Best TWAS P=1.3e-08 · Best GWAS P=6.81e-08 conditioned to 0.0486
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | ZNF438 | 0.02 | 0.00 | bslmm | 501 | 0.01 | 3.4e-04 | 5.4 | -5.2 | 1.6e-07 | -0.74 | 0.02 | 0.96 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ZNF438 | 0.03 | 0.00 | blup | 123 | 0.02 | 1.8e-05 | 4.5 | 5.7 | 1.3e-08 | 0.70 | 0.08 | 0.79 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ZNF438 | 0.10 | 0.04 | lasso | 5 | 0.04 | 5.9e-05 | 5.3 | 5.6 | 2.1e-08 | 0.88 | 0.01 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF438 | 0.09 | 0.03 | enet | 10 | 0.03 | 7.1e-05 | 4.5 | 5.7 | 1.4e-08 | 0.82 | 0.02 | 0.96 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF438 | 0.07 | 0.03 | lasso | 5 | 0.04 | 1.9e-05 | 5.4 | 5.7 | 1.3e-08 | 0.89 | 0.02 | 0.98 | FALSE |