	-0.5	0.0	-0.7	-0.8	-0.6	-1.5	1.6	-1.4
Mean Putamen Volume	0.8	0.9	3.8	-0.3	1.4	0.2	0.8	-1.6	0.1	0.9	1.4	1.9	0.4	1.5	1.0	-0.6	0.0	0.2	-0.2	-0.2	1.3	0.3
LDL Cholesterol	0.8	1.3	5.9	0.0	-1.1	-1.5	-1.2	0.1	0.6	-0.7	-2.2	-1.1	-1.0	-1.2	-1.4	0.4	-0.5	-2.4	0.1	-1.8	0.3	-0.8
Neuroticism (2016)	0.8	1.2	6.6	-1.6	0.2	-1.3	-2.6	-1.2	0.6	0.3	-1.1	0.0	-1.0	0.4	-0.5	-0.4	-1.2	-0.5	-1.1	-0.0	-0.2	-2.3
Lung FVC	0.8	4.0	10.6	-0.2	2.5	3.1	1.5	-0.3	-1.4	1.7	3.2	2.1	1.5	2.2	2.9	1.2	2.5	2.9	0.6	2.3	1.6	1.3
Frequency of depressed mood in last 2 weeks	0.8	1.2	3.6	-1.9	-0.0	-1.1	-1.8	-1.1	0.4	0.3	-1.0	-1.2	-0.9	0.2	-0.8	-0.4	-1.7	-0.5	-1.7	-1.7	-0.9	-0.2
Severe depression (siblings)	0.8	0.9	3.4	-1.3	-1.3	-0.6	-0.9	0.9	0.7	-0.7	-0.2	1.0	-0.1	-1.1	-1.1	-0.4	-1.4	0.1	-1.8	-0.4	-1.1	0.2
Serious illness, injury or assault to yourself	0.8	1.0	3.0	-1.0	-1.5	-1.2	-1.7	0.7	1.0	-0.9	-0.5	-0.2	0.4	-1.1	-0.9	-0.5	-1.6	-0.6	-1.5	-0.7	-1.2	-0.5
Had menopause	0.8	1.1	3.8	-0.8	-1.1	-0.6	-0.5	0.4	0.8	-0.7	-1.9	-1.3	-1.5	-1.0	-0.5	-0.9	-0.8	-1.9	-1.0	-1.0	0.5	-1.1
Allergy	0.8	1.8	10.2	1.9	-1.1	-0.5	2.6	1.6	-0.0	-1.0	0.1	2.3	1.1	-1.2	-0.7	0.3	0.8	-0.6	0.7	0.1	1.2	-3.2
Medication: Ramipril	0.8	1.1	2.9	-0.1	1.4	1.0	1.5	-0.3	-1.2	1.2	1.0	0.5	-0.2	1.3	1.6	-0.6	1.3	1.5	-0.7	1.7	0.6	-0.4
Fluid intelligence score	0.8	1.7	5.9	1.8	-2.1	-0.5	0.3	2.3	1.2	-2.2	0.5	1.2	-0.0	-2.4	-1.5	-0.9	0.7	-1.0	0.9	-0.8	-0.9	-0.5
Worrier / anxious feelings	0.8	1.5	9.0	-3.0	0.2	-0.4	-1.8	-0.5	0.8	-0.1	-1.1	-0.7	-0.8	0.7	1.3	-0.6	-1.2	0.0	-2.6	0.8	0.5	-1.7
Number of live births	0.8	1.1	7.5	-2.7	1.1	0.5	-0.6	-1.7	-0.9	1.4	0.1	1.1	-1.3	1.2	-0.2	0.5	-0.9	-0.2	0.1	0.3	1.2	0.1
Pulse wave Arterial Stiffness index	0.8	0.9	5.0	-1.9	-0.4	-0.4	2.2	-0.5	0.8	-0.6	-0.4	-0.7	0.1	-0.1	-0.9	-0.6	-1.4	-0.0	-1.2	-0.1	1.6	-0.0
Length of working week for main job	0.8	0.8	4.3	-0.7	-0.0	-1.5	-1.3	-0.7	0.4	0.3	-0.6	-0.7	-1.5	0.2	-0.8	-0.6	-2.1	0.4	-1.2	-0.2	-1.0	-0.7
Gout (self-reported)	0.8	1.1	4.3	1.5	-0.4	0.9	0.1	1.3	1.4	-1.2	-0.0	-0.9	1.0	-0.6	0.0	-1.4	0.4	-0.6	1.6	-1.1	-2.1	-0.6
Number of children fathered	0.8	0.9	2.5	-1.6	1.2	1.2	1.6	-1.0	0.3	0.8	-0.3	-0.1	0.1	1.2	1.5	1.3	-0.3	1.1	0.3	0.8	1.0	0.3
Pulse wave peak to peak time	0.8	1.0	4.5	2.0	0.5	0.4	-2.1	0.3	-1.0	0.8	0.4	0.7	-0.3	0.2	0.9	0.4	1.5	0.0	1.4	0.0	-1.6	-0.1
Medication: Allopurinol	0.8	1.0	2.5	1.2	-0.9	0.2	0.1	1.6	1.5	-1.5	-0.2	-1.5	1.4	-0.9	0.0	-1.0	0.3	-0.5	1.0	-0.8	-1.4	-0.8
Mean time to correctly identify matches	0.8	1.5	7.3	-2.0	-0.9	-1.4	-0.2	-0.1	1.4	-0.5	-1.5	-0.3	-0.5	-0.6	-1.8	0.2	-2.7	-1.6	-0.7	-1.4	-0.2	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	2.5	-1.5	0.2	0.2	-0.3	-0.3	-1.5	1.2	0.7	1.1	-1.5	0.2	-0.8	-0.3	-1.0	1.1	-0.2	1.4	1.3	-1.6
Alcohol intake frequency.	0.8	1.9	9.9	-1.6	1.2	1.2	0.1	-0.6	1.1	-0.3	-0.5	-0.3	1.5	1.7	2.3	0.5	0.9	1.3	-3.1	1.5	1.4	1.8
Mood swings	0.8	1.5	5.1	-2.3	0.4	-1.0	-2.0	-1.5	0.0	0.7	-2.0	-1.9	-0.4	0.8	-0.3	-0.7	-2.1	0.1	-1.0	0.6	-0.3	-1.3
Long-standing illness, disability or infirmity	0.8	1.2	6.9	-1.0	-0.4	-1.3	-2.6	0.2	0.0	0.1	0.0	-1.8	-0.2	-0.3	-0.8	1.0	-1.1	0.3	-1.7	-0.9	-0.9	1.6
Eye problems/disorders: Glaucoma	0.8	1.0	5.9	-1.8	-0.6	-0.3	-1.6	0.2	0.4	-0.1	-0.3	-1.4	-2.4	-0.4	-0.5	0.0	-1.7	-1.0	0.1	-0.1	0.3	-0.6
Illnesses of father: High blood pressure	0.8	1.0	4.4	0.2	0.9	1.5	1.3	-0.3	-0.9	0.7	0.8	-0.2	0.6	0.7	1.3	-0.4	1.7	2.1	0.3	2.0	0.7	-0.3
Average weekly beer plus cider intake	0.8	1.2	4.4	-0.6	2.0	0.6	-0.7	-0.9	0.3	0.8	0.6	0.5	1.5	2.1	1.7	-0.5	0.9	2.0	0.3	0.5	0.6	0.9
Cholesterol lowering medication	0.8	1.2	8.8	-3.0	0.1	-0.7	-0.1	-0.4	0.9	-0.0	-0.3	-0.4	-1.7	0.7	0.2	-1.0	-1.4	-0.4	-2.4	0.2	1.1	0.2
Impedance of whole body	0.8	4.3	11.3	1.0	2.8	2.8	-1.4	-2.9	-2.7	3.4	2.2	2.5	0.8	2.4	1.6	-0.1	0.6	1.9	3.2	1.1	1.5	1.6
Depression (Nagel 2018)	0.7	1.1	5.5	-2.3	0.6	-0.9	-0.2	-1.9	-0.3	1.0	-1.3	-0.6	-0.5	1.0	-0.1	0.1	-1.8	0.2	-1.7	-0.0	0.3	-0.5
Worry (Nagel 2018)	0.7	1.4	4.6	-1.9	1.6	0.9	-0.2	-1.9	-0.7	1.0	-0.0	-0.2	-0.0	2.0	1.5	1.3	-0.2	1.4	-2.1	1.3	0.1	0.3
Alzheimer’s Disease (in father)	0.7	0.7	2.3	0.6	-0.5	1.2	-0.3	1.3	0.6	-0.8	1.5	1.3	-0.4	-0.7	0.8	0.2	0.6	0.4	-1.5	0.7	-0.2	0.8
Crohns Disease (2017)	0.7	1.5	7.0	-0.9	-1.0	-1.6	-0.0	-0.3	0.7	-0.2	-1.9	-0.0	-1.2	-0.4	-0.8	-0.2	-2.7	-1.5	-2.2	-0.6	0.3	-2.3
Primary Biliary Cirrhosis	0.7	0.9	4.5	-2.1	0.9	0.7	-0.3	-1.2	-0.8	0.8	0.5	0.8	-0.0	1.1	0.5	1.1	0.4	0.9	-1.1	1.4	0.9	-1.1
BMI	0.7	4.1	10.7	-1.2	-2.4	-3.0	-0.4	1.2	2.6	-2.5	-1.3	-1.9	-2.0	-2.0	-2.5	-0.9	-2.2	-2.4	-2.3	-2.2	-3.3	-0.2
Medication for hormone replacement therapy	0.7	0.8	3.7	0.4	-1.1	-0.9	-1.3	0.4	0.7	-0.7	0.2	-0.8	-1.3	-1.1	-1.1	-0.0	-1.3	-0.8	0.1	-1.9	-0.4	0.3
Medication: Co-codamol	0.7	0.8	4.1	-2.0	0.4	-0.4	-1.1	-0.9	1.2	-0.8	-0.6	0.3	-1.2	0.2	-0.5	0.8	0.2	-0.7	-1.5	-1.1	-0.8	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	3.8	-1.5	1.2	-0.4	-0.4	-2.0	-0.9	1.4	-0.1	-0.4	-0.5	1.5	0.5	-1.2	-1.0	0.8	-1.7	0.4	0.1	0.2
Mouth/teeth dental problems	0.7	1.0	6.0	1.9	-0.9	-0.4	0.8	0.9	1.1	-1.0	0.5	1.1	1.4	-1.1	0.2	0.6	-0.0	-0.4	2.4	-0.1	-0.7	-0.4
Heart attack	0.7	0.9	4.5	-1.3	0.9	-0.0	-0.8	-1.2	-1.3	1.6	-0.9	-1.0	-2.1	1.1	-0.0	0.6	-0.7	0.3	0.7	0.5	-0.3	-0.6
Illnesses of siblings	0.7	1.0	5.3	2.1	0.1	1.0	1.8	0.4	-0.6	0.1	0.4	-0.3	-0.4	-0.3	0.5	-0.9	1.3	-1.1	2.3	-0.3	-0.7	0.0
Hip circumference	0.7	3.2	9.7	-0.1	-3.0	-3.1	-0.6	1.4	1.1	-2.2	-0.1	-0.2	-2.5	-2.5	-2.5	0.0	-1.8	-2.5	-1.3	-1.2	-1.9	-1.4
Tense / ‘highly strung’	0.7	1.1	4.5	-1.6	1.5	-0.1	0.4	-2.1	-0.5	1.1	0.3	-0.8	-0.2	1.7	0.7	0.5	-0.5	1.3	-2.0	0.2	-0.8	-0.1
Mouth/teeth dental problems: Bleeding gums	0.7	0.8	4.7	0.2	0.5	-0.1	-1.3	-0.9	-2.2	1.4	0.8	-0.7	-0.2	0.8	-1.2	-0.9	-0.6	0.1	-0.4	-0.1	0.5	1.7
Glaucoma (self-reported)	0.7	0.8	4.8	-2.2	0.4	0.4	-1.5	-0.5	-0.1	0.7	-0.6	-1.4	-1.6	0.5	0.1	0.4	-1.3	0.0	0.0	0.2	0.3	-0.4
High blood pressure (siblings)	0.7	1.0	5.6	-1.6	-0.1	-0.4	-0.8	-0.0	0.6	-0.2	1.1	1.3	0.3	0.5	0.3	1.5	-0.9	1.4	-2.4	1.3	0.5	0.3
Number of full brothers	0.7	0.9	6.6	-2.3	0.3	-1.2	-0.5	-1.0	0.4	0.2	-0.1	-0.4	0.3	0.8	-0.3	-0.6	-1.2	0.4	-2.6	0.1	0.9	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	3.7	0.5	0.1	0.5	-0.2	0.4	-1.9	0.8	-0.6	0.8	-0.1	-0.3	0.5	0.9	0.9	0.1	1.2	0.3	1.7	-1.9
Age at last live birth	0.7	1.0	4.5	1.4	-0.8	0.7	0.3	1.6	-0.3	-0.6	0.1	0.1	0.4	-1.1	0.6	0.0	2.1	-1.3	0.1	-0.1	-1.7	-1.5
Illnesses of siblings: Diabetes	0.7	0.9	3.2	-1.8	0.4	-1.4	-1.2	-1.2	0.5	0.1	0.3	1.5	0.7	0.8	-0.5	0.9	-0.7	0.5	-1.7	0.2	1.0	0.7
Loneliness, isolation	0.7	0.9	3.6	-1.1	0.6	-1.1	-0.8	-1.2	-0.2	0.8	-1.6	-1.0	0.3	1.0	-0.4	-1.5	-1.2	0.5	-1.9	0.2	0.1	-0.6
Smoking status: Current	0.7	1.0	7.3	-2.7	0.1	-0.5	-0.2	-0.5	0.0	0.6	-1.0	-1.5	-0.8	0.6	0.1	-0.6	-1.7	0.3	-2.1	0.5	0.4	0.3
Guilty feelings	0.7	1.0	2.7	-1.6	0.3	-1.0	-0.9	-1.5	-0.1	0.6	-1.5	-0.5	-1.2	0.7	-0.7	-1.1	-1.1	0.2	-1.6	0.6	0.2	-1.6
Wears glasses or contact lenses	0.7	0.8	4.6	-1.7	-0.1	0.1	-0.8	0.4	0.4	0.0	-1.4	-0.3	-2.1	-0.4	-0.0	-1.3	-0.8	-1.1	-0.3	-0.4	-0.6	-1.0
Myopia	0.7	1.1	4.1	-1.4	0.7	-1.1	-1.1	-1.5	-0.0	1.1	-1.2	-1.5	-1.6	1.2	-0.2	0.9	-2.0	-0.4	-0.1	-0.3	0.7	0.6
Heart attack/myocardial infarction (self-reported)	0.7	0.9	4.6	-1.2	0.8	0.1	-0.6	-1.1	-1.3	1.5	-1.0	-1.0	-2.1	0.9	-0.0	0.8	-0.7	0.2	0.7	0.5	-0.4	-0.5
Bipolar Disorder (2018)	0.6	0.9	4.6	-0.9	-0.6	-1.0	0.1	-1.7	-0.2	0.2	-0.1	1.3	-1.2	-0.2	-1.5	-0.9	-1.1	-2.1	-0.4	-0.8	-0.5	-0.8
Reaction Time	0.6	1.2	4.5	-2.1	-0.8	-1.4	-0.0	-0.5	1.0	-0.5	-0.6	0.7	-0.1	-0.6	-1.7	0.3	-2.1	-1.6	-1.0	-1.5	-0.1	-0.9
Crohns Disease (2012)	0.6	0.9	3.8	0.1	-0.6	-1.5	-1.2	-0.8	-0.3	0.4	-1.9	-0.7	0.2	-0.1	-1.0	0.9	-1.7	-1.4	-0.7	-1.0	0.1	-1.2
HbA1C	0.6	0.7	2.3	-0.1	0.8	-0.2	-0.6	-0.6	-1.2	1.2	0.6	0.5	-0.5	0.5	-1.3	-1.5	-0.0	-0.7	1.3	-0.7	-0.3	1.4
Allergy or Eczema	0.6	1.7	5.0	0.7	1.8	2.2	-1.6	-1.6	-1.1	1.4	0.5	0.5	0.1	1.5	1.7	0.1	1.4	1.6	1.2	0.4	-0.8	1.9
Type 2 Diabetes (T2D) (2018)	0.6	1.1	3.7	-1.3	0.7	-0.7	0.8	-1.3	-1.3	1.6	-0.0	0.1	-1.0	1.3	-0.9	0.0	-1.9	0.8	-1.1	1.1	0.3	1.7
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	6.6	-0.7	-1.0	-1.4	-2.6	0.3	0.4	-0.4	0.2	0.2	-0.7	-0.7	-0.9	0.4	-1.5	-0.8	-0.4	-0.2	-0.8	-0.3
Ever had hysterectomy (womb removed)	0.6	0.7	3.3	-0.4	0.1	-0.7	-1.0	-1.2	-0.3	0.4	-1.3	-1.8	-0.6	0.4	-0.9	-0.1	-0.9	0.7	-1.3	-0.2	1.0	0.9
Medication: Metformin	0.6	0.8	2.7	-0.4	-0.8	-1.1	1.3	1.1	0.3	-0.2	0.5	-1.2	-1.4	-0.3	-1.0	0.4	-1.7	-0.0	-0.9	0.5	-0.4	1.6
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.3	-0.3	-1.3	-1.1	-0.2	0.6	0.7	-0.9	-0.1	-0.8	-0.7	-0.9	-0.8	0.6	-0.9	-0.4	-1.2	-0.3	1.3	1.5
Multivitamins +/- minerals	0.6	0.8	4.4	-0.5	0.5	1.4	1.0	0.7	0.3	-0.4	0.0	-0.5	0.9	0.1	1.1	0.4	2.1	1.2	-1.5	0.8	-0.3	-0.3
Chronic bronchitis/emphysema (father)	0.6	0.7	1.6	-0.6	0.6	1.0	-0.9	-0.3	-0.9	0.5	-1.0	-1.2	1.1	0.8	1.3	-0.8	0.5	1.0	-0.8	1.3	-0.7	0.1
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	3.8	-0.5	-0.6	-0.5	-1.2	0.2	0.2	0.0	-0.7	-1.1	-1.9	-0.6	-0.9	1.4	-1.1	-1.1	-0.9	-0.5	-0.4	0.1
Medication: Simvastatin	0.6	0.9	5.5	-2.1	0.3	0.3	-0.5	0.1	0.4	0.2	-0.7	-0.8	-1.5	0.6	0.2	0.1	-1.3	0.7	-2.3	0.6	-0.4	1.3
Father’s age at death	0.6	0.8	3.0	1.7	-0.2	0.5	1.7	0.7	0.3	-0.4	1.6	0.7	1.4	-0.1	0.7	-1.7	0.9	0.3	0.3	0.3	-0.9	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.6	-0.5	-0.9	0.2	-0.5	0.7	1.1	-1.0	-0.5	-1.2	-0.9	-1.2	-0.4	-0.2	-0.7	-0.5	-1.2	-1.3	-1.1	-0.3
Illnesses of mother	0.6	0.7	2.9	1.1	-0.7	-1.0	0.4	0.5	1.2	-1.5	0.7	0.6	0.3	-0.6	-0.6	0.8	-0.1	-0.8	0.1	-1.5	-1.7	-0.2
Blood clot in the leg (DVT)	0.6	0.8	3.8	-1.2	-0.7	-0.8	-0.6	0.5	0.9	-0.4	-0.9	-1.4	-1.3	-0.3	-0.0	-0.1	-1.6	-0.3	-1.9	0.0	0.3	0.2
Headache pain in last month	0.6	1.0	3.3	-1.8	1.0	0.1	-1.8	-1.7	0.0	0.7	-0.9	-0.3	-1.0	1.0	-0.3	-0.1	-0.9	1.1	-1.2	0.1	0.8	1.5
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	3.8	-1.7	-0.4	-1.9	0.3	-0.8	1.4	-0.5	-1.2	-0.4	-1.4	0.0	-0.8	0.0	-1.8	-1.2	-1.6	-0.9	0.6	-0.6
Had major operations	0.6	0.7	6.9	0.6	0.3	0.8	-0.8	0.4	-1.3	0.3	0.3	0.2	2.6	0.1	0.2	-0.0	1.5	0.4	0.2	0.4	-0.7	-0.1
Average weekly red wine intake	0.6	0.9	8.5	0.8	-0.7	-1.0	1.4	0.5	-0.6	-0.2	-0.7	0.4	-1.2	-0.7	-0.9	-0.8	0.0	-0.6	0.7	-0.7	0.2	-2.9
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.2	-0.2	0.4	-0.4	-1.4	-1.5	-1.0	0.7	0.8	0.6	0.0	0.4	-1.1	-0.1	-0.9	0.5	0.6	-0.8	1.1	0.7
Medication: Aspirin	0.6	0.8	3.5	-1.3	-0.0	-0.2	-1.1	-0.0	-0.1	0.3	-1.5	-1.9	-1.1	-0.2	-0.4	1.8	-0.8	0.0	-1.2	-0.7	-0.1	0.2
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.3	-1.3	0.6	0.9	0.5	-0.3	0.2	0.1	-1.4	-1.8	0.3	0.8	0.8	0.2	0.6	1.0	-1.7	0.8	0.6	-0.0
High cholesterol (Self-reported)	0.6	1.0	5.3	-1.4	0.6	0.8	-0.5	-0.1	0.9	0.2	-0.0	-1.2	-2.0	0.8	-0.0	-0.2	-1.1	0.6	-1.7	-0.0	0.4	2.3
Unable to work because of sickness or disability	0.6	0.8	3.2	-0.7	0.6	0.4	-1.8	-0.7	-0.9	0.9	0.0	0.2	-0.1	1.3	0.8	-1.3	-0.3	0.8	-1.3	0.9	1.2	0.9
Pack years of smoking	0.6	0.8	6.2	-0.9	-0.0	0.9	-1.2	0.8	0.5	-0.7	0.7	0.1	-0.5	-0.4	-0.3	-1.3	0.3	0.4	-0.5	-0.7	-2.5	1.5
Rheumatoid Arthritis	0.5	0.8	2.5	0.3	0.9	0.0	0.8	-0.8	0.1	0.3	1.6	1.6	0.7	1.3	0.6	0.4	0.2	1.2	-1.3	0.7	-0.2	1.2
Pack years adult smoking proportion	0.5	0.8	5.3	-0.8	0.3	1.1	-1.0	0.4	0.2	-0.4	0.9	-0.2	-0.4	0.0	0.1	-1.1	0.4	0.8	-0.5	-0.4	-2.3	1.9
Hand grip strength (right)	0.5	1.5	7.2	0.8	1.0	1.1	2.3	0.5	0.8	-0.2	0.6	-0.9	0.0	1.2	2.7	0.5	1.6	1.4	-0.9	1.9	-0.4	1.2
Relative age voice broke	0.5	0.7	3.7	1.9	-0.0	0.1	-0.2	-0.1	-1.4	0.4	0.3	1.5	1.2	-0.3	-0.7	-0.4	0.8	0.1	1.4	0.3	-1.4	-0.4
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.7	-0.7	-0.8	-0.9	0.0	0.7	-0.2	-0.5	-0.5	-0.3	-1.0	-0.8	-1.3	-0.9	-0.9	-0.3	-1.3	-0.2	0.7	-0.4
Hayfever, allergic rhinitis or eczema	0.5	1.1	8.3	0.3	1.1	1.7	-1.0	-1.0	-0.6	1.0	0.5	-0.4	-0.0	0.8	1.4	0.5	1.1	1.0	0.5	0.8	-0.6	2.9
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	3.6	1.2	-0.7	0.4	0.3	1.9	0.6	-0.8	0.7	-0.4	0.3	-1.0	0.2	0.3	0.5	-0.0	-0.1	-0.6	-1.6	0.6
Body mass index (BMI)	0.5	2.2	7.1	-0.8	-2.0	-2.7	-0.3	1.1	1.7	-2.1	-0.8	-1.2	-1.1	-1.5	-2.1	-0.5	-1.6	-1.3	-2.5	-1.0	-1.1	-0.1
Pulse rate	0.5	0.9	4.0	-0.3	0.8	0.4	1.5	-0.4	-1.1	0.5	0.8	-0.5	2.0	0.7	-0.0	-1.4	1.4	0.8	0.1	1.0	1.1	0.1
Mouth/teeth dental problems: Dentures	0.5	0.9	6.2	-2.5	1.1	0.6	-0.6	-0.8	-0.1	0.8	-0.3	0.0	-2.0	1.2	0.7	-0.7	-0.5	0.5	-1.1	0.2	-0.1	-0.3
Medication: Cholesterol lowering	0.5	0.8	4.4	-0.6	0.9	0.9	-1.4	-0.4	-0.2	1.0	-0.3	-0.7	-1.5	0.7	-0.1	0.6	-0.8	1.1	-0.6	-0.6	-0.6	2.1
Medication: Lansoprazole	0.5	0.6	3.1	-1.3	-0.1	-0.1	-1.8	-0.8	-0.5	0.4	-0.1	-0.8	-1.5	0.2	-0.4	-1.3	-0.8	-0.3	-0.3	0.4	-0.0	-0.4
Impedance of arm (left)	0.5	2.4	7.9	1.5	1.6	2.1	-1.2	-1.6	-2.0	2.3	2.5	2.8	0.6	1.2	0.7	-0.0	0.4	1.2	2.4	0.6	0.6	1.4
Migraine (self-reported)	0.5	0.6	2.9	-0.5	-0.7	-0.5	0.3	0.4	0.5	-0.3	-0.8	-0.2	-1.5	-0.6	-0.8	0.8	-1.6	-0.4	-1.7	-0.5	-1.0	-0.3
Medication: Seretide 50 evohaler	0.5	0.6	3.6	-1.9	0.0	-0.5	-0.2	-0.1	0.6	0.3	-0.4	-1.7	-0.2	0.2	-0.2	-0.4	-1.5	-0.0	-0.7	0.2	-0.6	0.7
Leg fat mass (right)	0.5	1.9	4.6	-0.9	-1.7	-2.1	-1.6	0.3	0.8	-1.4	-0.0	-0.8	-1.9	-1.3	-2.1	-0.6	-1.7	-1.2	-2.2	-0.9	-1.8	0.7
Suffer from ‘nerves’	0.5	0.8	3.8	-1.5	0.2	-0.8	-1.7	-0.6	1.0	-0.3	-0.2	-0.1	-1.1	0.6	-0.3	1.2	-0.9	-0.5	-1.9	-0.4	-0.3	0.4
Knee pain experienced in last month	0.5	0.8	5.3	-2.3	0.7	0.6	-1.2	-1.0	-0.3	0.8	-0.1	-1.0	-1.3	0.7	-0.3	0.1	-0.9	0.4	-1.6	-0.7	-0.2	-0.4
Eye problems/disorders: Cataract	0.5	0.6	3.7	-0.6	0.5	0.5	0.1	0.1	0.4	-0.0	-0.5	-0.1	0.9	0.8	1.9	-0.0	1.0	1.0	-0.5	1.6	0.6	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	7.4	-0.7	0.1	0.2	1.0	0.3	0.0	-0.3	0.3	-1.5	0.3	0.4	0.5	0.5	0.7	0.6	-2.7	0.3	-0.0	1.3
Mineral and other dietary supplements	0.5	0.7	3.4	1.2	-0.3	-0.1	-0.1	1.2	-0.7	0.1	1.8	1.8	0.9	-0.5	-0.5	0.3	0.4	-0.0	1.0	0.1	-1.1	0.3
Arm fat mass (left)	0.5	2.1	6.7	-0.6	-2.2	-2.3	-0.8	1.2	1.2	-1.9	-0.4	-0.8	-1.4	-1.7	-2.1	-0.7	-1.5	-1.4	-2.6	-0.6	-1.8	0.3
Hearing aid user	0.5	0.6	2.5	-1.6	0.6	0.6	1.2	-0.7	-1.0	1.1	-0.5	-1.0	-0.1	0.8	0.8	0.3	-0.8	0.5	-0.4	0.4	0.7	0.9
Mother’s age at death	0.5	0.6	3.3	1.2	-0.8	-0.2	1.1	0.2	-0.1	-0.4	1.3	0.7	-0.5	-0.7	0.0	-0.2	-0.4	-0.6	1.8	0.0	0.9	-1.4
Commuting to job workplace: Public transport	0.5	0.6	1.7	1.2	-0.9	-0.2	0.6	1.2	0.5	-0.9	1.1	1.3	-0.2	-1.0	0.1	1.3	-0.2	-0.4	-0.3	-0.6	-0.9	0.2
Medication: Bendroflumethiazide	0.5	0.8	3.0	0.2	0.8	0.9	0.6	0.3	-0.0	0.4	-0.6	0.4	1.7	0.9	1.0	-1.0	1.2	1.4	-0.4	1.5	1.1	0.1
Alcohol drinker status: Never	0.5	0.6	2.3	-0.5	-1.1	0.4	-0.0	1.2	1.1	-1.5	-0.2	0.5	0.9	-1.2	-0.4	0.6	-0.0	-1.2	-0.9	-0.5	0.2	0.5
Risk taking	0.5	0.8	3.3	1.3	0.8	0.2	0.6	-0.3	-0.9	1.0	0.7	-0.0	0.3	0.6	0.2	-1.6	0.5	1.7	1.8	0.2	-0.2	0.4
Leg fat mass (left)	0.5	1.9	5.0	-1.0	-1.8	-2.2	-1.5	0.4	0.9	-1.5	-0.3	-1.0	-1.8	-1.3	-2.2	-0.7	-1.7	-1.3	-2.1	-0.9	-1.7	0.4
HDL Cholesterol	0.4	0.7	2.4	-0.6	-0.8	-1.0	-0.6	0.0	-0.1	0.3	0.5	-0.1	-1.6	-0.7	-1.0	-0.6	-1.3	-1.1	1.4	-0.2	-0.4	-1.2
Lupus	0.4	0.6	4.7	-2.2	0.5	0.2	1.7	-0.5	-0.2	0.4	-1.1	-0.4	-0.5	0.1	-0.1	-0.9	-0.2	0.4	-0.9	0.4	0.2	-0.4
Blood Eosinophil Count	0.4	3.3	15.5	-0.3	2.9	0.2	-3.9	-3.9	-1.7	3.0	0.4	2.7	0.1	2.4	-0.1	0.1	0.3	0.4	0.6	-1.2	0.2	-0.9
Blood White Count	0.4	2.7	10.5	-3.2	0.0	-1.9	1.1	-1.9	0.5	0.4	-2.2	-1.2	-2.0	0.6	-1.1	-2.5	-2.4	-1.3	-1.9	-1.4	1.2	-1.7
Vitamin and mineral supplements	0.4	0.5	2.4	1.1	-0.4	-0.8	-0.1	-0.1	-0.3	0.1	0.8	1.5	0.1	-0.4	-0.9	0.0	-0.8	-0.9	1.6	-0.8	-0.1	-0.5
Diabetes (mother)	0.4	0.5	2.4	-0.4	-0.2	0.8	-0.3	0.3	-0.1	-0.2	1.5	-0.1	1.2	-0.0	0.6	-1.5	0.6	0.4	-0.3	0.6	-0.8	0.9
Leg fat-free mass (left)	0.4	2.1	5.8	0.3	-2.4	-2.4	0.2	1.7	0.7	-1.8	0.3	-0.8	-1.8	-2.1	-1.9	-0.0	-0.9	-1.6	-1.9	-0.1	-2.1	-0.3
Average weekly fortified wine intake	0.4	0.4	1.2	-0.6	0.5	-0.5	-0.5	-0.8	-0.5	0.7	-1.1	-0.8	-0.3	0.6	0.2	-1.0	-0.5	0.6	0.6	0.8	1.0	-0.8
Stomach or abdominal pain in last month	0.4	0.5	2.0	-1.3	0.5	-0.7	-0.3	-1.1	-0.3	0.7	0.7	-0.6	-0.9	0.8	-0.3	1.4	-1.2	0.4	-0.5	-0.1	-0.0	0.4
Medication: Atenolol	0.4	0.5	2.5	-0.1	-0.6	-0.6	-0.2	0.1	0.4	-0.2	-0.8	-1.3	-1.2	-0.3	-0.3	1.6	-1.0	-0.6	-0.4	-0.3	-0.7	0.2
Leg predicted mass (left)	0.4	2.2	6.2	0.3	-2.5	-2.4	0.1	1.7	0.8	-1.9	0.3	-0.8	-1.8	-2.2	-1.9	-0.0	-0.9	-1.6	-2.0	-0.2	-2.1	-0.2
Trunk fat mass	0.4	1.7	4.6	-0.6	-1.7	-2.1	-1.1	0.3	0.8	-1.3	0.1	-0.4	-1.9	-1.3	-2.1	-0.8	-1.9	-1.2	-2.1	-0.7	-1.7	0.3
Diabetes (self-reported)	0.4	0.6	2.7	-1.2	-0.5	-0.9	-0.6	0.3	-0.1	0.1	0.0	-0.3	-0.3	-0.1	-1.2	-0.6	-1.2	0.4	-1.0	0.8	-0.3	1.6
Impedance of arm (right)	0.4	2.0	5.5	1.5	1.6	2.0	-0.6	-1.6	-1.9	2.2	1.7	2.3	0.8	1.2	0.8	-0.2	0.4	0.9	2.0	0.3	0.3	1.7
Arm fat percentage (right)	0.4	1.7	5.8	-0.8	-1.7	-2.1	-1.4	0.7	1.1	-1.4	-0.4	-0.3	-0.9	-1.1	-1.9	-1.1	-1.6	-1.1	-2.4	-0.7	-1.4	0.6
Hair/balding pattern: Pattern 3	0.4	0.6	3.2	-1.2	-0.6	-0.7	0.4	0.3	1.5	-1.2	0.1	-0.3	0.9	0.0	0.4	-0.4	-0.2	-1.0	-1.8	-0.1	-0.3	0.9
Arm fat mass (right)	0.4	1.7	6.0	-0.4	-1.9	-2.2	-0.7	0.9	1.0	-1.6	-0.2	-0.9	-1.0	-1.4	-1.9	-0.8	-1.5	-1.2	-2.4	-0.5	-1.7	0.7
Birth weight of first child	0.4	0.8	2.7	1.1	0.2	0.9	1.1	0.5	-0.6	-0.1	0.6	0.8	0.8	-0.4	-0.1	-1.0	1.6	0.5	1.6	0.7	1.6	-1.0
Pulse wave reflection index	0.4	0.5	2.3	-1.2	0.2	0.1	0.9	-0.2	0.5	0.2	-0.5	-0.5	-0.3	0.4	0.1	-0.3	-1.5	0.7	-1.3	0.7	0.6	0.6
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.6	0.6	1.2	-0.1	-0.4	-1.1	-0.3	1.1	-1.2	-0.8	-0.2	1.0	0.1	-1.2	-0.2	0.9	0.2	-0.3	-0.9	-0.0
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.3	1.1	-1.0	-1.0	0.2	0.3	0.6	-1.2	0.5	0.6	0.7	-0.9	-0.1	-1.5	0.6	-1.5	0.9	-0.6	0.3	-0.6
Medication: Amlodipine	0.4	0.6	5.5	0.1	0.2	-0.6	-2.3	-1.0	-0.8	0.6	-0.5	0.1	0.2	0.0	-1.0	0.7	-0.6	-0.4	0.5	-0.2	-0.7	0.3
Medication: Ventolin 100micrograms inhaler	0.4	0.5	3.0	-1.5	0.5	-0.3	-0.2	-0.9	0.5	0.6	-1.2	-1.7	-0.8	0.2	0.3	0.2	-0.4	-0.5	-0.4	-0.3	-0.5	0.4
Comparative body size at age 10	0.4	1.0	3.9	1.2	-1.1	-0.1	0.6	1.6	0.8	-1.4	0.1	0.7	0.9	-0.9	-0.2	0.9	1.3	-0.0	-2.0	1.6	0.3	0.4
Whole body fat mass	0.4	1.9	5.5	-0.7	-1.9	-2.2	-1.2	0.5	0.9	-1.4	0.1	-0.7	-1.7	-1.4	-2.1	-0.6	-1.9	-1.2	-2.3	-0.6	-1.7	0.5
Leg pain on walking	0.4	0.5	3.0	-0.8	0.3	0.4	0.5	0.8	0.7	-0.4	-0.6	0.0	-0.6	0.1	-0.2	1.7	0.6	0.6	-1.2	0.2	1.2	-0.4
Leg fat-free mass (right)	0.4	1.9	5.7	0.2	-2.4	-2.3	0.3	1.8	0.8	-1.8	0.1	-0.6	-1.6	-2.1	-1.8	-0.1	-0.8	-1.5	-1.8	0.1	-1.8	-0.4
Arm fat percentage (left)	0.4	1.8	5.4	-0.6	-1.9	-2.1	-1.5	0.9	1.3	-1.6	-0.1	-0.3	-1.1	-1.3	-2.0	-0.7	-1.8	-1.1	-2.3	-0.7	-1.4	0.4
Medication for cholesterol	0.4	0.7	1.5	0.7	0.8	1.2	0.9	-0.3	-1.1	0.9	0.9	0.4	1.2	0.5	0.3	-0.2	1.2	0.8	1.0	1.2	-0.0	0.4
Illnesses of father: None of the above (group 1)	0.4	0.4	2.4	0.1	0.5	-0.3	-0.1	-1.1	-0.1	0.3	-0.9	-0.9	-1.6	0.4	-0.8	0.4	-0.4	-0.5	0.6	-1.0	0.1	0.8
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.0	-1.4	-0.1	-0.2	-0.3	-0.1	0.1	-0.1	-1.4	-0.8	0.3	-0.0	-0.3	-0.3	-0.7	-0.2	-0.6	0.4	1.2	-1.2
Fractured/broken bones in last 5 years	0.4	0.5	2.4	0.3	-0.1	-1.1	-0.3	-1.6	-0.6	0.6	-0.8	-0.4	-0.5	-0.1	-0.9	-0.9	-1.1	-0.6	-0.2	-1.0	0.4	-0.4
Commuting to job workplace: Cycle	0.4	0.5	2.1	-0.1	0.3	-0.0	1.5	-0.3	1.2	-0.4	0.1	-0.1	1.3	0.7	0.7	1.4	0.0	0.3	0.2	-0.2	0.0	0.8
Vascular/heart problems diagnosed by doctor	0.4	1.2	3.8	0.1	-1.6	-0.8	0.0	0.9	1.5	-1.7	0.7	0.1	0.5	-1.9	-1.0	-1.0	-0.2	-1.5	1.0	-2.0	-0.8	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	3.4	-0.9	-0.7	-0.5	-0.5	0.7	0.7	-0.4	-0.4	-1.2	-1.2	-0.3	0.1	-0.3	-1.1	-0.3	-1.9	0.1	0.2	0.5
Alzheimer’s Disease (including proxy)	0.3	0.4	1.8	-0.8	-0.3	-0.2	-0.9	-0.2	-0.4	0.5	0.4	0.2	-0.5	-0.3	-0.2	0.8	-1.4	0.4	-1.2	0.7	0.6	0.3
Irritable Bowel Disease (IBD)	0.3	0.7	3.0	0.1	0.8	1.1	0.9	-0.2	-0.7	1.1	-0.5	0.8	0.1	1.2	0.9	0.4	-0.2	0.7	-1.2	1.2	1.7	-0.9
Triglycerides	0.3	0.4	2.7	1.1	-0.2	-0.8	-0.7	-0.2	-0.3	0.0	0.0	1.0	0.8	0.2	0.2	0.9	0.1	-0.5	0.5	0.5	1.6	0.1
Hypothyroidism (self reported)	0.3	0.8	2.8	-1.4	0.0	-0.9	1.3	-0.8	1.3	-0.6	-0.8	0.3	-0.9	0.1	-0.2	-0.3	-0.4	-0.6	-1.2	-0.1	1.2	-1.7
Lung FEV1/FVC ratio	0.3	1.8	20.2	-0.3	0.1	-0.3	4.5	0.5	1.6	-1.1	0.4	1.3	1.4	0.5	0.6	-0.7	1.1	0.4	-0.7	1.0	0.0	1.7
Hand grip strength (left)	0.3	0.8	2.8	0.5	0.4	0.5	1.6	0.6	0.7	-0.4	1.1	0.3	-1.2	0.5	1.7	0.6	0.9	1.0	-1.0	1.1	-0.7	0.5
Trunk fat percentage	0.3	1.4	4.8	-0.7	-1.3	-1.8	-1.5	-0.2	0.7	-0.9	0.3	0.2	-1.5	-1.0	-2.2	-0.9	-2.0	-1.0	-1.5	-0.8	-1.1	0.4
High blood pressure	0.3	0.9	2.8	0.3	1.4	0.7	0.3	-0.9	-1.5	1.4	-0.5	0.4	-0.0	1.7	0.8	0.0	0.4	1.4	-0.8	1.6	0.9	0.1
Waist circumference	0.3	1.2	3.1	0.2	-1.8	-1.7	-0.8	1.3	0.6	-1.4	0.2	-0.6	-1.2	-1.2	-1.6	-0.7	-1.1	-0.8	-1.8	0.1	-0.8	0.6
Number of incorrect matches in round	0.3	0.4	2.9	-0.4	-0.1	0.1	0.3	0.4	0.2	-0.2	0.3	-0.2	0.9	0.2	0.8	-0.4	-0.0	0.3	-1.5	0.0	-1.7	1.1
Nervous feelings	0.3	0.6	4.8	-0.8	0.9	0.1	-0.7	-1.4	-0.3	0.4	-0.0	0.4	-0.1	1.2	0.7	0.1	-0.1	0.5	-2.2	0.5	-0.2	0.5
Weight	0.3	1.6	5.2	-0.2	-2.0	-2.3	-0.1	0.9	0.8	-1.6	0.2	-0.6	-1.8	-1.4	-1.6	-0.6	-1.4	-1.2	-2.1	-0.1	-1.6	0.2
Trunk fat-free mass	0.3	1.4	3.5	0.0	-1.9	-1.7	1.5	1.5	0.6	-1.6	0.3	-1.3	-1.3	-1.6	-0.9	0.3	-0.2	-1.3	-1.7	0.1	-1.9	-0.2
Time employed in main current job	0.3	0.3	2.0	0.7	-0.7	0.5	0.7	0.3	-0.4	-0.3	0.2	1.4	-0.8	-0.5	0.3	-0.1	0.4	-0.8	0.3	0.4	-0.3	-0.6
Trunk predicted mass	0.3	1.5	3.7	0.0	-1.9	-1.7	1.5	1.5	0.6	-1.6	0.3	-1.3	-1.2	-1.6	-0.9	0.3	-0.1	-1.3	-1.7	0.0	-1.9	-0.1
Birth weight	0.3	0.6	2.6	0.6	0.6	0.6	1.6	-0.1	-0.4	0.8	1.6	0.5	0.7	0.0	0.3	0.9	0.2	0.7	0.6	0.2	1.1	1.3
Body fat percentage	0.3	1.3	3.7	-0.8	-1.2	-1.8	-1.6	-0.2	0.7	-0.9	0.1	-0.2	-1.4	-0.7	-1.9	-0.9	-1.9	-0.8	-1.7	-0.7	-1.0	0.6
Leg fat percentage (right)	0.3	1.1	3.1	-1.4	-0.5	-1.3	-1.7	-0.8	0.5	-0.5	0.1	-0.4	-1.6	-0.1	-1.5	-0.8	-1.7	-0.4	-1.5	-0.8	-1.0	1.0
Arm fat-free mass (right)	0.3	1.4	4.0	-0.0	-2.0	-2.0	0.5	1.4	0.5	-1.7	-0.1	-1.3	-1.5	-1.7	-1.5	0.2	-0.3	-1.3	-1.6	0.1	-1.3	-0.8
Arm predicted mass (right)	0.3	1.4	4.1	-0.1	-1.9	-2.0	0.7	1.2	0.7	-1.6	0.1	-1.3	-1.7	-1.6	-1.4	0.1	-0.6	-1.3	-1.4	0.0	-1.4	-0.8
Whole body fat-free mass	0.3	2.0	5.7	0.3	-2.4	-2.1	1.1	1.8	0.7	-1.9	0.2	-1.2	-1.5	-2.1	-1.5	0.2	-0.5	-1.6	-1.8	-0.0	-1.9	-0.4
Diabetes diagnosed by doctor	0.3	0.6	4.1	-0.2	0.2	-0.6	0.1	-0.3	-0.8	0.9	0.5	-0.3	-0.7	0.7	-0.7	-0.0	-1.2	0.8	-0.7	1.0	-0.2	2.0
Whole body water mass	0.3	1.6	4.6	0.2	-2.1	-2.0	1.2	1.6	0.6	-1.7	0.2	-1.2	-1.3	-1.8	-1.3	0.2	-0.3	-1.4	-1.8	0.1	-1.7	-0.4
Leg predicted mass (right)	0.3	1.8	5.4	0.3	-2.3	-2.2	0.4	1.8	0.7	-1.8	0.2	-0.6	-1.5	-2.0	-1.7	-0.1	-0.8	-1.4	-1.9	0.1	-1.8	-0.3
Basal metabolic rate	0.3	1.6	4.5	0.2	-2.0	-2.1	0.7	1.3	0.6	-1.6	0.3	-1.0	-1.4	-1.7	-1.4	-0.1	-0.6	-1.3	-1.9	0.1	-1.9	-0.1
Leg fat percentage (left)	0.3	1.1	3.2	-1.5	-0.6	-1.3	-1.6	-0.7	0.6	-0.6	-0.2	-0.4	-1.5	-0.2	-1.6	-0.9	-1.8	-0.5	-1.4	-0.8	-0.7	0.8
Arm fat-free mass (left)	0.3	1.4	4.7	0.0	-1.9	-2.2	1.0	1.0	0.5	-1.5	-0.2	-1.3	-1.5	-1.6	-1.4	0.1	-0.5	-1.4	-1.5	-0.3	-1.3	-0.5
Basal cell carcinoma (self-reported)	0.3	0.3	1.7	-0.6	-0.1	-0.6	0.0	0.2	0.0	0.1	1.3	1.0	0.2	0.2	-0.5	-0.4	-1.0	0.5	0.1	0.2	1.0	-0.7
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.7	-0.1	0.6	0.9	0.4	-0.3	-0.7	0.6	0.2	-0.2	-0.7	0.6	0.4	0.2	0.5	0.2	-0.8	0.5	0.7	-0.1
Blood Red Count	0.2	1.7	4.0	-0.9	-2.0	-0.7	-0.8	1.7	1.2	-2.0	0.0	-0.6	-1.0	-2.0	-1.6	-1.3	-0.3	-1.2	-2.0	-1.3	-0.4	-1.8
Cardiovascular Disease	0.2	0.6	1.7	-0.4	1.1	1.1	-0.5	-0.5	-0.6	1.0	-0.5	-0.5	-0.6	1.3	0.6	0.3	0.4	1.3	-1.1	1.3	0.4	0.6
Systolic blood pressure, automated reading	0.2	0.5	3.6	-0.2	0.2	0.5	1.0	-0.3	0.0	-0.1	-0.1	0.4	-1.9	0.1	0.1	-0.9	0.9	-0.3	0.4	0.2	0.3	-1.9
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	1.5	-0.0	-0.3	-0.2	-0.8	-0.0	-0.3	0.3	0.1	0.2	-0.5	-0.2	-0.5	-0.4	-0.7	-0.1	1.2	0.1	0.7	-0.0
Supplements: Zinc	0.2	0.3	0.9	0.9	0.5	0.6	0.3	-0.4	-0.5	0.3	-0.5	-0.1	-1.0	0.2	0.0	0.8	0.6	0.1	0.3	-0.5	0.6	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.2	-0.8	-0.0	-1.0	-1.2	-0.4	0.3	0.1	1.2	-0.6	-0.1	0.1	-0.5	-0.6	-1.0	0.4	-1.0	-0.4	-0.2	1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	2.5	-0.6	-0.1	-0.9	-0.8	-0.7	0.1	0.2	1.6	-0.1	-0.3	-0.2	-1.1	-0.6	-1.1	0.3	-0.8	-0.8	-0.1	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.2	0.1	-0.6	-0.5	0.6	0.3	-0.3	-0.1	-0.0	0.6	0.9	0.0	-0.3	0.0	-0.3	0.4	-1.0	1.1	0.3	-0.2
Pulse rate, automated reading	0.2	0.7	4.0	-1.6	-0.1	-0.7	0.2	-0.3	-0.6	0.2	-0.7	-2.0	0.8	0.1	-1.6	-1.1	-0.7	0.3	-0.3	-0.2	0.5	0.1
Hypertension (Self-reported)	0.2	0.6	2.2	0.3	1.2	0.5	0.1	-0.6	-1.1	1.1	-0.4	0.3	0.2	1.4	0.6	-0.2	0.4	1.2	-0.8	1.5	0.8	-0.2
Illnesses of father: Heart disease	0.2	0.3	1.1	-0.3	-0.5	-0.8	-0.5	0.7	-0.2	0.4	-0.8	-0.7	0.1	-0.1	-0.2	0.4	-1.1	-0.1	-0.3	0.6	0.6	0.2
Medication: Blood pressure	0.2	0.3	1.5	0.4	-0.3	0.1	-0.7	1.1	0.7	-0.8	-0.9	-0.4	-0.4	-0.3	0.5	0.3	0.7	0.1	-1.2	0.1	-0.0	-0.3
Medication: Lisinopril	0.2	0.3	1.4	0.2	0.2	0.8	-1.2	0.0	-0.8	0.6	0.2	0.1	-0.9	0.1	-0.0	0.1	0.0	0.3	-0.8	1.0	0.5	0.4
Diastolic blood pressure, automated reading	0.2	0.7	2.5	-1.4	0.4	-0.3	1.6	-1.5	-0.5	0.4	-0.1	-0.2	-0.7	0.9	-0.2	-1.2	-0.7	0.8	-0.7	1.1	0.6	-0.6
Arm predicted mass (left)	0.2	1.0	3.5	-0.1	-1.5	-1.9	0.9	0.9	0.5	-1.3	-0.0	-1.4	-1.2	-1.2	-0.9	-0.3	-0.3	-1.1	-1.5	0.2	-1.2	-0.4
Blood Platelet Count	0.1	0.8	3.3	-0.9	0.9	0.3	0.8	-1.8	-0.4	0.6	-1.2	-0.9	-0.3	1.0	0.1	-0.7	-0.4	1.1	-0.9	-0.0	1.4	-1.1
Heel T-Score	0.1	0.7	2.7	1.1	-0.2	-0.5	-0.8	-0.2	-0.7	0.5	1.0	-0.5	-1.0	-0.0	-0.7	-1.6	-0.8	0.6	0.6	-1.2	0.5	1.3
Height	0.1	1.8	12.5	0.7	-1.1	0.4	-0.5	0.8	0.4	-0.7	2.3	0.6	-2.5	-1.3	0.3	-0.6	-0.2	-1.0	0.8	-0.0	-3.5	2.1
Relative age of first facial hair	0.1	0.3	1.3	0.6	-0.4	-0.1	-0.7	0.1	-0.8	0.2	0.9	-0.3	-0.4	-0.5	-0.4	0.6	-0.2	0.0	0.4	0.4	-1.1	0.2
Sitting height	0.1	0.5	6.2	0.0	0.1	0.1	-0.7	-0.9	-0.7	0.7	1.0	0.0	-2.5	0.2	0.3	0.4	-0.7	-0.0	0.1	0.3	-0.3	0.5
Standing height	0.1	1.3	6.2	1.6	-0.1	0.7	0.6	-0.2	-2.0	1.0	2.5	1.1	-1.6	-0.2	0.7	-0.4	0.6	0.1	1.2	1.7	-1.1	0.7
Osteoporosis (self-reported)	0.1	0.2	1.5	-0.4	-0.1	-0.1	0.2	-0.4	-0.2	0.0	-0.1	-0.6	0.4	0.4	0.2	0.4	-0.0	0.1	-1.2	0.6	-0.2	0.2
Hair Pigment	0.0	1.1	2.9	-1.1	-1.6	-1.2	0.7	1.2	1.6	-1.7	-1.4	-0.9	-0.3	-1.2	-0.5	0.1	-0.4	-1.4	-0.7	-0.3	-0.7	-0.7
Tanning	0.0	0.6	2.3	-0.3	0.4	0.7	1.2	0.5	0.0	0.2	0.1	-1.0	1.2	0.9	1.5	0.4	0.1	0.3	-0.9	1.4	1.1	0.2
Comparative height size at age 10	0.0	0.3	1.0	0.7	-1.0	-0.3	0.4	0.1	-0.3	-0.2	-0.0	-0.3	-0.8	-0.9	0.0	-0.4	-0.0	-0.9	-0.5	0.5	0.0	-0.4

Hub : Genes

SDK1

Models

Trait associations