Best TWAS P=3.29e-08 · Best GWAS P=1.65e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | TSPY26P | 0.07 | 0.05 | lasso | 5 | 0.03 | 0.0012 | -5.6 | 5.5 | 3.3e-08 | -0.97 | 0.02 | 0.93 | TRUE |
2 | GTEx | Thyroid | C20orf112 | 0.05 | 0.00 | lasso | 5 | 0.00 | 0.1420 | -5.6 | 5.2 | 2.3e-07 | -0.87 | 0.05 | 0.70 | FALSE |
3 | GTEx | Vagina | RSL24D1P6 | 0.44 | -0.01 | lasso | 13 | 0.00 | 0.2500 | -3.6 | 5.2 | 2.1e-07 | -0.68 | 0.03 | 0.57 | FALSE |
4 | METSIM | Adipose | KIF3B | 0.03 | 0.02 | bslmm | 357 | 0.01 | 0.0064 | -5.4 | -5.2 | 2.5e-07 | 0.70 | 0.02 | 0.94 | FALSE |