[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr6:33,745,071-36,804,187

Best TWAS P=7.8e-27 · Best GWAS P=1.1e-23 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
25	NTR	Blood	ZNF76	0.01	0.00	blup	424	0.00	3.8e-02	-8.0	10.7	7.8e-27	-0.08	0.08	0.68	TRUE
39	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RPL10A	0.07	0.07	lasso	2	0.06	9.9e-08	-8.7	-8.8	1.0e-18	-0.04	0.86	0.14	TRUE
20	GTEx	Testis	ZNF76	0.15	0.14	enet	8	0.12	4.4e-06	-7.1	7.9	3.6e-15	0.03	0.53	0.44	TRUE
29	ROSMAP	Brain Pre-frontal Cortex	C6orf106	0.30	0.26	bslmm	372	0.33	9.3e-44	4.5	7.4	1.5e-13	0.06	1.00	0.00	TRUE
3	GTEx	Adipose Subcutaneous	RPL10A	0.06	0.02	enet	27	0.03	2.6e-03	-7.5	-7.3	2.8e-13	-0.08	0.21	0.38	TRUE
53	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZNF76	0.03	0.02	lasso	3	0.02	3.5e-03	-6.6	7.2	8.2e-13	-0.01	0.16	0.49	TRUE
56	The Cancer Genome Atlas	Thyroid Carcinoma	SCUBE3	0.03	0.01	blup	62	0.03	8.9e-04	-8.0	6.8	8.7e-12	-0.03	0.05	0.64	TRUE
45	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf126	0.03	0.00	enet	8	0.01	1.8e-02	4.9	5.5	3.2e-08	0.02	0.01	0.41	TRUE
38	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C6orf106	0.04	0.01	blup	68	0.01	2.4e-02	4.5	5.4	7.8e-08	0.11	0.03	0.20	TRUE
12	GTEx	Heart Atrial Appendage	MAPK13	0.12	0.00	lasso	5	0.00	3.1e-01	-6.0	5.3	1.1e-07	0.02	0.06	0.20	TRUE
33	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RPL10A	0.03	0.00	blup	54	0.02	6.0e-03	-9.5	-10.6	3.8e-26	0.01	0.01	0.80	FALSE
1	CommonMind	Brain Pre-frontal Cortex	FANCE	0.03	0.02	bslmm	420	0.01	1.7e-02	-9.4	-10.4	1.7e-25	0.01	0.24	0.37	FALSE
48	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TCP11	0.03	0.03	blup	49	0.03	3.5e-04	-9.7	-10.2	1.5e-24	-0.03	0.01	0.97	FALSE
35	The Cancer Genome Atlas	Breast Invasive Carcinoma	TCP11	0.03	0.03	blup	49	0.04	6.6e-08	-8.7	-10.0	1.1e-23	0.01	0.02	0.98	FALSE
57	The Cancer Genome Atlas	Thyroid Carcinoma	TCP11	0.03	0.02	blup	49	0.02	1.6e-03	-9.4	-9.9	3.8e-23	-0.05	0.02	0.77	FALSE
40	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TCP11	0.03	0.02	blup	49	0.02	1.7e-03	-7.6	-9.8	1.1e-22	-0.03	0.06	0.84	FALSE
43	The Cancer Genome Atlas	Brain Lower Grade Glioma	TCP11	0.05	0.04	blup	49	0.06	1.3e-07	-9.7	-9.8	1.3e-22	-0.03	0.01	0.99	FALSE
50	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	TCP11	0.08	0.11	lasso	2	0.11	3.4e-05	-9.4	-9.5	1.7e-21	-0.02	0.01	0.95	FALSE
49	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TCP11	0.05	0.07	lasso	2	0.07	1.9e-05	-9.4	-9.4	3.4e-21	-0.02	0.02	0.96	FALSE
8	GTEx	Colon Transverse	RPL10A	0.12	0.05	lasso	4	0.05	2.5e-03	-8.7	-9.4	8.0e-21	-0.04	0.20	0.32	FALSE
47	The Cancer Genome Atlas	Lung Adenocarcinoma	RPL10A	0.02	0.02	lasso	2	0.02	3.8e-03	-9.2	-9.2	3.7e-20	-0.02	0.07	0.18	FALSE
55	The Cancer Genome Atlas	Thyroid Carcinoma	RPL10A	0.05	0.07	enet	4	0.04	1.2e-04	-8.8	-9.1	9.0e-20	-0.05	0.69	0.14	FALSE
37	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TCP11	0.03	0.00	blup	49	0.01	8.8e-03	-9.7	-9.0	2.0e-19	0.02	0.01	0.89	FALSE
4	GTEx	Artery Aorta	RPL10A	0.20	0.12	lasso	5	0.11	8.8e-07	-8.8	-9.0	3.0e-19	-0.05	0.93	0.03	FALSE
11	GTEx	Esophagus Muscularis	RPL10A	0.31	0.19	lasso	5	0.18	4.6e-11	-8.8	-8.8	1.4e-18	-0.03	1.00	0.00	FALSE
52	The Cancer Genome Atlas	Prostate Adenocarcinoma	TCP11	0.03	0.03	lasso	3	0.04	3.8e-05	-8.7	-8.7	2.3e-18	0.04	0.02	0.93	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	TEAD3	0.15	0.06	lasso	5	0.08	2.5e-05	-7.6	-8.6	6.6e-18	-0.09	0.58	0.27	FALSE
36	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	TCP11	0.07	0.01	enet	8	0.01	8.2e-02	-9.5	-8.5	1.3e-17	-0.02	0.01	0.85	FALSE
9	GTEx	Esophagus Mucosa	RPL10A	0.14	0.10	enet	17	0.09	2.1e-06	-8.7	-8.4	2.9e-17	-0.09	0.93	0.02	FALSE
26	ROSMAP	Brain Pre-frontal Cortex	DEF6	0.04	0.02	bslmm	421	0.02	1.8e-03	-9.3	8.4	3.1e-17	-0.09	0.25	0.70	FALSE
17	GTEx	Nerve Tibial	RPL10A	0.14	0.12	lasso	3	0.12	9.7e-09	-8.8	-8.4	3.6e-17	-0.03	0.99	0.00	FALSE
6	GTEx	Artery Tibial	RPL10A	0.11	0.08	lasso	2	0.09	1.5e-07	-8.7	-8.4	6.2e-17	-0.07	0.99	0.01	FALSE
23	METSIM	Adipose	RPL10A	0.18	0.13	lasso	15	0.13	3.4e-19	-8.8	-8.3	1.1e-16	-0.03	1.00	0.00	FALSE
54	The Cancer Genome Atlas	Thyroid Carcinoma	C6orf106	0.08	0.00	enet	15	0.05	2.5e-05	-5.9	8.2	2.1e-16	0.00	0.01	0.74	FALSE
51	The Cancer Genome Atlas	Prostate Adenocarcinoma	RPL10A	0.09	0.03	enet	19	0.07	1.1e-07	-8.8	-8.2	2.8e-16	-0.01	0.75	0.21	FALSE
31	YFS	Blood	RPL10A	0.24	0.11	lasso	11	0.13	4.4e-39	-8.8	-7.9	3.8e-15	-0.02	1.00	0.00	FALSE
46	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf81	0.05	0.00	blup	43	0.02	8.9e-04	5.7	-7.8	6.2e-15	0.02	0.02	0.34	FALSE
13	GTEx	Lung	RPL10A	0.21	0.09	enet	53	0.09	1.2e-07	-8.8	-7.7	1.1e-14	-0.03	0.92	0.04	FALSE
32	YFS	Blood	ZNF76	0.05	0.08	lasso	4	0.07	6.7e-23	-7.8	7.7	1.2e-14	-0.08	1.00	0.00	FALSE
7	GTEx	Cells Transformed fibroblasts	TEAD3	0.36	0.29	enet	27	0.32	8.4e-25	4.6	-7.6	3.1e-14	-0.01	1.00	0.00	FALSE
15	GTEx	Nerve Tibial	DEF6	0.15	0.00	lasso	8	0.00	1.6e-01	-7.8	7.6	3.7e-14	0.00	0.17	0.07	FALSE
27	ROSMAP	Brain Pre-frontal Cortex	ZNF76	0.04	0.00	blup	424	0.02	2.1e-03	-7.8	7.6	3.8e-14	-0.08	0.36	0.34	FALSE
19	GTEx	Skin Sun Exposed Lower leg	C6orf106	0.09	0.04	enet	25	0.02	4.6e-03	-5.6	7.3	2.6e-13	0.08	0.38	0.02	FALSE
14	GTEx	Muscle Skeletal	RPL10A	0.10	0.05	enet	17	0.04	3.9e-05	-8.7	-7.2	5.7e-13	-0.05	0.58	0.22	FALSE
21	GTEx	Thyroid	RPL10A	0.16	0.09	lasso	11	0.07	8.9e-06	-7.0	-7.2	5.8e-13	-0.11	0.88	0.02	FALSE
28	ROSMAP	Brain Pre-frontal Cortex	PACSIN1	0.09	0.00	blup	359	0.02	4.5e-04	4.6	6.8	1.4e-11	0.31	0.18	0.07	FALSE
34	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPL10A	0.03	0.00	blup	55	0.01	1.4e-03	-8.8	-6.7	1.5e-11	-0.04	0.05	0.09	FALSE
44	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ZNF76	0.08	0.05	lasso	10	0.07	4.9e-04	-8.0	-6.7	1.9e-11	-0.01	0.03	0.58	FALSE
22	GTEx	Whole Blood	DEF6	0.14	0.05	lasso	4	0.03	9.9e-04	-7.4	6.7	2.0e-11	-0.07	0.82	0.06	FALSE
5	GTEx	Artery Tibial	C6orf106	0.07	0.02	lasso	4	0.02	8.8e-03	-6.2	6.6	4.4e-11	-0.07	0.09	0.14	FALSE
42	The Cancer Genome Atlas	Brain Lower Grade Glioma	DEF6	0.04	0.01	blup	50	0.03	6.2e-04	-7.8	6.1	1.0e-09	-0.13	0.06	0.73	FALSE
30	ROSMAP	Brain Pre-frontal Cortex	RPL10A	0.30	0.18	bslmm	409	0.19	2.6e-24	-8.7	-6.0	1.8e-09	0.09	1.00	0.00	FALSE
16	GTEx	Nerve Tibial	C6orf106	0.11	0.07	enet	17	0.07	1.3e-05	4.2	6.0	1.9e-09	0.12	0.71	0.02	FALSE
2	CommonMind	Brain Pre-frontal Cortex	RPL10A	0.21	0.09	enet	30	0.11	2.6e-13	-8.7	-6.0	2.7e-09	-0.01	0.90	0.10	FALSE
41	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PPARD	0.07	0.06	lasso	3	0.04	2.5e-03	-5.2	-5.5	4.7e-08	0.10	0.14	0.31	FALSE
24	NTR	Blood	C6orf106	0.03	0.02	lasso	6	0.02	7.2e-07	4.5	5.4	6.4e-08	0.09	1.00	0.00	FALSE
10	GTEx	Esophagus Muscularis	TAF11	0.13	0.02	lasso	6	0.00	1.6e-01	-4.8	5.3	8.9e-08	-0.03	0.06	0.14	FALSE