[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure :

chr20:24,485,525-26,307,797

Best TWAS P=2.18e-08 · Best GWAS P=3.22e-08 conditioned to 0.0802

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CTD-2514C3.1 0.06 0.02 enet 5 0.04 6.1e-04 -3.5 5.2 1.6e-07 -0.73 0.02 0.96 FALSE
2 GTEx Brain Caudate basal ganglia ABHD12 0.09 0.05 enet 13 0.04 2.9e-02 -5.3 -5.5 3.2e-08 0.95 0.06 0.82 FALSE
3 GTEx Brain Cerebellar Hemisphere ENTPD6 0.22 0.26 lasso 3 0.17 3.8e-05 -5.0 5.2 2.5e-07 -0.82 0.12 0.86 FALSE
4 GTEx Cells Transformed fibroblasts ABHD12 0.24 0.33 lasso 4 0.35 6.3e-27 -5.3 -5.4 8.1e-08 0.90 0.07 0.93 FALSE
5 GTEx Cells Transformed fibroblasts GINS1 0.04 0.01 lasso 3 0.01 5.2e-02 -4.3 -5.3 9.8e-08 0.73 0.13 0.78 FALSE
6 GTEx Colon Sigmoid ABHD12 0.17 0.17 lasso 15 0.17 1.0e-06 -5.3 -5.4 6.0e-08 0.99 0.05 0.94 FALSE
7 GTEx Heart Atrial Appendage ABHD12 0.07 0.06 enet 16 0.06 1.0e-03 -5.2 -5.2 2.2e-07 0.89 0.09 0.89 FALSE
8 GTEx Heart Left Ventricle ABHD12 0.15 0.14 lasso 10 0.12 4.0e-07 -5.1 -5.2 2.0e-07 0.87 0.11 0.89 FALSE
9 GTEx Liver ABHD12 0.20 0.20 lasso 19 0.15 7.3e-05 -5.2 -5.5 3.9e-08 0.87 0.10 0.90 FALSE
10 GTEx Muscle Skeletal ENTPD6 0.04 0.02 lasso 4 0.01 1.5e-02 -4.9 5.2 2.4e-07 -0.87 0.08 0.87 FALSE
11 GTEx Nerve Tibial ABHD12 0.24 0.44 lasso 11 0.44 5.1e-34 -5.2 5.2 2.0e-07 -0.86 0.12 0.88 FALSE
12 GTEx Ovary ABHD12 0.23 0.04 lasso 8 0.05 1.9e-02 -5.1 -5.6 2.2e-08 0.80 0.08 0.63 TRUE
13 GTEx Spleen PYGB 0.15 0.09 lasso 6 0.04 2.6e-02 -5.2 -5.5 3.7e-08 0.84 0.10 0.78 FALSE
14 GTEx Thyroid ABHD12 0.05 0.04 lasso 5 0.03 3.9e-03 -4.9 5.3 1.4e-07 -0.88 0.10 0.86 FALSE
15 GTEx Thyroid NINL 0.13 0.18 enet 17 0.20 6.2e-15 4.0 5.2 2.1e-07 -0.83 0.31 0.69 FALSE
16 GTEx Thyroid VN1R108P 0.05 0.01 lasso 2 0.02 1.8e-02 -4.3 -5.3 1.1e-07 0.77 0.10 0.71 FALSE
17 The Cancer Genome Atlas Bladder Urothelial Carcinoma ABHD12 0.04 0.00 blup 77 0.02 6.6e-03 -5.1 -5.3 1.5e-07 0.89 0.04 0.56 FALSE
18 The Cancer Genome Atlas Glioblastoma Multiforme ABHD12 0.14 0.10 lasso 5 0.13 1.1e-04 -5.3 -5.5 4.2e-08 0.98 0.05 0.91 FALSE
19 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ABHD12 0.04 0.03 blup 77 0.04 4.0e-05 -5.1 -5.3 9.6e-08 0.89 0.06 0.94 FALSE
20 The Cancer Genome Atlas Brain Lower Grade Glioma ABHD12 0.04 0.06 blup 77 0.06 2.2e-07 -5.1 -5.2 2.1e-07 0.92 0.06 0.94 FALSE
21 The Cancer Genome Atlas Prostate Adenocarcinoma ABHD12 0.03 0.02 lasso 4 0.03 5.8e-04 4.9 -5.2 1.7e-07 0.96 0.04 0.84 FALSE
22 The Cancer Genome Atlas Testicular Germ Cell Tumors NINL 0.11 0.03 blup 81 0.07 2.1e-03 5.2 5.5 4.9e-08 -0.89 0.03 0.72 FALSE