Best TWAS P=8.51e-12 · Best GWAS P=3.43e-14 conditioned to 0.294
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | U91328.21 | 0.18 | 0.00 | lasso | 11 | 0.02 | 0.0353 | -0.52 | 5.7 | 1.2e-08 | -0.31 | 0.10 | 0.48 | TRUE |
| 2 | GTEx | Artery Tibial | TRIM38 | 0.08 | 0.00 | lasso | 9 | 0.00 | 0.3730 | 4.13 | 5.1 | 2.8e-07 | -0.21 | 0.18 | 0.42 | FALSE |
| 3 | GTEx | Artery Tibial | U91328.21 | 0.09 | 0.01 | lasso | 8 | 0.01 | 0.0300 | 2.87 | 6.8 | 8.5e-12 | -0.51 | 0.14 | 0.57 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | TRIM38 | 0.09 | 0.00 | enet | 21 | 0.02 | 0.0063 | 1.66 | 5.8 | 7.3e-09 | -0.52 | 0.13 | 0.60 | TRUE |