TWAS hub - UQCC

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0680	0.0280	9.3e-06	0.041	0.040	0.044	0.039	0.048	8.8e-06	1.1e-05	4.2e-06	1.5e-05	1.4e-06
2	NTR	Blood	0.0125	0.0080	1.2e-02	0.006	0.002	0.004	0.003	0.004	2.7e-03	4.6e-02	1.6e-02	2.1e-02	1.9e-02
3	YFS	Blood	0.2053	0.0406	0.0e+00	0.189	0.195	0.196	0.197	0.202	1.7e-59	1.2e-61	6.7e-62	2.5e-62	6.4e-64
4	TCGA	Bladder Urothelial Carcinoma	0.0270	0.0180	6.5e-03	0.037	0.026	0.023	NA	0.023	3.8e-04	2.6e-03	4.1e-03	NA	4.3e-03
5	TCGA	Breast Invasive Carcinoma	0.0802	0.0322	0.0e+00	0.109	0.115	0.114	NA	0.113	1.8e-21	1.1e-22	1.8e-22	NA	2.5e-22
6	TCGA	Glioblastoma Multiforme	0.1460	0.0850	1.9e-03	0.017	0.042	-0.009	NA	0.017	9.9e-02	2.0e-02	8.3e-01	NA	9.7e-02
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.0520	0.0245	6.0e-07	0.055	0.059	0.042	NA	0.058	7.4e-07	3.6e-07	1.6e-05	NA	4.5e-07
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0871	0.0372	2.4e-09	0.105	0.095	0.092	NA	0.095	7.6e-12	7.2e-11	1.6e-10	NA	7.5e-11
9	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0840	0.0490	5.5e-04	0.014	0.007	0.008	NA	0.009	4.8e-02	1.2e-01	1.0e-01	NA	9.0e-02
10	TCGA	Brain Lower Grade Glioma	0.0400	0.0170	1.8e-06	0.063	0.048	0.049	NA	0.050	1.2e-07	3.2e-06	2.5e-06	NA	2.3e-06
11	TCGA	Lung Adenocarcinoma	0.0956	0.0528	6.8e-08	0.073	0.061	0.070	NA	0.069	6.2e-09	1.1e-07	1.5e-08	NA	1.6e-08
12	TCGA	Lung Squamous Cell Carcinoma	0.0701	0.0318	5.0e-09	0.079	0.073	0.064	NA	0.069	2.9e-09	1.1e-08	8.3e-08	NA	2.9e-08
13	TCGA	Pancreatic Adenocarcinoma	0.1190	0.0620	7.1e-04	0.029	0.087	0.067	NA	0.053	2.2e-02	1.7e-04	9.0e-04	NA	3.0e-03
14	TCGA	Pheochromocytoma and Paraganglioma	0.2220	0.0870	1.7e-08	0.214	0.174	0.150	NA	0.175	5.9e-09	2.0e-07	1.4e-06	NA	1.9e-07
15	TCGA	Prostate Adenocarcinoma	0.0733	0.0307	8.5e-11	0.105	0.105	0.091	NA	0.111	4.1e-11	4.6e-11	1.0e-09	NA	1.3e-11
16	TCGA	Soft Tissue Sarcoma	0.0650	0.0330	8.9e-05	0.062	0.071	0.058	NA	0.068	1.4e-04	5.2e-05	2.4e-04	NA	7.4e-05
17	TCGA	Stomach Adenocarcinoma	0.0740	0.0390	1.8e-04	0.060	0.061	0.013	NA	0.062	4.0e-05	3.5e-05	3.7e-02	NA	2.8e-05
18	TCGA	Thyroid Carcinoma	0.1490	0.0530	0.0e+00	0.211	0.215	0.133	NA	0.214	3.2e-20	1.2e-20	7.0e-13	NA	1.4e-20
19	TCGA	Uterine Corpus Endometrial Carcinoma	0.1330	0.0650	1.7e-03	0.147	0.093	0.063	NA	0.106	6.8e-05	1.5e-03	7.8e-03	NA	7.1e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Sitting height	118.7	842.4	967.2	-31.1	-30.5	-29.4	-31.1	-30.1	-26.9	-29.0	-28.8	-24.7	-29.7	-29.5	-27.8	-27.9	-29.8	-30.6	-30.2	-28.8	-30.5	-23.8
Standing height	94.5	937.7	1076.0	-32.1	-32.3	-31.6	-32.8	-31.4	-28.3	-30.6	-30.7	-25.3	-31.8	-31.6	-30.3	-28.6	-31.1	-32.3	-31.9	-30.8	-31.8	-25.2
Height	92.7	1787.2	2025.0	-44.4	-44.5	-43.7	-45.0	-43.5	-38.9	-42.3	-42.6	-35.7	-43.7	-43.6	-41.6	-39.6	-42.8	-44.6	-43.9	-42.4	-43.9	-34.7
Comparative height size at age 10	87.4	481.3	538.2	-23.2	-22.6	-22.2	-23.2	-22.8	-19.3	-21.9	-22.4	-19.4	-22.7	-22.4	-20.8	-20.9	-22.1	-22.9	-22.5	-22.7	-23.0	-19.1
Trunk predicted mass	83.6	477.7	538.2	-23.1	-23.2	-22.1	-23.2	-22.6	-19.8	-21.7	-22.2	-18.8	-22.4	-22.1	-21.3	-21.0	-23.0	-23.0	-22.5	-21.7	-22.6	-18.1
Trunk fat-free mass	83.5	479.5	538.2	-23.1	-23.2	-22.1	-23.2	-22.7	-19.8	-21.8	-22.2	-18.9	-22.5	-22.1	-21.3	-21.1	-23.0	-23.1	-22.5	-21.7	-22.7	-18.2
Whole body fat-free mass	79.6	455.0	510.8	-22.5	-22.6	-21.4	-22.6	-22.1	-19.3	-21.2	-21.6	-18.7	-21.9	-21.4	-20.6	-20.5	-22.4	-22.5	-21.9	-21.2	-22.2	-17.9
Whole body water mass	77.6	442.5	497.3	-22.3	-22.3	-21.1	-22.3	-21.8	-19.0	-20.9	-21.3	-18.4	-21.6	-21.1	-20.3	-20.2	-22.2	-22.1	-21.6	-20.9	-21.9	-17.6
Leg predicted mass (right)	73.7	393.4	441.0	-20.9	-20.8	-19.8	-21.0	-20.6	-17.7	-19.8	-20.0	-17.7	-20.4	-19.8	-18.9	-19.0	-20.9	-20.9	-20.5	-19.8	-20.7	-17.0
Leg fat-free mass (right)	73.6	393.0	441.0	-20.9	-20.9	-19.8	-21.0	-20.6	-17.7	-19.8	-20.0	-17.8	-20.3	-19.8	-18.9	-18.9	-20.8	-20.9	-20.4	-19.8	-20.7	-17.0
Leg predicted mass (left)	70.3	372.3	420.2	-20.5	-20.2	-19.3	-20.4	-20.0	-17.3	-19.3	-19.4	-17.4	-19.8	-19.1	-18.2	-18.5	-20.2	-20.3	-19.9	-19.3	-20.3	-16.6
Basal metabolic rate	70.2	388.7	436.8	-20.9	-20.8	-19.8	-20.8	-20.5	-17.6	-19.6	-20.0	-17.5	-20.2	-19.7	-18.8	-19.1	-20.8	-20.7	-20.2	-19.6	-20.6	-16.7
Leg fat-free mass (left)	70.1	371.3	416.2	-20.4	-20.2	-19.3	-20.4	-20.0	-17.2	-19.2	-19.5	-17.4	-19.7	-19.1	-18.2	-18.5	-20.2	-20.3	-19.8	-19.3	-20.2	-16.6
Arm predicted mass (left)	66.3	337.2	380.2	-19.5	-19.5	-18.3	-19.3	-19.0	-16.4	-18.3	-18.7	-16.3	-18.7	-18.5	-17.8	-17.7	-19.5	-19.3	-18.8	-18.1	-19.1	-15.4
Arm predicted mass (right)	66.1	337.9	385.8	-19.5	-19.6	-18.4	-19.3	-19.0	-16.6	-18.1	-18.8	-15.8	-18.8	-18.6	-18.0	-17.9	-19.6	-19.3	-18.7	-18.3	-18.9	-15.2
Arm fat-free mass (right)	65.9	337.7	388.1	-19.5	-19.7	-18.5	-19.3	-19.1	-16.6	-18.1	-18.7	-15.8	-18.8	-18.6	-18.0	-17.9	-19.6	-19.3	-18.7	-18.2	-18.9	-15.1
Arm fat-free mass (left)	65.4	331.9	375.9	-19.3	-19.4	-18.3	-19.2	-18.9	-16.4	-18.1	-18.5	-15.9	-18.6	-18.4	-17.7	-17.6	-19.2	-19.2	-18.7	-18.0	-18.9	-15.1
Hand grip strength (right)	48.9	133.0	161.3	-12.1	-12.0	-12.1	-12.7	-11.7	-11.2	-11.6	-11.1	-9.9	-11.8	-11.4	-10.9	-10.4	-11.6	-12.2	-12.2	-11.5	-12.4	-9.8
Forced expiratory volume in 1-second (FEV1), predicted	44.2	91.7	111.1	-10.3	-10.1	-9.1	-10.1	-9.8	-8.7	-10.0	-9.3	-9.3	-9.6	-9.8	-9.4	-8.4	-9.9	-9.9	-10.3	-9.2	-10.5	-7.9
Hand grip strength (left)	39.0	102.7	123.2	-10.6	-10.5	-10.8	-11.1	-10.3	-9.9	-10.1	-9.7	-8.7	-10.4	-9.9	-9.5	-9.1	-10.3	-10.8	-10.8	-10.0	-10.9	-8.7
Weight	36.7	180.6	209.1	-14.5	-14.1	-13.4	-14.1	-14.2	-11.5	-13.3	-13.8	-12.4	-13.7	-13.3	-12.3	-13.5	-14.2	-14.1	-13.6	-13.4	-14.1	-11.6
Knee pain experienced in last month	35.3	54.9	65.3	7.6	8.1	7.2	8.0	7.7	6.2	7.4	7.6	5.7	7.8	7.6	6.9	7.6	7.5	7.8	7.7	7.7	7.7	6.5
Tanning	34.4	419.4	1267.4	-21.1	-26.6	-13.9	-21.8	-19.6	-18.2	-18.1	-17.0	-16.7	-18.5	-18.6	-22.6	-20.1	-35.6	-20.2	-20.8	-16.1	-18.2	-15.3
Lung FVC	27.4	139.7	163.8	12.8	12.3	12.0	12.5	12.5	10.8	11.6	11.9	9.3	12.2	12.4	11.3	12.1	12.1	12.6	12.1	12.0	11.9	9.4
Peak expiratory flow (PEF)	23.8	55.2	65.3	-7.6	-7.8	-8.0	-8.1	-7.6	-7.1	-7.4	-7.3	-6.2	-7.8	-7.6	-7.6	-6.7	-7.5	-7.8	-7.7	-7.4	-7.7	-5.9
Hip circumference	22.4	96.5	116.6	-10.8	-10.3	-9.5	-10.1	-10.5	-7.9	-9.6	-10.4	-9.4	-9.9	-9.5	-8.5	-10.3	-10.4	-10.2	-9.7	-10.1	-10.3	-8.7
Impedance of leg (left)	17.6	85.7	102.2	9.8	9.7	9.0	9.7	9.7	8.1	9.2	9.3	8.8	9.5	8.8	8.4	9.1	10.1	9.8	9.5	9.3	9.7	8.1
Impedance of leg (right)	17.3	83.7	101.3	9.4	9.8	8.7	9.5	9.6	7.8	9.3	9.2	8.7	9.4	8.9	8.6	8.9	10.1	9.7	9.5	9.0	9.5	7.9
Hair Pigment	15.3	435.1	1407.2	22.3	27.4	13.9	21.9	19.9	18.6	17.3	17.4	17.6	18.4	17.7	22.2	21.5	37.5	20.3	20.3	16.9	18.3	15.4
Waist Hip Ratio (WHR)	13.3	59.7	80.0	8.9	7.9	7.7	8.2	8.3	7.0	7.4	8.1	7.1	7.7	7.3	6.4	8.1	7.9	8.2	7.5	7.9	8.2	6.7
Relative age voice broke	12.5	19.2	24.6	4.9	4.3	3.6	4.5	4.5	3.2	4.6	4.3	4.9	4.2	4.3	3.7	4.2	5.0	4.4	4.5	4.4	4.8	4.4
Trunk fat mass	9.9	42.5	51.7	-7.2	-6.5	-6.4	-6.7	-7.1	-5.3	-6.4	-6.8	-6.6	-6.6	-6.3	-5.5	-6.9	-6.8	-6.8	-6.4	-6.5	-6.9	-5.9
Leg fat percentage (right)	9.2	33.2	42.2	5.4	6.2	6.1	6.5	5.5	6.0	6.0	5.3	3.9	6.2	6.3	6.5	4.3	5.5	6.2	6.5	5.8	5.8	4.5
Medication: Lansoprazole	8.5	9.7	12.2	3.4	3.5	2.9	3.4	2.9	3.1	3.1	3.2	2.8	3.2	3.1	3.4	2.4	3.2	3.2	3.2	3.1	3.2	2.7
Leg fat percentage (left)	8.5	30.8	39.4	5.3	5.9	6.0	6.3	5.3	6.0	5.7	5.0	3.7	6.0	5.9	6.1	4.2	5.3	6.0	6.2	5.7	5.6	4.3
Prostate Cancer	8.2	11.6	14.3	3.7	3.2	3.1	3.5	3.6	2.6	3.7	3.6	3.6	3.4	3.2	2.7	3.5	3.4	3.6	3.5	3.3	3.8	3.4
Qualifications: A levels/AS levels or equivalent	7.9	17.6	23.0	-4.8	-4.4	-4.3	-4.6	-4.4	-3.7	-4.0	-4.2	-3.7	-4.1	-3.9	-3.4	-4.1	-4.3	-4.3	-4.2	-4.5	-4.7	-3.8
Forced vital capacity (FVC), Best measure	7.9	29.0	36.0	-5.3	-6.0	-5.6	-5.9	-5.1	-5.6	-5.4	-5.3	-4.7	-5.5	-5.2	-5.9	-4.3	-5.6	-5.6	-5.8	-5.1	-5.8	-4.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	7.8	16.6	22.9	4.6	4.3	3.4	4.2	4.5	2.6	4.1	3.9	3.6	4.1	4.2	3.1	4.4	4.6	4.1	4.1	4.8	4.0	4.1
Impedance of whole body	7.6	38.6	56.8	6.6	6.9	5.7	6.4	6.5	5.2	6.0	6.4	6.1	6.1	5.7	5.6	6.5	7.5	6.5	6.2	5.9	6.4	5.3
Qualifications: O levels/GCSEs or equivalent	7.2	11.4	15.3	-3.3	-3.4	-3.0	-3.2	-3.8	-1.5	-3.5	-3.8	-3.6	-3.4	-3.3	-2.4	-3.7	-3.7	-3.3	-3.3	-3.8	-3.6	-3.9
Supplements: Zinc	6.9	7.5	11.5	-2.7	-2.8	-1.9	-2.9	-3.0	-1.5	-3.2	-2.5	-3.0	-2.6	-2.7	-2.2	-2.7	-3.4	-2.7	-3.1	-2.5	-3.0	-3.1
Diabetes (mother)	6.4	8.2	13.6	-3.0	-2.7	-2.4	-2.8	-3.1	-1.4	-3.2	-3.0	-3.5	-2.8	-2.3	-1.8	-3.1	-3.0	-2.9	-2.9	-2.6	-3.2	-3.7
Forced vital capacity (FVC)	6.4	24.8	29.9	-4.8	-5.4	-5.0	-5.4	-4.7	-4.6	-5.1	-5.0	-4.9	-5.0	-4.7	-5.1	-4.0	-5.3	-5.1	-5.3	-4.8	-5.5	-4.6
Whole body fat mass	6.4	26.9	32.7	-5.7	-5.2	-5.0	-5.2	-5.7	-4.1	-5.1	-5.5	-5.5	-5.2	-4.9	-4.4	-5.6	-5.6	-5.4	-5.0	-5.0	-5.5	-4.6
Qualifications: None of the above	6.1	13.0	16.1	3.8	3.7	3.9	4.0	3.9	2.8	3.5	3.5	2.9	3.7	3.5	2.6	4.0	3.5	3.8	3.7	3.9	3.9	3.4
Systolic Blood Pressure	5.9	29.5	35.6	-5.6	-5.4	-4.8	-5.9	-5.5	-3.9	-5.9	-5.4	-5.5	-5.5	-5.4	-4.7	-5.1	-5.5	-5.6	-5.9	-5.6	-6.0	-5.7
Hair/balding pattern: Pattern 3	5.6	8.4	14.1	-3.2	-3.0	-3.0	-3.2	-3.4	-2.0	-2.8	-2.9	-1.8	-3.0	-2.8	-2.0	-3.8	-3.1	-3.2	-2.9	-2.6	-2.9	-2.5
Forced expiratory volume in 1-second (FEV1), Best measure	5.6	17.8	26.8	-4.2	-4.7	-4.7	-4.6	-3.7	-5.2	-4.0	-4.0	-3.4	-4.3	-4.1	-5.2	-2.9	-4.3	-4.4	-4.5	-3.8	-4.5	-2.8
Commuting to job workplace: Cycle	5.6	6.7	11.6	-2.8	-2.6	-2.9	-2.9	-2.1	-3.4	-2.4	-2.3	-2.0	-2.8	-2.5	-3.2	-1.3	-2.4	-2.7	-2.7	-3.0	-2.6	-1.9
Relative age of first facial hair	5.5	11.4	17.1	4.1	3.3	2.8	3.5	3.6	2.3	3.5	3.4	3.6	3.1	3.3	2.4	3.8	3.7	3.4	3.4	3.4	3.7	3.2
Ulcerative Colitis	5.2	7.6	11.0	-2.8	-2.8	-2.9	-3.1	-2.2	-3.2	-3.3	-2.2	-2.8	-2.8	-2.9	-3.3	-1.3	-2.5	-2.8	-3.3	-2.1	-3.1	-1.9
Arm fat mass (right)	5.1	20.8	29.3	-5.1	-4.5	-4.2	-4.5	-5.0	-3.4	-4.6	-4.8	-5.4	-4.4	-4.1	-3.5	-5.0	-4.9	-4.7	-4.4	-4.4	-5.0	-4.3
Osteoarthritis (self-reported)	5.1	6.7	9.1	2.6	2.8	2.3	3.0	3.0	2.0	2.6	2.3	1.6	2.8	2.6	1.7	2.9	2.6	2.9	2.9	2.5	2.9	2.5
Forced expiratory volume in 1-second (FEV1)	5.0	16.8	20.5	-4.2	-4.4	-4.4	-4.5	-3.7	-4.4	-4.0	-4.1	-3.8	-4.2	-3.8	-4.5	-3.1	-4.3	-4.2	-4.3	-4.0	-4.5	-3.4
Mouth/teeth dental problems: Mouth ulcers	5.0	8.0	9.8	2.8	2.8	3.0	3.0	3.1	2.7	2.9	2.7	2.4	3.0	2.8	2.5	2.5	2.9	3.1	3.0	2.7	2.9	2.5
Arm fat mass (left)	5.0	20.7	26.4	-5.1	-4.5	-4.3	-4.5	-5.0	-3.5	-4.5	-4.8	-5.1	-4.5	-4.2	-3.7	-5.0	-4.9	-4.7	-4.4	-4.4	-4.9	-4.1
Hair/balding pattern: Pattern 2	4.9	6.3	9.4	2.6	2.9	2.2	2.8	2.6	1.9	2.5	2.1	1.9	2.7	2.7	2.2	2.2	3.1	2.5	2.7	2.7	2.5	2.2
Birth weight	4.9	10.6	14.1	-3.4	-3.3	-3.8	-3.7	-3.3	-3.4	-3.1	-2.9	-1.9	-3.5	-3.4	-3.2	-3.1	-3.1	-3.5	-3.5	-3.5	-3.2	-2.5
Qualifications: College or University degree	4.9	15.3	21.3	-4.0	-4.3	-4.6	-4.5	-4.1	-4.0	-3.8	-3.5	-2.3	-4.1	-4.0	-3.8	-3.6	-4.0	-4.3	-4.2	-3.7	-4.0	-2.8
Average weekly red wine intake	4.9	7.3	8.7	-3.0	-2.7	-2.9	-2.7	-2.8	-2.4	-2.6	-2.8	-2.9	-2.6	-2.9	-2.5	-2.4	-2.6	-2.7	-2.6	-2.9	-2.9	-1.9
Chronic bronchitis/emphysema (mother)	4.7	5.5	9.1	2.2	2.4	2.1	2.6	2.8	1.0	2.5	2.4	1.8	2.5	2.2	1.1	3.0	2.4	2.5	2.5	2.2	2.5	2.9
LDL Cholesterol	4.6	7.3	10.6	2.5	2.7	2.6	2.6	2.9	1.6	2.9	3.3	2.3	2.8	2.8	2.9	2.8	3.2	2.8	2.7	2.5	2.6	2.7
Lung cancer (father)	4.6	5.4	7.1	-2.0	-2.6	-2.5	-2.5	-2.7	-1.8	-2.5	-2.1	-2.1	-2.5	-2.3	-1.9	-2.1	-2.5	-2.5	-2.7	-2.0	-2.6	-2.2
Maternal smoking around birth	4.4	6.4	10.9	2.3	3.0	2.2	2.5	3.0	1.1	2.5	2.9	2.1	2.5	2.7	1.6	3.3	2.8	2.6	2.4	2.3	2.5	2.8
Diabetes (father)	4.0	5.0	7.7	-2.7	-2.6	-1.9	-2.2	-2.4	-1.7	-1.8	-2.1	-2.0	-2.2	-2.2	-1.7	-2.7	-2.7	-2.2	-2.1	-2.8	-2.0	-2.0
Townsend deprivation index at recruitment	3.8	5.3	7.5	2.7	2.4	2.1	2.6	2.4	1.9	2.4	2.0	2.1	2.1	2.1	1.6	2.5	2.4	2.4	2.5	2.1	2.7	2.2
Alcohol intake versus 10 years previously	3.6	5.4	8.1	-2.1	-2.4	-2.0	-2.2	-2.2	-1.7	-2.8	-2.3	-2.5	-2.4	-2.5	-2.8	-1.6	-2.3	-2.3	-2.7	-2.2	-2.4	-2.3
Pulse rate	3.6	6.0	13.8	2.8	2.3	2.9	2.5	2.8	1.8	2.0	2.9	1.6	2.5	2.1	1.5	3.7	2.3	2.6	2.1	2.7	2.4	2.1
Number of full sisters	3.6	4.4	6.8	1.6	2.5	2.3	2.3	2.2	2.4	2.1	1.8	0.9	2.4	2.4	2.6	1.7	2.1	2.3	2.4	1.6	2.0	1.3
Medication: Gliclazide	3.6	4.1	6.9	-2.5	-2.1	-1.8	-2.2	-1.7	-2.0	-1.9	-1.9	-2.6	-1.9	-1.5	-1.4	-1.4	-2.2	-2.0	-2.0	-2.3	-2.5	-2.1
Average weekly beer plus cider intake	3.6	5.3	7.1	2.5	2.4	2.2	2.2	2.5	1.8	2.4	2.5	2.0	2.3	2.7	2.3	2.2	2.2	2.4	2.3	2.6	2.2	1.8
Multivitamins +/- minerals	3.4	4.3	6.8	-2.2	-2.1	-1.9	-2.1	-2.0	-2.0	-2.6	-1.7	-2.1	-2.0	-2.2	-2.3	-1.4	-2.1	-2.2	-2.6	-1.4	-2.4	-1.8
Deep venous thrombosis (DVT) (self-reported)	3.4	4.3	11.8	-2.2	-2.1	-2.1	-2.5	-1.6	-3.4	-2.1	-1.1	-0.9	-1.9	-2.2	-3.0	-0.8	-2.0	-2.2	-2.7	-1.2	-2.4	-0.6
Systolic blood pressure, automated reading	3.3	9.6	12.2	-3.4	-2.9	-2.9	-3.4	-3.1	-2.4	-3.5	-3.0	-3.2	-3.0	-3.1	-2.7	-3.0	-3.1	-3.2	-3.5	-2.8	-3.5	-2.9
Chronotype (morning person)	3.2	7.3	11.1	-2.3	-2.8	-2.9	-2.8	-2.7	-2.1	-3.3	-2.3	-2.6	-3.0	-3.3	-3.0	-2.0	-2.3	-2.8	-3.2	-2.2	-2.8	-2.4
High blood pressure (mother)	3.2	4.6	7.6	-2.4	-2.6	-2.0	-2.2	-2.4	-1.4	-1.7	-2.2	-1.6	-2.1	-2.1	-1.8	-2.8	-2.6	-2.2	-1.9	-2.3	-1.9	-1.7
Myopia	3.1	4.5	7.7	-2.2	-2.1	-2.4	-2.2	-2.2	-1.6	-2.0	-2.3	-0.8	-2.3	-2.5	-2.2	-2.8	-2.0	-2.2	-2.2	-2.2	-1.8	-1.4
Bipolar Disorder (2011)	3.0	2.9	4.6	-1.6	-2.1	-1.6	-1.7	-1.9	-1.2	-1.9	-1.5	-1.3	-1.7	-1.7	-1.5	-1.7	-1.9	-1.9	-2.0	-1.3	-1.8	-1.7
Coronary Artery Disease (CAD)	3.0	3.6	6.8	-2.6	-1.8	-2.1	-1.7	-1.9	-2.1	-1.6	-1.6	-2.3	-1.8	-1.7	-1.5	-1.8	-2.1	-2.0	-1.7	-2.1	-2.0	-1.2
Past tobacco smoking	3.0	5.5	8.6	-2.8	-2.2	-2.2	-2.7	-2.5	-1.8	-2.5	-2.0	-2.4	-2.1	-1.8	-1.6	-2.4	-2.9	-2.5	-2.6	-2.0	-2.7	-2.5
Sensitivity / hurt feelings	2.9	4.9	7.4	2.1	2.6	2.1	2.7	2.3	1.7	2.0	2.0	1.0	2.4	2.0	1.7	2.7	2.7	2.4	2.3	2.3	2.0	2.2
Blood clot in the leg (DVT)	2.9	3.7	9.5	-2.1	-2.0	-1.8	-2.3	-1.5	-3.1	-2.1	-1.0	-1.0	-1.7	-2.1	-2.7	-0.7	-1.8	-2.0	-2.6	-1.1	-2.3	-0.6
Smoking status: Previous	2.9	4.4	6.5	2.4	1.9	1.9	2.4	2.2	1.6	2.3	1.7	2.5	1.9	1.7	1.5	1.9	2.6	2.2	2.3	1.9	2.4	2.5
Commuting to job workplace: Walk	2.9	3.1	4.9	-1.7	-1.8	-1.9	-2.1	-1.5	-1.8	-1.8	-1.8	-0.5	-1.9	-2.2	-2.1	-1.6	-1.5	-1.9	-1.9	-1.9	-1.5	-0.9
Lung FEV1/FVC ratio	2.8	14.0	31.2	-4.2	-3.9	-5.0	-4.2	-3.2	-5.6	-3.0	-3.2	-2.0	-3.8	-3.7	-4.7	-2.6	-3.5	-4.0	-3.8	-3.3	-3.7	-1.4
Waist circumference	2.8	10.3	13.9	-3.4	-3.4	-2.9	-3.0	-3.6	-1.7	-3.2	-3.6	-3.7	-3.2	-3.0	-2.6	-3.7	-3.7	-3.2	-3.0	-3.2	-3.3	-3.1
Number of operations (self-reported)	2.8	4.2	9.2	2.1	2.2	2.4	2.3	1.8	3.0	2.0	1.6	1.7	2.1	1.8	2.3	1.3	1.9	2.2	2.2	1.8	2.0	1.3
Mouth/teeth dental problems: Bleeding gums	2.7	3.5	8.3	2.1	1.8	2.1	2.1	1.6	2.9	1.9	1.1	0.8	1.8	2.1	2.4	1.3	1.7	2.0	2.3	1.5	1.8	0.6
Age at last live birth	2.7	3.9	5.4	-1.7	-1.9	-2.1	-2.2	-1.9	-2.1	-2.0	-2.0	-1.7	-2.1	-2.0	-2.3	-1.5	-2.1	-2.2	-2.0	-1.9	-2.0	-1.5
Ever taken oral contraceptive pill	2.6	2.9	4.3	1.5	1.9	1.6	1.6	1.9	1.5	1.8	1.5	1.4	1.8	2.0	2.1	1.6	2.0	1.9	2.0	1.3	1.6	1.3
Average weekly champagne plus white wine intake	2.5	3.5	6.4	-2.0	-2.2	-2.2	-2.1	-2.1	-1.6	-1.3	-1.9	-0.7	-2.0	-1.6	-1.4	-2.5	-2.1	-2.0	-1.6	-2.1	-1.6	-1.5
Qualifications: CSEs or equivalent	2.4	3.2	5.2	2.0	2.0	2.2	1.8	1.9	1.3	1.6	2.1	0.8	1.9	2.3	1.9	2.2	1.5	1.9	1.6	1.7	1.5	0.8
Alcohol usually taken with meals	2.4	3.8	5.7	-1.8	-2.3	-1.7	-1.9	-2.1	-1.3	-1.8	-2.4	-1.7	-1.9	-2.2	-2.1	-2.2	-2.2	-2.0	-1.7	-2.2	-1.8	-1.3
Impedance of arm (left)	2.4	10.9	21.5	3.6	4.0	2.7	3.2	3.5	2.3	3.1	3.6	3.5	3.0	2.9	2.9	3.9	4.6	3.3	3.0	2.9	3.2	2.8
Pulse wave reflection index	2.4	3.0	7.0	-2.2	-1.9	-2.1	-1.8	-1.9	-1.2	-1.4	-1.8	-0.8	-1.9	-1.7	-1.1	-2.6	-1.7	-1.8	-1.4	-2.0	-1.3	-1.4
Age when periods started (menarche)	2.3	5.6	15.6	2.8	2.0	1.0	2.1	2.5	0.1	2.1	2.5	3.8	1.9	1.0	0.1	3.0	2.9	1.9	1.8	2.6	2.6	4.0
Nervous feelings	2.3	4.3	11.8	1.9	2.3	1.1	2.3	2.5	0.9	1.8	1.7	1.5	2.0	1.5	1.0	2.9	3.4	2.1	2.1	1.9	2.0	2.7
Eye problems/disorders: Glaucoma	2.3	2.7	4.3	1.5	1.5	1.8	1.6	1.9	0.9	2.1	1.7	1.6	1.9	1.8	1.3	1.7	1.0	1.8	1.9	1.2	1.9	1.7
High cholesterol (Self-reported)	2.2	3.9	8.7	2.2	2.0	2.2	2.2	1.6	2.9	1.8	1.8	1.5	2.1	2.0	2.5	0.9	1.5	2.1	1.9	2.2	1.9	0.9
Impedance of arm (right)	2.1	9.6	20.2	3.3	3.9	2.6	3.0	3.2	2.5	2.6	3.5	2.8	2.8	2.7	3.0	3.8	4.5	3.1	2.7	2.8	2.8	2.3
Diverticular disease/diverticulitis (self-reported)	2.0	2.4	3.4	1.2	1.5	1.6	1.7	1.7	1.5	1.6	1.6	0.8	1.8	1.8	1.8	1.6	1.5	1.7	1.9	1.3	1.5	0.9
Diabetes (self-reported)	2.0	3.1	5.4	-1.9	-2.0	-1.7	-1.9	-2.0	-1.3	-1.6	-1.8	-1.1	-1.8	-1.6	-1.5	-2.3	-2.2	-1.8	-1.7	-1.9	-1.6	-1.6
Mouth/teeth dental problems: Loose teeth	2.0	2.3	4.5	-1.3	-2.1	-1.6	-1.4	-1.7	-1.1	-1.4	-1.7	-1.2	-1.6	-1.5	-1.7	-1.6	-2.1	-1.6	-1.3	-1.1	-1.1	-1.3
Ulcerative Colitis (UC)	1.9	3.5	8.3	-2.0	-1.6	-2.1	-2.2	-1.3	-2.9	-2.3	-1.0	-2.1	-1.6	-1.7	-2.3	-0.3	-1.5	-1.9	-2.5	-0.9	-2.5	-1.1
Major Depression (MDD)	1.9	2.3	4.6	1.3	1.8	1.9	1.8	1.2	2.1	1.3	1.3	0.5	1.9	1.3	1.8	0.9	1.6	1.7	1.6	1.6	1.3	1.2
Fluid intelligence score	1.9	4.0	8.1	-2.1	-2.2	-2.5	-2.1	-2.3	-1.6	-1.6	-2.4	-0.7	-2.1	-2.1	-1.7	-2.9	-1.7	-2.2	-1.6	-2.0	-1.7	-1.5
Length of working week for main job	1.9	2.1	4.2	-1.8	-1.7	-1.3	-1.5	-1.7	-1.1	-1.2	-1.4	-0.6	-1.4	-1.5	-1.0	-2.0	-1.5	-1.6	-1.4	-1.6	-1.3	-1.0
Family relationship satisfaction	1.9	2.3	3.4	-1.7	-1.6	-1.4	-1.5	-1.6	-0.9	-1.5	-1.7	-1.7	-1.6	-1.5	-1.0	-1.6	-1.2	-1.4	-1.4	-1.8	-1.6	-1.7
Cholesterol lowering medication	1.9	2.8	6.0	1.7	1.8	2.0	1.8	1.3	2.1	1.3	1.6	1.4	1.9	1.6	1.8	0.5	1.5	1.7	1.4	2.4	1.4	1.4
HDL Cholesterol	1.8	3.1	6.3	2.1	1.7	1.8	1.9	1.8	1.4	1.7	1.6	1.6	1.5	1.1	1.2	2.1	2.5	1.8	1.8	1.6	1.8	1.8
Had menopause	1.8	2.3	3.7	-1.2	-1.5	-1.7	-1.5	-1.8	-1.0	-1.7	-1.5	-0.5	-1.6	-1.9	-1.8	-1.9	-1.4	-1.6	-1.7	-0.9	-1.3	-0.9
Alzheimer’s Disease (in father)	1.7	1.8	3.4	0.7	1.5	1.3	1.2	1.3	0.5	1.8	1.5	1.4	1.4	1.6	1.8	0.9	1.6	1.3	1.5	0.9	1.3	1.4
Lupus	1.7	2.6	8.7	-1.7	-1.7	-2.1	-2.0	-1.4	-3.0	-1.1	-1.1	-0.1	-1.7	-1.5	-2.1	-0.9	-1.4	-1.9	-1.6	-1.5	-1.4	-0.1
Pulse wave Arterial Stiffness index	1.7	2.0	3.6	-1.7	-1.5	-1.6	-1.4	-1.7	-0.8	-1.4	-1.5	-0.8	-1.5	-1.6	-1.1	-1.9	-1.4	-1.5	-1.3	-1.1	-1.3	-1.1
Hypothyroidism/myxoedema (self-reported)	1.7	3.4	4.7	-1.8	-2.0	-1.9	-1.7	-2.1	-1.2	-1.8	-1.9	-1.7	-2.0	-2.0	-1.8	-2.1	-2.2	-1.9	-1.7	-1.9	-1.4	-1.8
Medication for cholesterol	1.7	2.6	5.0	-1.9	-1.8	-1.8	-1.9	-1.5	-2.0	-1.2	-1.4	-1.2	-1.7	-1.4	-1.3	-1.1	-1.7	-1.7	-1.5	-2.2	-1.6	-1.3
Pack years of smoking	1.7	2.4	3.6	-1.6	-1.5	-1.9	-1.6	-1.5	-1.4	-1.7	-1.4	-1.3	-1.6	-1.7	-1.9	-0.9	-1.8	-1.7	-1.7	-1.5	-1.5	-1.4
Alzheimer’s Disease (including proxy)	1.6	2.3	3.8	1.0	1.8	1.8	1.5	1.4	1.5	1.6	1.7	1.1	1.8	1.5	2.0	1.3	1.8	1.6	1.6	1.0	1.3	1.0
Irritable Bowel Disease (IBD)	1.6	3.8	6.3	-1.8	-2.1	-2.0	-2.2	-1.5	-2.5	-2.4	-1.3	-2.1	-1.9	-1.9	-2.3	-0.6	-1.9	-2.0	-2.5	-1.2	-2.4	-1.2
Hearing difficulty/problems: Yes	1.6	2.4	7.3	1.6	1.6	0.8	1.7	1.3	1.6	1.5	1.0	2.7	1.3	0.8	1.1	0.8	2.1	1.4	1.6	1.6	1.9	1.9
Vitamin and mineral supplements	1.6	2.2	3.6	1.6	1.4	1.5	1.5	1.3	1.7	1.8	0.9	1.8	1.3	1.5	1.9	0.4	1.7	1.6	1.8	1.0	1.8	1.1
Medication: Co-codamol	1.6	1.8	3.1	1.4	1.4	1.4	1.5	1.6	1.8	1.2	1.2	0.6	1.4	1.2	1.0	1.7	1.3	1.7	1.5	0.9	1.6	0.5
Medication: Atenolol	1.6	2.1	7.3	-1.1	-1.2	-0.9	-1.1	-1.4	-0.6	-1.8	-1.3	-2.7	-1.3	-1.5	-1.3	-0.8	-1.4	-1.3	-1.5	-1.2	-1.7	-1.8
Mouth/teeth dental problems: Dentures	1.6	2.6	4.1	-1.3	-1.9	-1.2	-1.5	-1.8	-1.3	-1.8	-1.6	-1.4	-1.8	-2.0	-2.0	-1.5	-2.0	-1.8	-1.8	-1.1	-1.5	-1.0
Exposure to tobacco smoke at home	1.6	1.8	2.7	1.5	1.6	1.4	1.5	1.4	1.7	1.2	1.1	1.0	1.3	1.0	1.3	1.0	1.5	1.4	1.4	1.3	1.6	1.0
Overall health rating	1.6	3.4	5.8	1.4	2.4	2.2	2.3	1.5	2.4	1.4	1.9	0.3	2.1	1.7	2.1	1.4	2.0	2.0	1.8	1.8	1.6	1.3
Alcohol drinker status: Previous	1.6	1.8	3.5	-0.8	-1.4	-1.1	-1.1	-1.8	-0.3	-1.7	-1.5	-0.5	-1.4	-1.9	-1.4	-1.9	-1.4	-1.5	-1.6	-0.9	-1.0	-1.1
Leg fat mass (left)	1.6	6.3	10.9	-3.1	-2.5	-2.2	-2.2	-2.9	-1.4	-2.2	-3.0	-3.2	-2.3	-2.0	-1.5	-3.3	-3.0	-2.5	-2.0	-2.4	-2.6	-2.4
Schizophrenia vs Biploar Disorder	1.5	1.9	4.9	1.1	1.5	1.0	1.4	1.6	-0.1	1.2	1.7	0.9	1.3	1.1	0.3	2.2	1.7	1.3	1.2	1.5	1.3	2.2
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	2.3	-1.3	-1.4	-1.5	-1.4	-1.2	-1.0	-1.4	-1.5	-1.3	-1.5	-1.4	-1.4	-1.0	-1.1	-1.3	-1.3	-1.5	-1.3	-1.2
Supplements: Vitamin C	1.5	1.8	4.2	-1.2	-1.5	-0.9	-1.5	-1.3	-1.0	-1.6	-0.9	-2.0	-1.2	-1.2	-1.3	-0.6	-1.8	-1.3	-1.5	-1.1	-1.6	-1.4
Medication: Levothyroxine sodium	1.4	2.4	5.1	-1.4	-1.8	-1.7	-1.5	-1.9	-0.9	-1.4	-1.7	-1.0	-1.6	-1.6	-1.2	-2.3	-1.7	-1.6	-1.4	-1.5	-1.2	-1.5
Leg fat mass (right)	1.4	5.2	9.7	-2.9	-2.2	-2.0	-2.0	-2.7	-1.3	-1.9	-2.7	-3.1	-2.0	-1.7	-1.2	-3.1	-2.7	-2.2	-1.8	-2.2	-2.4	-2.3
Risk taking	1.4	2.0	5.1	-1.6	-1.4	-1.3	-1.6	-1.2	-2.1	-1.5	-0.6	-2.2	-1.1	-0.8	-1.2	-0.4	-1.7	-1.5	-1.6	-0.8	-1.9	-0.9
Heel T-Score	1.3	10.3	23.0	1.6	4.1	2.6	2.9	3.1	2.8	2.7	3.5	1.9	3.9	4.0	4.8	2.1	4.0	3.3	3.0	3.8	2.1	2.4
Medication: Metformin	1.3	1.8	2.7	-1.4	-1.6	-1.2	-1.3	-1.3	-1.3	-1.2	-1.6	-0.9	-1.3	-1.4	-1.6	-1.6	-1.6	-1.4	-1.2	-1.6	-1.0	-0.9
Eye problems/disorders: None of the above	1.3	1.6	2.6	-1.0	-1.2	-1.4	-1.4	-1.3	-1.6	-1.4	-0.9	-0.7	-1.6	-1.5	-1.6	-0.8	-0.8	-1.5	-1.5	-0.8	-1.2	-0.6
Pain experienced in last month	1.3	2.2	3.4	-1.4	-1.6	-1.1	-1.7	-1.5	-1.7	-1.8	-1.3	-1.1	-1.4	-1.6	-1.8	-1.3	-1.1	-1.6	-1.9	-1.0	-1.7	-0.9
Mouth/teeth dental problems	1.2	1.9	3.8	-2.0	-1.0	-1.8	-1.8	-1.2	-1.9	-1.1	-1.0	-0.4	-1.3	-1.2	-1.0	-1.4	-1.0	-1.4	-1.5	-1.7	-1.4	-0.9
Breastfed as a baby	1.2	1.5	3.9	2.0	1.4	1.3	1.5	0.9	1.8	0.7	0.7	1.4	0.9	0.3	0.4	0.9	1.5	1.2	1.0	1.4	1.5	1.0
Arm fat percentage (left)	1.2	4.6	8.5	1.8	2.6	2.4	2.5	1.8	2.5	2.1	1.9	0.4	2.3	2.6	2.9	1.4	2.1	2.3	2.4	2.2	1.9	1.3
Irritability	1.2	2.1	7.6	1.3	1.5	0.4	1.6	1.7	0.6	1.4	0.6	1.6	1.1	1.0	0.5	1.6	2.8	1.4	1.7	0.8	1.6	1.9
Bipolar Disorder (2018)	1.1	1.7	3.9	-2.0	-1.3	-0.7	-1.3	-1.4	-0.9	-0.9	-1.0	-1.8	-0.8	-0.7	-0.4	-1.5	-1.9	-1.2	-1.1	-1.6	-1.6	-1.6
Mean Putamen Volume	1.1	1.2	2.6	-1.3	-1.4	-0.7	-1.2	-1.1	-0.5	-1.2	-0.9	-0.9	-1.0	-1.0	-0.8	-1.5	-1.6	-1.1	-1.2	-0.8	-0.9	-1.2
Mineral and other dietary supplements	1.1	1.4	2.9	-1.5	-1.3	-1.3	-1.4	-1.2	-1.7	-0.7	-0.8	-0.4	-1.3	-1.0	-1.0	-1.3	-1.0	-1.2	-1.1	-1.7	-1.1	-0.7
Bipolar Disorder or Schizophrenia	1.0	2.5	5.8	-2.1	-1.4	-1.0	-1.5	-1.8	-1.0	-1.6	-1.3	-2.4	-1.1	-1.0	-0.4	-1.6	-1.7	-1.4	-1.6	-1.4	-2.1	-1.9
Hypothyroidism (self reported)	1.0	2.4	3.7	-1.9	-1.6	-1.4	-1.7	-1.6	-1.4	-1.4	-1.2	-1.5	-1.6	-1.4	-1.2	-1.7	-1.9	-1.6	-1.6	-1.6	-1.5	-1.5
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	3.4	1.2	1.6	0.7	1.5	0.9	1.0	1.0	0.9	0.2	1.0	0.8	1.0	1.5	1.8	1.2	1.2	0.7	0.9	1.0
Pack years adult smoking proportion	1.0	1.5	3.0	-1.4	-1.1	-1.4	-1.2	-1.0	-1.3	-1.3	-1.0	-1.2	-1.2	-1.3	-1.7	-0.3	-1.5	-1.3	-1.3	-1.1	-1.2	-1.0
Wheeze or whistling in the chest in last year	1.0	1.7	3.2	-0.9	-1.3	-0.9	-1.0	-1.6	0.3	-1.6	-1.6	-1.0	-1.3	-1.7	-1.3	-1.8	-1.8	-1.2	-1.3	-0.9	-1.0	-1.4
Emphysema/chronic bronchitis	1.0	1.2	2.3	1.2	1.3	1.1	1.2	1.3	0.8	0.8	1.0	0.3	1.1	1.3	0.9	1.5	1.4	1.1	0.9	1.2	0.7	0.8
Tinnitus: Yes, now most or all of the time	1.0	1.2	2.8	-0.7	-1.3	-1.7	-1.0	-1.1	-0.6	-1.0	-1.2	-0.5	-1.2	-1.1	-1.1	-1.3	-1.0	-1.2	-1.0	-1.0	-0.7	-1.0
Intelligence (Savage-Jansen 2018)	0.9	2.8	6.8	-2.0	-1.7	-2.1	-2.0	-1.8	-1.9	-1.2	-1.9	-0.2	-1.7	-1.7	-1.4	-2.6	-1.2	-1.8	-1.4	-1.7	-1.4	-0.6
Reaction Time	0.9	1.8	4.2	1.2	1.3	2.0	1.4	1.2	2.0	1.1	1.1	0.2	1.4	1.4	2.0	1.2	1.3	1.4	1.4	1.0	1.0	0.1
Crohns Disease (2012)	0.9	1.4	2.3	-1.0	-1.1	-1.3	-1.5	-0.9	-1.4	-1.4	-0.9	-1.2	-1.4	-1.2	-1.2	-0.3	-0.8	-1.2	-1.5	-1.2	-1.5	-0.9
HbA1C	0.9	1.0	1.7	1.1	0.9	1.3	1.1	0.9	1.3	0.9	0.9	0.7	0.8	0.9	0.9	1.1	1.1	1.1	1.0	0.9	1.0	0.6
Type 2 Diabetes (T2D) (2012)	0.9	1.1	2.1	-1.5	-1.1	-1.3	-1.4	-0.9	-1.3	-0.7	-0.6	0.1	-1.0	-1.1	-0.9	-1.2	-1.2	-1.0	-1.0	-1.2	-1.0	-0.4
Arm fat percentage (right)	0.9	3.6	7.7	1.5	2.4	2.2	2.2	1.5	2.5	1.6	1.6	-0.1	2.1	2.3	2.8	1.1	1.9	2.0	2.0	2.1	1.4	1.0
Medication for pain relief, constipation, heartburn	0.9	1.6	4.2	-1.3	-1.1	-1.4	-1.8	-0.9	-2.1	-1.4	-0.6	-0.8	-1.3	-1.0	-1.3	-0.4	-0.9	-1.4	-1.6	-1.0	-1.5	-1.1
Supplements: Fish oil (including cod liver oil)	0.9	1.1	2.7	0.9	1.2	1.2	1.1	1.0	1.7	0.8	0.6	0.6	1.2	1.1	1.4	0.8	1.0	1.1	1.0	1.1	0.8	0.4
Alcohol drinker status: Never	0.9	1.1	2.2	1.4	1.1	1.1	1.0	0.9	1.5	0.9	1.0	0.9	0.9	1.1	1.4	0.6	0.7	1.0	0.8	1.2	1.0	0.0
Depression (Nagel 2018)	0.8	1.2	2.2	-1.1	-0.7	-1.3	-0.8	-1.3	-0.3	-1.3	-1.5	-1.2	-1.1	-1.3	-1.0	-1.4	-0.8	-1.1	-0.9	-1.0	-1.0	-1.1
Neuroticism (Nagel 2018)	0.8	1.8	6.4	1.0	1.8	0.6	1.8	1.4	0.9	1.1	0.5	1.0	1.2	0.7	0.5	1.5	2.5	1.3	1.6	1.1	1.4	2.1
Verbal and Numeric Reasoning (VNR)	0.8	1.8	3.8	-1.5	-1.3	-2.0	-1.6	-1.3	-1.7	-1.1	-1.5	-0.2	-1.4	-1.2	-1.3	-1.9	-1.1	-1.6	-1.2	-1.0	-1.2	-0.6
Respiratory disease	0.8	1.7	2.7	-1.3	-1.2	-1.2	-1.4	-1.4	-1.2	-1.7	-1.0	-1.2	-1.2	-1.4	-1.4	-1.3	-1.5	-1.4	-1.6	-0.7	-1.4	-1.0
Fed-up feelings	0.8	1.5	2.9	1.0	1.6	1.4	1.7	1.1	1.3	1.1	0.6	0.2	1.4	1.1	0.9	0.8	1.5	1.3	1.5	1.4	1.2	1.1
Number of incorrect matches in round	0.8	1.3	3.0	0.9	1.0	1.0	1.1	1.0	0.6	1.5	1.1	1.7	1.2	1.3	1.5	0.5	1.2	1.1	1.2	1.0	1.2	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	2.9	0.6	1.3	0.8	1.4	1.0	1.6	1.2	0.3	0.1	1.0	1.3	1.4	0.8	1.4	1.3	1.7	0.2	1.2	0.2
Allergy	0.8	1.8	2.9	1.3	1.4	1.4	1.5	1.4	1.4	1.7	1.0	1.2	1.2	1.3	1.5	1.1	1.5	1.5	1.7	0.5	1.6	0.8
Asthma	0.8	1.6	3.6	-0.9	-1.1	-0.9	-1.2	-1.6	0.1	-1.5	-1.3	-0.9	-1.2	-1.4	-0.9	-1.9	-1.5	-1.2	-1.3	-0.7	-1.1	-1.5
Medication: Ventolin 100micrograms inhaler	0.8	1.0	3.0	-0.3	-1.0	-0.3	-0.7	-1.3	0.9	-1.3	-1.1	-1.2	-0.8	-1.0	-0.2	-1.7	-1.1	-0.8	-1.0	-0.5	-0.9	-1.7
Body fat percentage	0.8	3.1	6.0	1.4	2.1	1.9	2.1	1.4	2.2	1.8	1.4	0.4	1.9	2.1	2.4	0.8	1.7	1.9	2.1	1.8	1.6	1.0
Neck or shoulder pain in last month	0.8	1.2	2.3	-1.4	-0.8	-1.2	-0.8	-1.4	-0.0	-1.1	-1.4	-1.2	-1.0	-1.1	-0.3	-1.5	-0.9	-1.0	-0.8	-1.0	-1.1	-1.3
Had major operations	0.8	0.9	1.6	1.3	0.9	1.1	1.0	1.0	1.0	1.2	0.8	1.2	0.9	0.7	0.7	0.8	0.8	1.0	1.1	0.7	1.1	1.0
Medication: Aspirin	0.8	1.1	3.5	0.7	1.1	1.3	1.3	0.6	1.7	1.0	0.7	-0.0	1.2	1.4	1.9	0.2	0.6	0.9	1.2	1.0	0.8	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	1.7	1.3	0.8	0.8	1.2	0.7	1.2	0.8	1.0	1.0	0.8	0.3	0.7	0.6	1.1	1.0	0.8	0.9	1.2	1.2
Diabetes diagnosed by doctor	0.8	1.3	2.6	-1.2	-1.4	-1.1	-1.1	-1.2	-0.8	-0.9	-1.1	-0.6	-1.1	-1.1	-1.2	-1.6	-1.6	-1.1	-1.1	-1.3	-0.8	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	2.2	-1.1	-1.3	-1.3	-0.7	-1.1	-1.0	-0.5	-1.5	-0.7	-1.2	-1.0	-1.1	-1.1	-0.8	-1.1	-0.5	-1.0	-0.6	-0.3
Depressed Affect (Nagel 2018)	0.7	1.4	3.3	1.0	1.5	0.9	1.6	1.2	0.8	1.1	0.6	0.7	1.2	0.7	0.5	1.0	1.8	1.3	1.4	1.1	1.4	1.7
Stomach or abdominal pain in last month	0.7	0.9	2.0	0.5	1.0	0.6	1.2	0.8	1.1	1.3	0.7	0.7	1.0	0.7	1.2	0.6	1.1	1.0	1.4	0.3	1.2	0.8
Comparative body size at age 10	0.7	2.0	4.5	0.7	1.4	1.6	1.6	1.4	1.1	1.8	1.1	0.3	1.7	2.1	1.8	1.0	0.9	1.5	1.9	1.2	1.3	1.1
Age at first live birth	0.7	1.2	1.8	-1.1	-1.0	-1.4	-1.3	-1.2	-1.1	-1.1	-1.2	-0.9	-1.2	-1.0	-0.9	-1.1	-0.9	-1.3	-1.0	-1.1	-1.2	-0.9
Medication: Allopurinol	0.7	0.9	1.7	0.8	1.0	0.8	1.0	1.0	0.7	1.0	0.8	0.6	1.0	1.2	1.0	0.9	1.0	1.0	1.1	1.3	0.9	0.8
Pulse rate, automated reading	0.7	2.3	4.2	2.0	1.4	2.1	1.6	1.5	2.0	1.3	1.6	1.4	1.4	1.0	0.9	1.8	1.0	1.6	1.2	1.3	1.8	0.6
Asthma (self-reported)	0.7	1.5	3.3	-0.7	-1.1	-0.9	-1.2	-1.5	0.2	-1.5	-1.2	-1.0	-1.2	-1.2	-0.8	-1.8	-1.6	-1.2	-1.2	-0.6	-1.0	-1.6
Medication: Atorvastatin	0.7	0.8	1.9	0.8	1.2	1.1	1.0	0.4	1.2	0.8	0.8	0.6	1.0	1.0	1.4	0.1	0.7	0.8	0.8	1.4	0.6	0.5
Unable to work because of sickness or disability	0.7	0.8	2.9	0.7	1.2	1.0	1.1	1.1	0.7	0.6	0.7	-0.3	0.9	1.1	0.6	1.7	1.0	1.0	0.9	0.6	0.6	0.5
Age at First Birth	0.6	0.9	2.0	-1.4	-0.6	-1.1	-1.3	-0.9	-1.2	-0.9	-0.5	-0.6	-0.8	-1.0	-0.7	-0.9	-0.9	-0.9	-1.2	-0.7	-1.3	-0.5
Body Mass Index (BMI) (2010)	0.6	0.9	2.4	-1.5	-0.7	-0.5	-0.8	-0.9	-0.4	-0.6	-0.7	-1.6	-0.5	0.1	0.4	-1.4	-1.3	-0.7	-0.6	-1.0	-1.1	-1.3
Schizophrenia (2014)	0.6	1.3	2.9	-1.3	-0.9	-0.8	-1.1	-1.5	-0.9	-1.4	-1.0	-1.7	-0.9	-0.8	-0.7	-1.1	-1.1	-1.2	-1.3	-0.7	-1.6	-1.2
Smoking Status	0.6	1.4	3.0	1.5	0.9	0.9	1.4	1.2	0.9	1.3	0.5	1.6	0.8	0.5	0.2	1.2	1.5	1.2	1.4	0.6	1.7	1.4
Average weekly fortified wine intake	0.6	0.7	1.4	-0.8	-0.8	-1.2	-1.1	-0.9	-1.2	-0.9	-0.6	-0.4	-1.0	-0.7	-0.7	-0.8	-0.7	-1.0	-1.0	-0.5	-0.9	-0.4
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.0	-1.0	-1.1	-0.4	-0.9	-1.0	-0.4	-1.4	-0.6	-1.0	-0.8	-1.3	-0.9	-0.7	-0.8	-0.8	-1.3	-0.3	-1.1	-0.4
Neuroticism score	0.6	1.3	4.4	0.8	1.4	0.8	1.6	1.2	0.9	0.9	0.4	0.2	1.2	0.7	0.5	1.3	2.1	1.2	1.4	0.8	1.0	1.2
Father’s age at death	0.6	0.8	1.9	-0.8	-1.1	-1.3	-1.1	-0.8	-0.8	-0.2	-0.9	0.9	-1.1	-0.5	-0.4	-1.4	-0.8	-0.9	-0.5	-1.4	-0.3	-0.6
Loud music exposure frequency	0.6	0.7	1.7	1.2	0.9	1.0	0.9	0.6	1.1	-0.1	0.7	-0.8	0.8	0.4	0.5	1.3	1.0	0.7	0.2	1.3	0.1	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	3.9	-0.6	-1.0	-0.3	-0.5	-0.8	0.1	-0.8	-1.1	-2.0	-0.7	-0.5	-0.6	-0.8	-1.4	-0.6	-0.5	-0.7	-0.7	-1.2
Medication: Omeprazole	0.6	0.7	2.3	0.7	0.4	0.7	0.8	0.3	1.5	1.0	0.7	1.4	0.7	0.4	1.2	-0.5	0.4	0.7	1.0	0.6	1.2	0.8
Mean time to correctly identify matches	0.6	1.1	2.8	1.0	1.0	1.5	1.0	0.9	1.7	0.8	0.8	0.2	1.0	1.0	1.7	0.9	1.1	1.0	1.0	0.9	0.8	0.0
Leg pain on walking	0.6	0.8	3.2	0.8	0.5	0.0	1.0	0.8	-0.4	1.2	0.8	1.2	0.6	0.6	-0.1	0.7	0.9	0.7	1.0	0.7	1.3	1.8
Qualifications: nursing, teaching	0.6	0.9	2.0	-0.9	-1.0	-0.6	-0.8	-1.2	-0.0	-1.0	-1.1	-1.4	-0.9	-0.8	-0.3	-1.1	-1.1	-0.8	-0.8	-0.9	-1.1	-1.1
Osteoporosis (self-reported)	0.6	0.7	1.5	0.8	0.9	0.5	0.7	1.0	-0.2	1.1	1.0	0.9	0.7	0.7	0.4	1.1	0.9	0.7	0.9	0.7	1.0	1.2
Commuting to job workplace: Public transport	0.6	0.7	1.6	-0.3	-1.3	-1.0	-0.9	-1.0	-0.4	-0.9	-0.7	0.1	-1.1	-1.2	-0.9	-1.2	-0.6	-0.8	-1.0	-0.6	-0.5	-0.5
Schizophrenia (2018)	0.5	1.0	2.6	-1.2	-0.7	-0.7	-0.9	-1.3	-0.5	-1.3	-0.8	-1.6	-0.7	-0.7	-0.3	-1.0	-0.7	-0.9	-1.2	-0.5	-1.5	-1.2
Crohns Disease (2017)	0.5	1.1	1.8	-0.7	-1.4	-0.8	-1.2	-0.9	-1.0	-1.2	-0.7	-1.1	-1.1	-1.0	-1.1	-0.5	-1.2	-1.0	-1.4	-0.8	-1.2	-0.7
Fasting Glucose	0.5	0.6	1.3	-0.6	-1.2	-0.9	-0.8	-1.1	-0.6	-0.8	-0.6	0.2	-0.8	-1.0	-0.8	-0.8	-0.4	-1.0	-0.8	-0.4	-0.6	-0.3
Serious illness, injury or assault to yourself	0.5	0.6	1.3	0.7	0.7	1.1	0.9	0.5	1.1	0.8	0.8	0.1	0.9	0.9	1.1	0.5	0.4	0.9	0.9	0.6	0.7	0.1
Noisy workplace	0.5	0.6	1.4	0.7	1.1	0.6	0.9	0.6	0.5	0.7	0.6	0.3	0.7	0.9	0.9	0.6	1.2	0.6	0.7	0.8	0.6	0.7
Birth weight of first child	0.5	0.9	1.4	-0.8	-0.8	-1.2	-0.9	-1.2	-0.8	-1.0	-0.9	-1.0	-1.1	-1.1	-0.9	-0.7	-0.3	-0.9	-1.0	-1.1	-1.1	-0.7
Medication: Paracetamol	0.5	0.8	1.9	0.8	0.8	1.0	1.3	0.8	1.4	1.0	0.4	0.4	0.9	0.6	0.7	0.4	0.9	1.1	1.2	0.4	1.1	0.9
Alcohol intake frequency.	0.5	1.1	3.8	1.3	1.2	1.1	1.3	0.9	2.0	0.5	0.4	0.6	1.0	0.8	1.0	0.6	1.3	1.0	0.9	1.0	1.0	0.1
Chest pain or discomfort	0.5	0.8	3.3	-0.7	-0.7	-0.6	-0.5	-1.3	0.5	-0.9	-1.3	-0.7	-0.7	-1.3	-0.6	-1.8	-1.0	-0.8	-0.6	-0.4	-0.4	-0.5
Wears glasses or contact lenses	0.5	0.6	2.7	0.7	0.8	-0.4	0.5	0.5	-0.3	0.4	0.4	1.5	0.2	-0.1	-0.2	0.3	1.4	0.3	0.4	0.6	0.9	1.6
Pain type(s) experienced in last month: Hip pain	0.5	0.7	2.4	-0.9	-0.1	-0.4	-0.3	-0.9	0.9	-0.4	-0.9	-1.5	-0.3	-0.0	0.9	-1.3	-0.8	-0.3	-0.1	-0.9	-0.6	-1.6
Age started oral contraceptive pill	0.5	0.6	2.0	1.0	0.5	-0.1	0.6	0.5	-0.4	-0.1	0.5	1.2	0.3	-0.2	-0.8	1.2	1.4	0.3	0.0	1.4	0.4	1.4
Alzheimer’s Disease (in mother)	0.4	0.4	1.9	0.3	0.9	0.7	0.7	0.4	1.4	0.4	0.4	0.0	0.7	0.2	1.0	0.3	1.0	0.8	0.7	0.0	0.5	0.1
Primary Biliary Cirrhosis	0.4	0.6	1.8	-0.8	-0.8	-0.2	-0.6	-0.7	-0.1	-0.8	-0.8	-1.3	-0.5	-0.5	-0.6	-0.5	-1.3	-0.6	-0.7	-0.5	-0.9	-1.1
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.1	0.8	0.8	0.5	0.7	0.7	0.4	0.3	0.8	0.3	0.7	0.7	0.5	0.9	0.8	0.6	0.5	1.1	0.5	0.7
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.5	-0.8	-1.0	-0.8	-0.9	-1.1	-0.7	-1.2	-0.7	-1.1	-0.7	-0.8	-0.8	-0.9	-1.1	-1.0	-1.1	-0.2	-1.2	-0.7
Heart attack	0.4	0.5	4.6	0.6	0.4	0.6	0.9	-0.4	2.1	0.2	-0.3	-0.1	0.4	0.1	1.2	-0.9	0.4	0.4	0.6	0.6	0.4	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.5	1.8	-0.7	-0.7	-0.4	-0.2	-0.9	0.4	-0.7	-1.3	-1.1	-0.5	-0.7	-0.4	-1.3	-0.8	-0.6	-0.2	-0.5	-0.4	-0.7
Glaucoma (self-reported)	0.4	0.5	2.0	0.1	0.2	0.3	0.3	1.0	-0.9	1.1	0.6	1.0	0.6	0.7	-0.2	0.8	-0.1	0.6	0.8	-0.1	0.9	1.4
Number of full brothers	0.4	0.5	2.5	-0.1	0.5	0.2	0.0	0.9	-1.4	0.2	1.1	0.5	0.4	-0.1	-0.7	1.6	0.5	0.3	-0.0	0.4	0.3	1.4
Worry too long after embarrassment	0.4	0.7	3.4	0.6	1.0	0.3	1.0	0.9	0.5	0.7	0.2	0.3	0.8	0.6	0.7	0.9	1.8	0.8	1.0	0.5	0.6	0.7
Pulse wave peak to peak time	0.4	0.5	0.9	-0.5	-0.7	-0.5	-0.7	-0.5	-0.8	-0.6	-0.6	-1.0	-0.6	-0.5	-0.8	-0.2	-0.7	-0.6	-0.8	-0.9	-0.9	-0.7
Medication: Seretide 50 evohaler	0.4	0.5	2.0	-0.0	-0.8	-0.3	-0.5	-1.0	0.7	-0.9	-0.4	0.2	-0.7	-1.4	-0.5	-1.2	-0.5	-0.6	-0.8	-0.3	-0.2	-0.4
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.3	0.6	0.4	0.7	0.8	0.0	1.2	0.6	0.2	0.2	0.7	0.7	1.1	-0.3	0.0	0.5	0.8	1.0	0.7	0.1
Illnesses of siblings: Diabetes	0.4	0.5	2.3	-0.7	-0.4	-0.2	-0.5	-0.6	0.8	-0.8	-0.6	-1.4	-0.2	0.1	0.7	-0.9	-0.4	-0.3	-0.5	-0.6	-1.0	-1.5
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.4	0.5	0.4	0.7	0.6	0.2	1.5	0.7	0.4	0.7	0.6	0.5	1.2	-0.5	0.1	0.6	0.7	0.4	0.8	0.1
Supplements: Calcium	0.4	0.4	2.5	-0.6	-0.3	-0.0	-0.3	-0.4	0.2	-0.9	-0.7	-1.6	-0.3	-0.4	-0.2	-0.1	-0.6	-0.4	-0.5	-0.5	-0.9	-1.1
Cardiovascular Disease	0.3	1.1	4.4	0.7	1.1	1.6	0.9	0.8	2.1	0.8	0.6	-0.5	1.2	1.4	1.9	0.2	0.4	1.1	1.0	0.5	0.5	-0.6
Number of treatments/medications taken	0.3	0.5	4.4	0.2	0.4	0.9	0.6	-0.2	2.1	-0.1	-0.0	-1.1	0.5	0.4	1.1	-0.5	-0.1	0.5	0.2	0.2	-0.1	-1.0
Medication for hormone replacement therapy	0.3	0.3	1.7	0.8	0.2	0.3	0.5	0.7	0.1	0.2	0.7	0.4	0.4	0.2	-0.5	1.3	0.2	0.4	0.3	0.6	0.7	0.6
Trunk fat percentage	0.3	1.0	3.4	-1.3	-0.5	-0.7	-0.7	-1.3	-0.1	-0.9	-1.1	-1.8	-0.8	-0.6	0.0	-1.6	-0.8	-0.9	-0.7	-0.9	-1.2	-1.3
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.6	0.9	0.5	1.3	0.7	0.3	1.0	-0.0	0.4	0.0	0.5	-0.0	0.1	0.4	0.4	0.6	0.2	1.0	0.4	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	4.7	-0.6	0.9	0.7	0.4	0.1	1.0	0.7	0.4	0.4	0.8	1.0	2.2	-0.9	0.8	0.6	0.7	0.4	0.1	0.1
Chronic bronchitis/emphysema (father)	0.3	0.3	1.1	0.4	0.6	1.0	0.8	0.2	1.1	0.4	0.5	-0.0	0.7	0.4	0.8	0.2	0.4	0.7	0.6	0.5	0.6	0.2
Hearing difficulty/problems with background noise	0.3	0.5	2.3	0.3	0.7	-0.3	0.6	0.5	0.0	0.6	0.5	1.5	0.5	-0.2	0.0	0.5	1.3	0.6	0.6	0.1	0.8	1.5
Had other major operations	0.3	0.3	0.9	0.0	0.8	0.8	0.8	0.5	0.9	0.2	0.5	0.1	0.8	0.5	0.6	0.6	0.4	0.7	0.4	0.5	0.2	0.1
Time employed in main current job	0.3	0.3	0.7	-0.7	-0.9	-0.6	-0.6	-0.7	-0.2	-0.3	-0.6	-0.3	-0.6	-0.5	-0.3	-0.7	-0.8	-0.4	-0.4	-0.8	-0.4	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	2.7	-1.4	-0.2	-0.3	-0.2	-0.8	0.1	-0.5	-1.0	-1.6	-0.2	-0.3	0.4	-1.2	-0.2	-0.3	-0.1	-0.7	-0.8	-0.5
Falls in the last year	0.3	0.4	1.0	0.5	0.8	0.6	0.8	0.4	1.0	0.7	0.4	0.5	0.7	0.6	1.0	0.2	0.8	0.6	0.8	0.5	0.6	0.4
Depression (self-reported)	0.3	0.4	2.5	0.8	0.2	0.9	0.9	-0.1	1.6	0.3	-0.5	-0.4	0.2	0.1	0.2	0.0	-0.1	0.5	0.8	0.3	0.7	0.0
Illnesses of mother	0.3	0.4	1.4	-0.1	-0.8	-0.4	-0.7	-0.2	-0.8	-0.9	0.0	-0.2	-0.6	-1.0	-1.2	0.5	-0.5	-0.5	-1.0	-0.3	-0.5	-0.3
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.9	-0.0	0.7	-0.1	0.5	0.5	0.1	0.9	0.3	0.9	0.4	0.8	0.7	0.2	1.0	0.5	0.8	0.0	0.6	0.3
Gout (self-reported)	0.3	0.5	1.3	0.7	0.6	0.4	0.7	0.6	0.2	0.7	0.6	1.0	0.6	0.7	0.6	0.3	0.7	0.6	0.6	1.1	0.6	1.0
Number of children fathered	0.3	0.4	2.1	-0.6	-0.6	-0.7	-0.6	-0.8	-0.3	-0.1	-0.8	0.1	-0.5	-0.2	0.1	-1.4	-0.7	-0.7	-0.3	-0.6	-0.4	-0.6
Medication: Blood pressure	0.3	0.5	2.0	-0.7	-0.5	0.1	-0.4	-0.9	0.8	-0.3	-0.6	-0.9	-0.3	-0.1	0.6	-1.4	-0.9	-0.4	-0.3	-0.9	-0.7	-1.2
Angina (self-reported)	0.3	0.4	1.7	-0.5	-0.5	-0.1	-0.0	-0.8	0.7	-0.7	-0.8	-1.0	-0.2	-0.3	0.0	-1.3	-1.0	-0.4	-0.4	-0.1	-0.4	-0.7
Heart disease (mother)	0.3	0.4	1.3	-0.3	0.8	0.5	0.6	0.4	0.8	0.4	0.2	-1.1	0.7	1.1	1.1	0.2	0.3	0.6	0.7	0.1	0.0	-0.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.0	0.6	0.3	0.5	0.5	0.4	0.7	0.5	0.4	0.5	0.6	0.7	0.8	-0.0	0.5	0.5	0.5	1.0	0.4	0.4
Illnesses of father: Heart disease	0.3	0.4	1.7	0.2	0.4	0.5	0.8	0.3	1.2	0.7	-0.0	-0.2	0.7	0.9	1.3	-0.4	0.3	0.6	1.0	0.4	0.6	0.3
Long-standing illness, disability or infirmity	0.3	0.5	1.6	-0.7	-0.5	-0.5	-0.2	-1.0	0.5	-0.9	-1.0	-1.3	-0.5	-1.0	-0.4	-0.9	-0.8	-0.6	-0.4	-0.5	-0.6	-0.7
Ever had bowel cancer screening	0.3	0.3	2.1	-0.3	-0.1	-0.5	-0.1	-0.1	-0.3	-0.8	-0.7	-1.4	-0.3	-0.1	-0.6	0.3	-0.3	-0.4	-0.4	-0.2	-0.6	-0.7
Eye problems/disorders: Cataract	0.3	0.4	0.9	-1.0	-0.7	-0.4	-0.4	-0.7	-0.2	-0.4	-0.8	-0.4	-0.3	-0.6	-0.3	-1.0	-0.8	-0.5	-0.4	-0.8	-0.6	-0.5
Back pain experienced in last month	0.3	0.4	1.8	-0.4	-0.7	-1.2	-0.3	-0.4	-1.3	-0.0	-0.3	0.1	-0.6	-0.6	-1.0	0.1	-0.4	-0.6	-0.3	-0.3	-0.1	0.7
Medication: Aspirin	0.3	0.4	1.6	0.2	0.5	0.7	0.7	-0.0	1.2	0.4	0.2	-0.5	0.6	0.7	1.2	-0.4	0.1	0.4	0.6	0.5	0.3	-0.1
Number of self-reported non-cancer illnesses	0.3	0.5	2.6	-0.7	-0.3	0.1	-0.3	-0.7	0.6	-0.7	-0.5	-1.6	-0.3	-0.4	0.1	-0.5	-0.8	-0.3	-0.5	-0.6	-0.8	-1.2
Miserableness	0.3	0.5	1.0	0.6	0.8	0.6	0.9	0.7	0.6	0.7	0.4	-0.1	0.7	0.7	0.4	0.8	0.7	0.8	1.0	0.4	0.9	0.4
Guilty feelings	0.3	0.4	1.2	1.0	0.6	0.4	1.1	0.4	1.1	0.4	-0.5	-0.0	0.5	0.4	-0.0	0.3	0.5	0.6	0.9	0.7	0.7	0.3
Medication: Lisinopril	0.3	0.3	1.9	-0.1	0.1	0.6	0.6	-0.2	1.4	0.4	-0.4	-0.5	0.3	0.6	1.0	-0.9	-0.2	0.4	0.7	-0.0	0.2	-0.4
Ever smoked	0.3	0.5	2.1	1.1	0.5	0.6	0.8	0.9	0.1	0.5	0.5	0.2	0.5	0.1	-0.2	1.4	1.1	0.7	0.6	0.3	0.7	0.9
Vascular/heart problems diagnosed by doctor	0.3	0.9	4.9	-0.0	-0.7	-1.6	-0.7	-0.1	-2.2	-0.3	0.1	1.0	-0.8	-1.0	-1.7	0.6	0.1	-0.7	-0.6	-0.3	0.0	0.9
Basal cell carcinoma (self-reported)	0.3	0.4	1.8	-0.3	0.5	-0.6	-0.2	-0.5	0.7	-0.3	-0.3	-0.3	-0.2	0.0	1.4	-0.6	1.0	-0.1	-0.1	-0.7	-0.6	-1.2
Heart attack/myocardial infarction (self-reported)	0.3	0.4	3.7	0.4	0.2	0.4	0.7	-0.5	1.9	0.0	-0.5	-0.2	0.1	-0.1	0.9	-1.0	0.2	0.2	0.4	0.4	0.2	-0.4
Worry (Nagel 2018)	0.2	0.3	2.5	-0.1	0.6	-0.4	0.6	0.3	0.3	-0.1	-0.2	0.1	0.2	-0.6	-0.3	0.5	1.6	0.3	0.3	0.2	0.3	1.2
Breast Cancer	0.2	0.4	1.1	0.7	0.1	1.0	0.5	0.2	1.0	0.5	0.3	1.0	0.6	0.7	0.6	-0.4	-0.3	0.5	0.5	0.9	0.6	-0.1
Ovarian Cancer	0.2	0.3	1.1	0.1	0.4	0.8	0.4	0.5	0.7	0.2	0.6	-0.4	0.6	0.9	1.0	0.4	0.4	0.6	0.3	0.3	0.1	0.1
Rheumatoid Arthritis	0.2	0.3	1.4	-0.3	-0.6	-0.3	-0.4	-0.2	-0.7	-0.6	-0.3	-0.0	-0.8	-1.0	-1.2	0.4	-0.2	-0.5	-0.7	-0.6	-0.3	0.3
Triglycerides	0.2	0.3	1.7	-0.2	0.3	0.9	0.1	0.3	0.1	0.3	1.0	-0.8	0.6	1.2	1.3	0.3	-0.1	0.4	0.1	0.3	-0.2	-0.3
Blood White Count	0.2	1.3	2.5	-1.4	-1.0	-1.0	-0.8	-1.4	0.1	-1.2	-1.2	-1.6	-0.9	-0.9	-0.4	-1.6	-1.5	-0.9	-0.9	-1.1	-1.0	-1.4
BMI	0.2	1.0	5.0	-1.1	-0.9	0.1	-0.4	-1.0	0.5	-0.4	-0.8	-2.2	-0.3	0.4	0.7	-1.8	-1.8	-0.5	-0.2	-0.3	-0.8	-1.3
Ever had hysterectomy (womb removed)	0.2	0.2	1.2	0.6	-0.1	0.4	0.0	-0.0	1.1	-0.5	-0.0	-0.2	-0.1	0.2	-0.1	-0.1	-0.6	0.1	-0.2	0.4	0.2	-0.9
High blood pressure	0.2	0.5	3.1	-0.1	0.4	1.3	0.3	-0.1	1.8	0.0	-0.3	-1.1	0.5	0.6	1.1	-0.7	-0.4	0.4	0.2	0.1	-0.3	-1.1
Supplements: Glucosamine	0.2	0.3	1.0	0.5	0.6	0.2	0.6	0.6	0.3	0.4	0.3	0.1	0.7	0.8	0.3	0.7	0.5	0.5	0.6	1.0	0.4	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.2	-1.2	-0.2	-0.5	-0.8	-0.9	-0.0	-0.6	-0.4	-0.5	-0.3	-0.2	0.9	-1.5	-0.3	-0.5	-0.5	-0.5	-0.9	-0.9
Financial difficulties in last 2 years	0.2	0.2	2.7	-0.3	-0.2	-0.3	-0.1	-0.1	-0.2	-0.5	-0.5	-1.6	-0.4	-0.3	-0.7	0.3	-0.3	-0.2	-0.1	-0.5	-0.2	-0.3
Pain all over the body in last month	0.2	0.2	1.0	-0.4	0.1	0.1	-0.1	-0.2	0.1	-0.7	-0.1	-1.0	-0.1	-0.4	-0.2	0.2	0.1	-0.1	-0.6	-0.3	-0.6	-0.6
Medication: Ramipril	0.2	0.2	0.7	-0.4	-0.3	-0.1	0.2	-0.5	0.7	-0.3	-0.7	-0.3	-0.2	-0.7	-0.3	-0.9	-0.0	-0.1	-0.1	-0.8	-0.2	-0.4
Illnesses of siblings	0.2	0.3	1.3	0.3	-0.6	-0.3	-0.2	-0.3	-1.0	-0.4	0.2	0.6	-0.6	-1.1	-1.2	0.3	0.0	-0.4	-0.6	0.0	0.1	0.7
Number of live births	0.2	0.3	1.1	0.4	0.6	0.7	0.5	0.8	0.4	0.4	0.7	0.1	0.6	0.6	0.6	1.0	0.5	0.6	0.4	0.3	0.4	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.6	-0.4	-0.3	-0.3	-0.4	-0.5	-0.4	-0.3	-0.3	0.6	-0.4	-0.7	-0.6	-0.8	-0.3	-0.5	-0.4	-0.4	-0.1	0.1
Medication: Cholesterol lowering	0.2	0.3	1.3	0.5	0.2	0.2	0.8	-0.1	1.2	0.9	0.1	0.4	0.4	0.4	1.0	-0.5	-0.1	0.5	0.8	-0.0	0.7	0.2
Prospective memory result	0.2	0.3	1.0	0.6	0.8	0.6	0.6	0.4	-0.1	0.2	1.0	0.2	0.5	0.3	0.3	0.8	0.5	0.4	0.0	1.0	0.2	0.6
Medication: Amlodipine	0.2	0.2	1.1	0.2	-0.1	0.3	-0.1	-0.6	1.0	-0.5	-0.2	-0.4	-0.2	-0.1	0.3	-0.8	-0.5	-0.2	-0.4	0.0	-0.3	-1.0
Exposure to tobacco smoke outside home	0.2	0.3	1.3	-0.6	-0.4	-0.3	-0.1	-0.5	0.6	-0.5	-1.1	-0.7	-0.5	-0.6	0.0	-0.6	0.3	-0.2	-0.0	-0.9	-0.3	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.5	-0.4	0.1	-0.1	-0.3	-0.6	0.5	-0.7	-0.3	-0.5	-0.1	-0.5	0.2	-0.7	-0.0	-0.3	-0.4	-0.1	-0.5	-0.7
Medication: Ibuprofen	0.2	0.2	0.9	-0.2	-0.6	-0.3	-0.2	-0.5	0.6	-0.3	-0.9	-0.0	-0.4	-0.4	-0.1	-0.8	-0.5	-0.2	-0.2	-0.6	-0.2	-0.6
Suffer from ‘nerves’	0.2	0.3	0.9	0.3	0.7	0.4	0.8	0.5	0.9	0.1	0.1	-0.1	0.6	-0.0	0.0	0.6	1.0	0.6	0.5	0.5	0.5	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	1.1	0.1	0.6	0.4	0.2	0.3	0.3	0.2	0.2	-0.8	0.2	0.9	1.0	0.4	0.5	0.3	0.1	-0.0	-0.4	-0.5
Hypertension (Self-reported)	0.2	0.6	2.5	-0.4	0.1	1.0	0.1	-0.4	1.6	-0.3	-0.6	-1.4	0.1	0.3	0.9	-0.9	-0.6	0.1	-0.0	-0.4	-0.6	-1.5
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.6	0.6	0.7	0.3	0.3	0.2	0.8	0.1	0.4	0.7	0.3	-0.1	0.3	0.2	0.7	0.3	0.0	0.6	0.2	0.4
Mood swings	0.2	0.3	1.0	0.3	1.0	0.4	0.8	0.7	0.4	0.2	-0.0	-0.3	0.5	0.3	-0.1	1.0	1.0	0.5	0.6	0.3	0.4	0.3
Loneliness, isolation	0.2	0.3	1.0	0.3	0.7	0.7	0.9	0.4	1.0	0.2	-0.2	-0.9	0.4	0.6	0.4	0.5	0.4	0.6	0.8	0.4	0.5	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	0.6	0.1	0.7	0.5	0.6	0.6	0.3	0.5	0.3	-0.3	0.5	0.6	0.5	0.7	0.4	0.5	0.8	0.1	0.6	0.5
Friendships satisfaction	0.2	0.2	1.2	-0.4	-0.2	0.2	0.0	-0.4	0.6	-0.2	-0.6	-1.1	-0.1	0.0	0.3	-0.6	-0.5	-0.1	0.0	-0.4	-0.3	-0.8
Illnesses of father: None of the above (group 1)	0.2	0.3	2.6	0.5	0.0	-0.6	-0.3	0.2	-0.7	0.1	0.4	1.6	-0.3	-0.4	-0.7	0.4	0.4	-0.1	-0.3	0.3	0.3	0.6
Financial situation satisfaction	0.2	0.2	0.7	0.3	0.5	0.2	0.7	0.3	-0.1	0.2	0.2	-0.3	0.3	-0.2	-0.3	0.8	0.8	0.4	0.3	0.3	0.3	0.7
Medication: Blood pressure	0.2	0.4	2.1	-0.1	-0.2	0.3	-0.0	-0.9	1.1	-0.6	-0.9	-0.5	-0.3	-0.6	-0.0	-1.5	-0.5	-0.3	-0.3	0.1	-0.4	-0.9
Illnesses of father: High blood pressure	0.2	0.3	1.1	-0.7	-0.2	0.2	-0.1	-0.2	0.4	-0.1	-0.6	-1.0	-0.0	0.4	0.5	-0.7	-0.6	-0.2	0.1	-0.7	-0.4	-1.1
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.6	-0.6	-0.2	-0.6	-0.4	-0.4	-0.2	-0.2	-0.6	-0.0	-0.3	-0.5	-0.1	-0.6	0.1	-0.3	-0.3	-0.8	-0.4	-0.1
Heart disease (siblings)	0.2	0.3	1.0	0.1	0.7	0.3	0.6	0.6	0.5	0.4	0.0	-0.5	0.6	1.0	0.6	0.6	0.3	0.6	0.7	0.1	0.3	-0.1
Neuroticism (2016)	0.1	0.1	0.8	-0.3	0.1	0.1	0.4	0.1	0.9	-0.0	-0.5	-0.7	0.2	-0.0	0.3	-0.2	0.2	0.4	0.4	-0.4	0.1	-0.3
Blood Red Count	0.1	0.9	4.5	0.2	1.4	-0.1	0.5	0.2	1.4	0.7	0.7	1.5	0.5	0.8	2.1	-0.5	1.8	0.6	0.7	0.4	0.6	0.0
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.7	-0.2	-0.7	-0.3	-0.3	-0.5	-0.2	-0.2	-0.2	0.2	-0.3	-0.3	-0.3	-0.9	-0.7	-0.3	-0.4	-0.1	-0.1	0.2
Neuroticism	0.1	0.2	1.3	-0.4	0.5	-0.3	0.4	0.1	0.1	0.0	-0.4	-0.5	0.2	-0.2	-0.0	0.1	1.1	0.2	0.5	-0.3	0.1	0.3
Average weekly spirits intake	0.1	0.1	1.1	-0.3	-0.0	-0.1	0.0	-0.0	-0.1	-0.1	-0.2	-1.1	-0.0	0.3	0.2	0.4	-0.1	-0.1	0.0	-0.3	-0.4	-0.5
Frequency of depressed mood in last 2 weeks	0.1	0.2	1.0	-0.4	0.1	-0.3	0.1	-0.4	0.3	-0.4	-0.7	-1.0	-0.3	-0.3	-0.3	-0.4	0.1	-0.1	0.1	-0.4	-0.1	-0.5
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.3	0.2	-0.3	-0.2	-0.1	-0.1	0.2	-0.4	-0.5	-0.1	-0.3	-0.3	-0.5	-0.4	-0.1	-0.1	-0.2	-0.0	0.0	-0.2
Angina	0.1	0.2	0.8	0.0	-0.1	0.3	0.4	-0.4	0.9	-0.3	-0.4	-0.7	0.1	0.0	0.3	-0.8	-0.6	0.0	-0.0	0.4	-0.0	-0.3
Severe depression (siblings)	0.1	0.1	0.3	-0.1	0.1	0.3	0.2	0.3	0.3	0.2	0.5	-0.2	0.6	0.4	0.5	0.2	0.2	0.4	0.2	0.2	0.1	0.3
Current tobacco smoking	0.1	0.2	1.1	0.4	-0.1	-0.1	0.0	0.0	-0.4	-0.4	-0.1	-0.9	-0.3	-0.6	-1.1	0.8	-0.4	-0.2	-0.2	-0.2	0.0	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.5	-0.4	0.0	-0.2	0.1	-0.4	0.5	-0.4	-0.6	-0.6	-0.2	-0.4	0.0	-0.7	0.3	-0.1	-0.0	-0.3	-0.2	-0.2
Taking other prescription medications	0.1	0.1	1.0	0.1	0.1	0.4	0.2	-0.5	1.0	-0.2	-0.1	-0.4	0.1	-0.3	0.3	-0.6	-0.3	0.1	-0.1	0.0	0.0	-0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	-0.4	0.2	-0.3	-0.2	-0.1	-0.6	0.0	-0.0	0.4	-0.1	0.1	0.3	-0.2	0.2	-0.2	-0.1	0.2	-0.3	0.2
Body mass index (BMI)	0.1	0.4	2.2	-0.5	0.1	0.5	0.3	-0.5	1.0	0.1	-0.4	-1.5	0.2	0.6	1.1	-1.1	-0.7	0.1	0.4	0.0	-0.2	-0.7
Medication: Simvastatin	0.1	0.2	1.5	0.3	0.0	0.4	0.3	-0.4	1.2	0.1	0.2	0.4	0.2	-0.0	0.7	-0.8	-0.2	0.2	0.1	0.1	0.3	-0.1
Worrier / anxious feelings	0.1	0.2	1.3	0.3	0.5	-0.0	0.5	0.4	0.4	-0.0	0.1	0.6	0.4	-0.3	-0.2	0.4	1.2	0.3	0.2	0.5	0.4	0.7
Happiness	0.1	0.2	0.6	-0.2	-0.0	-0.3	0.2	-0.3	0.5	-0.6	-0.8	-0.7	-0.3	-0.6	-0.7	-0.3	0.1	-0.1	-0.1	-0.1	-0.1	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.4	0.3	-0.2	-0.1	0.2	-0.1	0.6	0.1	-0.6	0.5	-0.1	-0.1	0.1	-0.5	-0.0	0.1	0.2	-0.2	0.2	0.1
Tense / ‘highly strung’	0.1	0.1	1.2	-0.0	0.3	-0.2	0.5	0.3	0.3	-0.2	-0.2	-0.3	0.2	-0.2	-0.2	0.6	1.1	0.2	0.2	-0.0	0.1	0.4
Hair/balding pattern: Pattern 4	0.1	0.4	1.9	-1.4	0.4	-0.3	-0.6	0.2	-0.5	-0.4	0.8	-0.8	0.3	0.3	0.9	0.4	0.3	0.1	-0.5	-0.4	-0.8	-0.5
Headache pain in last month	0.1	0.2	0.6	-0.3	-0.2	-0.3	-0.1	0.2	-0.8	0.4	0.0	0.6	-0.1	-0.5	-0.7	0.2	-0.1	-0.0	0.1	-0.5	0.3	0.7
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.9	-0.1	-0.2	-0.4	-0.5	0.0	-0.9	-0.8	-0.1	-0.3	-0.3	-0.5	-1.0	0.5	0.2	-0.4	-0.6	0.4	-0.5	0.1
High blood pressure (siblings)	0.1	0.1	0.5	-0.4	0.0	0.1	0.1	0.2	0.2	0.4	-0.4	-0.3	0.3	0.7	0.4	-0.4	-0.4	0.2	0.4	-0.0	-0.1	-0.2
Health satisfaction	0.1	0.1	0.2	-0.5	0.4	-0.1	0.3	-0.1	0.1	0.1	0.2	-0.0	0.2	-0.0	0.2	-0.3	0.3	0.1	0.1	0.4	0.1	0.5
Shortness of breath walking on level ground	0.1	0.1	0.9	0.1	-0.2	0.3	0.4	-0.1	0.9	0.1	-0.2	-0.7	0.0	0.1	0.3	-0.2	-0.2	0.2	0.3	-0.0	0.2	-0.4
Migraine (self-reported)	0.1	0.1	0.3	0.4	-0.3	0.2	0.1	0.4	0.3	0.2	-0.2	0.3	0.0	-0.1	-0.6	0.2	-0.3	0.2	0.2	-0.2	0.4	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.7	0.5	0.5	0.5	0.2	0.3	0.2	0.1	0.8	-0.1	0.4	0.1	0.2	0.9	0.2	0.4	0.0	0.5	0.1	0.0
Breast cancer (self-reported)	0.1	0.1	0.5	0.2	0.4	0.1	0.5	0.4	0.2	0.0	-0.2	-0.1	0.1	0.1	-0.2	0.6	0.7	0.4	0.4	0.1	0.2	0.2
Smoking status: Current	0.1	0.2	1.0	0.8	0.3	0.2	0.4	0.4	0.1	0.1	0.2	-0.2	0.1	-0.2	-0.6	1.0	0.2	0.2	0.2	0.2	0.5	0.3
Hearing aid user	0.1	0.1	0.5	-0.1	-0.2	-0.6	-0.2	-0.1	-0.7	0.0	0.0	0.7	-0.3	-0.5	-0.5	-0.1	0.2	-0.3	-0.3	-0.2	0.1	0.5
Mother’s age at death	0.1	0.2	0.5	-0.4	-0.2	-0.7	-0.3	-0.5	0.1	-0.3	-0.5	0.3	-0.5	-0.5	0.0	-0.7	0.2	-0.4	-0.1	-0.4	-0.1	-0.4
Medication: Bendroflumethiazide	0.1	0.1	0.7	-0.1	0.4	0.7	-0.0	-0.2	0.6	-0.1	0.0	0.1	0.2	-0.0	0.5	-0.8	0.1	0.0	-0.2	0.1	-0.2	-0.3
Medication: Paracetamol	0.1	0.2	1.4	-0.1	0.0	0.5	0.5	-0.0	1.2	0.2	-0.4	-0.5	0.2	-0.1	0.4	-0.5	-0.2	0.4	0.5	-0.3	0.3	-0.2
Diastolic blood pressure, automated reading	0.1	0.3	1.7	0.0	0.4	0.6	0.1	0.2	0.9	-0.0	0.0	-1.3	0.3	0.7	0.7	0.2	-0.0	0.3	0.2	-0.1	-0.2	-0.9
Ever depressed for a whole week	0.1	0.1	0.4	-0.3	0.1	0.2	0.1	0.2	0.5	0.1	0.2	-0.3	0.3	0.4	0.6	0.2	0.1	0.3	0.2	-0.1	-0.0	-0.4
Blood Eosinophil Count	0.0	0.4	1.8	-0.6	0.0	0.4	0.0	0.1	1.1	-0.1	-0.0	-1.2	0.2	0.5	1.3	-0.4	-0.2	0.3	0.1	-0.4	-0.2	-1.2
Blood Platelet Count	0.0	0.4	2.6	0.2	0.1	-0.8	0.0	0.3	-0.2	-0.2	0.1	1.6	-0.0	-0.7	-1.0	-0.1	0.6	-0.1	-0.1	0.5	0.8	1.0
Allergy or Eczema	0.0	0.1	0.3	-0.4	-0.2	-0.2	-0.2	-0.4	-0.0	-0.4	0.1	-0.0	0.1	-0.2	0.1	-0.5	-0.3	-0.2	-0.4	0.3	-0.4	0.1
Fractured/broken bones in last 5 years	0.0	0.0	0.1	-0.2	0.1	0.0	-0.2	0.2	-0.3	0.1	0.2	0.0	-0.1	0.1	-0.1	0.2	-0.2	0.0	-0.1	-0.3	-0.1	0.0

Hub : Genes

UQCC

Models

Trait associations