Best TWAS P=1.97e-09 · Best GWAS P=2.07e-09 conditioned to 0.0446
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | NRBF2 | 0.06 | 0.01 | lasso | 3 | 0.00 | 4.0e-01 | -5.5 | 5.5 | 3.8e-08 | -0.67 | 0.05 | 0.46 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | ADO | 0.06 | 0.04 | lasso | 2 | 0.06 | 3.1e-08 | -4.0 | 5.5 | 3.1e-08 | -0.83 | 0.03 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ADO | 0.03 | 0.02 | blup | 53 | 0.03 | 1.8e-06 | 4.8 | 6.0 | 2.0e-09 | -0.80 | 0.04 | 0.96 | TRUE |
| 4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | ADO | 0.06 | 0.04 | blup | 55 | 0.01 | 1.4e-01 | -4.0 | 5.5 | 3.2e-08 | -0.87 | 0.02 | 0.56 | FALSE |