TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
:
←
→
chr10:30,435,876-32,016,090
Best TWAS P=1.3e-08 · Best GWAS P=6.81e-08 conditioned to 0.0486
30.4M
30.6M
30.8M
31M
31.2M
31.4M
31.6M
31.8M
32M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
ZNF438
0.03
0.00
blup
123
0.02
1.8e-05
4.5
5.7
1.3e-08
0.70
0.08
0.79
TRUE
5
The Cancer Genome Atlas
Lung Adenocarcinoma
ZNF438
0.07
0.03
lasso
5
0.04
1.9e-05
5.4
5.7
1.3e-08
0.89
0.02
0.98
FALSE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
ZNF438
0.09
0.03
enet
10
0.03
7.1e-05
4.5
5.7
1.4e-08
0.82
0.02
0.96
FALSE
3
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
ZNF438
0.10
0.04
lasso
5
0.04
5.9e-05
5.3
5.6
2.1e-08
0.88
0.01
0.96
FALSE
1
YFS
Blood
ZNF438
0.02
0.00
bslmm
501
0.01
3.4e-04
5.4
-5.2
1.6e-07
-0.74
0.02
0.96
FALSE