TWAS
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Models
Genes
Traits
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Traits
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Forced expiratory volume in 1-second (FEV1), Best measure
:
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chr8:8,092,025-9,669,775
Best TWAS P=2.94e-08 · Best GWAS P=1.34e-07 conditioned to 0.0251
8M
8.2M
8.4M
8.6M
8.8M
9M
9.2M
9.4M
9.6M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
ERI1
0.05
0.00
enet
10
0.00
0.54600
-3.1
5.5
2.9e-08
0.64
0.21
0.34
TRUE
2
GTEx
Nerve Tibial
ERI1
0.07
0.01
enet
16
0.01
0.04210
4.0
5.3
9.8e-08
0.69
0.22
0.37
FALSE
3
NTR
Blood
MFHAS1
0.02
0.01
blup
759
0.01
0.00029
-4.9
-5.3
1.5e-07
-0.72
0.08
0.92
FALSE