Best TWAS P=1.26e-20 · Best GWAS P=1.81e-24 conditioned to 0.000266
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | CAMK1D | 0.28 | 0.24 | enet | 25 | 0.24 | 2.3e-18 | -7.6 | -7.5 | 7.7e-14 | 0.51 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Whole Blood | CAMK1D | 0.14 | 0.01 | enet | 26 | 0.04 | 2.5e-04 | -7.6 | -7.5 | 5.5e-14 | 0.63 | 0.24 | 0.68 | FALSE |
| 3 | NTR | Blood | CAMK1D | 0.10 | 0.09 | bslmm | 900 | 0.08 | 4.4e-25 | -7.6 | -8.0 | 1.0e-15 | 0.59 | 1.00 | 0.00 | FALSE |
| 4 | NTR | Blood | CDC123 | 0.06 | 0.04 | bslmm | 537 | 0.04 | 4.7e-14 | -10.2 | -9.0 | 1.7e-19 | 0.91 | 0.00 | 1.00 | TRUE |
| 5 | YFS | Blood | CAMK1D | 0.27 | 0.23 | bslmm | 875 | 0.26 | 7.7e-86 | -7.6 | -8.1 | 5.9e-16 | 0.63 | 1.00 | 0.00 | FALSE |
| 6 | YFS | Blood | CDC123 | 0.08 | 0.03 | enet | 35 | 0.06 | 9.6e-19 | -7.6 | -7.4 | 1.7e-13 | 0.65 | 0.48 | 0.52 | FALSE |
| 7 | YFS | Blood | NUDT5 | 0.13 | 0.12 | enet | 40 | 0.13 | 1.1e-41 | -7.6 | -9.3 | 1.3e-20 | 0.71 | 1.00 | 0.00 | TRUE |
| 8 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CDC123 | 0.26 | 0.07 | lasso | 4 | 0.07 | 1.4e-03 | -7.5 | 8.6 | 5.5e-18 | -0.65 | 0.11 | 0.15 | FALSE |
| 9 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | NUDT5 | 0.13 | -0.01 | blup | 55 | 0.01 | 1.1e-01 | -4.6 | -7.8 | 4.4e-15 | 0.53 | 0.02 | 0.14 | FALSE |
| 10 | The Cancer Genome Atlas | Soft Tissue Sarcoma | CDC123 | 0.08 | 0.00 | blup | 64 | 0.03 | 4.0e-03 | -2.3 | -8.1 | 5.5e-16 | 0.64 | 0.01 | 0.15 | FALSE |
| 11 | The Cancer Genome Atlas | Soft Tissue Sarcoma | NUDT5 | 0.08 | 0.07 | enet | 8 | 0.07 | 8.2e-05 | -3.4 | -7.3 | 2.0e-13 | 0.51 | 0.83 | 0.05 | FALSE |