Best TWAS P=1.12e-10 · Best GWAS P=1.42e-08 conditioned to 0.768
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 7 | The Cancer Genome Atlas | Stomach Adenocarcinoma | GDF5 | 0.09 | 0.04 | enet | 13 | 0.05 | 2.4e-04 | 5.7 | 6.5 | 1.1e-10 | 0.85 | 0.00 | 0.99 | TRUE |
| 1 | GTEx | Artery Tibial | TP53INP2 | 0.09 | 0.08 | lasso | 1 | 0.07 | 5.6e-06 | 5.6 | 5.6 | 1.9e-08 | 0.06 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Artery Tibial | GSS | 0.06 | 0.02 | enet | 25 | 0.04 | 7.7e-04 | 5.6 | 5.9 | 4.6e-09 | 0.35 | 0.05 | 0.83 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GDF5 | 0.05 | 0.05 | lasso | 5 | 0.04 | 7.2e-05 | 5.7 | 5.5 | 3.9e-08 | 0.95 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GGT7 | 0.02 | 0.02 | lasso | 3 | 0.02 | 2.2e-04 | 5.6 | -5.4 | 8.7e-08 | -0.09 | 0.00 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | UQCC | 0.07 | 0.08 | blup | 67 | 0.07 | 1.1e-08 | 4.2 | -5.2 | 2.2e-07 | -0.82 | 0.05 | 0.94 | FALSE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | UQCC | 0.15 | 0.02 | blup | 67 | 0.04 | 2.0e-02 | 2.8 | -5.2 | 2.3e-07 | -0.74 | 0.02 | 0.62 | FALSE |