[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr17:79,202,465-80,694,826

Best TWAS P=7.35e-16 · Best GWAS P=1.51e-14 conditioned to 0.103

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	YFS	Blood	ASPSCR1	0.11	0.07	lasso	9	0.06	7.9e-20	-7.6	8.1	7.4e-16	-0.85	0.00	1.00	TRUE
4	GTEx	Adipose Subcutaneous	LRRC45	0.23	0.06	lasso	3	0.05	1.0e-04	-6.9	7.3	3.6e-13	-0.75	0.27	0.68	FALSE
6	GTEx	Artery Tibial	LRRC45	0.09	0.07	lasso	4	0.04	2.0e-04	-6.9	7.3	3.6e-13	-0.76	0.28	0.66	FALSE
9	GTEx	Heart Atrial Appendage	LRRC45	0.19	0.06	enet	9	0.12	6.7e-06	-6.0	7.2	4.8e-13	-0.79	0.30	0.60	FALSE
7	GTEx	Cells Transformed fibroblasts	LRRC45	0.08	0.08	enet	3	0.08	2.6e-06	-6.9	7.2	7.8e-13	-0.81	0.17	0.82	FALSE
20	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LRRC45	0.10	0.02	blup	35	0.04	8.0e-03	-5.1	7.2	8.9e-13	-0.76	0.01	0.43	FALSE
11	GTEx	Thyroid	ASPSCR1	0.23	0.15	enet	19	0.09	1.2e-07	-6.4	7.0	2.0e-12	-0.74	0.74	0.26	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LRRC45	0.02	0.03	blup	36	0.02	1.5e-03	-6.9	7.0	2.3e-12	-0.80	0.02	0.62	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	STRA13	0.05	0.03	lasso	3	0.02	1.8e-03	-6.9	6.9	4.4e-12	-0.75	0.08	0.46	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	LRRC45	0.05	0.07	lasso	6	0.06	9.5e-08	-6.9	6.9	5.5e-12	-0.81	0.08	0.92	FALSE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PYCR1	0.02	0.01	blup	9	0.01	1.1e-02	-6.3	6.9	6.0e-12	-0.68	0.00	0.66	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	MYADML2	0.03	0.03	blup	10	0.03	1.1e-04	-6.8	-6.8	1.2e-11	0.69	0.02	0.89	FALSE
2	CommonMind	Brain Pre-frontal Cortex	LRRC45	0.09	0.10	enet	7	0.10	1.2e-11	-6.9	6.7	2.7e-11	-0.73	0.41	0.59	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	NOTUM	0.06	0.02	enet	2	0.02	4.7e-03	-5.2	-6.4	1.2e-10	0.63	0.01	0.56	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	DCXR	0.09	0.03	blup	38	0.09	9.5e-09	3.6	6.4	1.5e-10	-0.49	0.27	0.72	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DCXR	0.14	0.07	enet	17	0.10	3.4e-12	3.4	6.4	1.7e-10	-0.43	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	MYADML2	0.52	0.43	enet	15	0.45	3.6e-60	-6.3	-6.3	3.3e-10	0.59	0.97	0.03	FALSE
5	GTEx	Adipose Visceral Omentum	LRRC45	0.18	0.03	enet	12	0.10	9.0e-06	-6.8	6.0	1.7e-09	-0.75	0.42	0.52	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	NPB	0.03	0.01	enet	3	0.01	1.1e-02	-6.2	5.8	9.0e-09	-0.64	0.00	0.69	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	DCXR	0.12	0.00	enet	13	0.00	2.3e-01	3.6	5.6	2.3e-08	-0.42	0.08	0.15	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	STRA13	0.05	0.04	blup	33	0.05	5.0e-06	-6.9	5.2	1.8e-07	-0.72	0.18	0.82	FALSE
8	GTEx	Esophagus Muscularis	DCXR	0.18	0.08	lasso	5	0.05	9.2e-04	3.9	5.2	2.2e-07	-0.30	0.62	0.12	FALSE