Best TWAS P=3.37e-08 · Best GWAS P=1.73e-10 conditioned to 0.000199
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ATXN2 | 0.02 | 0.03 | enet | 8 | 0.02 | 4.8e-04 | -3.7 | 5.3 | 9.1e-08 | 0.57 | 0.25 | 0.66 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | ALDH2 | 0.10 | 0.09 | enet | 13 | 0.13 | 6.7e-11 | -4.2 | 5.5 | 3.4e-08 | 0.64 | 0.86 | 0.14 | TRUE |
| 3 | GTEx | Stomach | TMEM116 | 0.13 | 0.03 | lasso | 7 | 0.03 | 1.6e-02 | -3.9 | -5.1 | 2.6e-07 | -0.48 | 0.06 | 0.19 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ACAD10 | 0.02 | 0.02 | lasso | 3 | 0.01 | 7.0e-03 | -5.2 | -5.2 | 1.8e-07 | -0.52 | 0.00 | 0.86 | FALSE |