[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr20:24,485,525-26,307,797

Best TWAS P=2.18e-08 · Best GWAS P=3.22e-08 conditioned to 0.0802

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	GTEx	Ovary	ABHD12	0.23	0.04	lasso	8	0.05	1.9e-02	-5.1	-5.6	2.2e-08	0.80	0.08	0.63	TRUE
2	GTEx	Brain Caudate basal ganglia	ABHD12	0.09	0.05	enet	13	0.04	2.9e-02	-5.3	-5.5	3.2e-08	0.95	0.06	0.82	FALSE
13	GTEx	Spleen	PYGB	0.15	0.09	lasso	6	0.04	2.6e-02	-5.2	-5.5	3.7e-08	0.84	0.10	0.78	FALSE
9	GTEx	Liver	ABHD12	0.20	0.20	lasso	19	0.15	7.3e-05	-5.2	-5.5	3.9e-08	0.87	0.10	0.90	FALSE
18	The Cancer Genome Atlas	Glioblastoma Multiforme	ABHD12	0.14	0.10	lasso	5	0.13	1.1e-04	-5.3	-5.5	4.2e-08	0.98	0.05	0.91	FALSE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	NINL	0.11	0.03	blup	81	0.07	2.1e-03	5.2	5.5	4.9e-08	-0.89	0.03	0.72	FALSE
6	GTEx	Colon Sigmoid	ABHD12	0.17	0.17	lasso	15	0.17	1.0e-06	-5.3	-5.4	6.0e-08	0.99	0.05	0.94	FALSE
4	GTEx	Cells Transformed fibroblasts	ABHD12	0.24	0.33	lasso	4	0.35	6.3e-27	-5.3	-5.4	8.1e-08	0.90	0.07	0.93	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ABHD12	0.04	0.03	blup	77	0.04	4.0e-05	-5.1	-5.3	9.6e-08	0.89	0.06	0.94	FALSE
5	GTEx	Cells Transformed fibroblasts	GINS1	0.04	0.01	lasso	3	0.01	5.2e-02	-4.3	-5.3	9.8e-08	0.73	0.13	0.78	FALSE
16	GTEx	Thyroid	VN1R108P	0.05	0.01	lasso	2	0.02	1.8e-02	-4.3	-5.3	1.1e-07	0.77	0.10	0.71	FALSE
14	GTEx	Thyroid	ABHD12	0.05	0.04	lasso	5	0.03	3.9e-03	-4.9	5.3	1.4e-07	-0.88	0.10	0.86	FALSE
17	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ABHD12	0.04	0.00	blup	77	0.02	6.6e-03	-5.1	-5.3	1.5e-07	0.89	0.04	0.56	FALSE
1	GTEx	Adipose Subcutaneous	CTD-2514C3.1	0.06	0.02	enet	5	0.04	6.1e-04	-3.5	5.2	1.6e-07	-0.73	0.02	0.96	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	ABHD12	0.03	0.02	lasso	4	0.03	5.8e-04	4.9	-5.2	1.7e-07	0.96	0.04	0.84	FALSE
8	GTEx	Heart Left Ventricle	ABHD12	0.15	0.14	lasso	10	0.12	4.0e-07	-5.1	-5.2	2.0e-07	0.87	0.11	0.89	FALSE
11	GTEx	Nerve Tibial	ABHD12	0.24	0.44	lasso	11	0.44	5.1e-34	-5.2	5.2	2.0e-07	-0.86	0.12	0.88	FALSE
15	GTEx	Thyroid	NINL	0.13	0.18	enet	17	0.20	6.2e-15	4.0	5.2	2.1e-07	-0.83	0.31	0.69	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	ABHD12	0.04	0.06	blup	77	0.06	2.2e-07	-5.1	-5.2	2.1e-07	0.92	0.06	0.94	FALSE
7	GTEx	Heart Atrial Appendage	ABHD12	0.07	0.06	enet	16	0.06	1.0e-03	-5.2	-5.2	2.2e-07	0.89	0.09	0.89	FALSE
10	GTEx	Muscle Skeletal	ENTPD6	0.04	0.02	lasso	4	0.01	1.5e-02	-4.9	5.2	2.4e-07	-0.87	0.08	0.87	FALSE
3	GTEx	Brain Cerebellar Hemisphere	ENTPD6	0.22	0.26	lasso	3	0.17	3.8e-05	-5.0	5.2	2.5e-07	-0.82	0.12	0.86	FALSE