[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr11:65,594,820-69,476,279

Best TWAS P=1.52e-24 · Best GWAS P=1.03e-22 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Esophagus Muscularis	RAD9A	0.25	0.26	lasso	2	0.26	6.2e-16	-9.8	-10.2	1.5e-24	0.99	0.00	1.00	TRUE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CCDC87	0.03	0.02	blup	34	0.02	2.0e-03	5.2	6.2	4.7e-10	-0.13	0.01	0.73	TRUE
7	GTEx	Esophagus Muscularis	IGHMBP2	0.12	0.06	enet	17	0.06	9.4e-05	4.3	6.0	2.0e-09	0.05	0.60	0.31	TRUE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SAPS3	0.04	0.02	blup	84	0.04	2.5e-05	-4.1	5.8	8.2e-09	0.00	0.19	0.80	TRUE
2	GTEx	Artery Tibial	RAD9A	0.39	0.26	lasso	2	0.24	3.5e-19	-9.8	-9.8	1.2e-22	1.00	0.00	1.00	FALSE
12	GTEx	Testis	RAD9A	0.72	0.50	lasso	4	0.49	1.1e-24	-9.8	-9.8	1.6e-22	1.00	0.00	1.00	FALSE
11	GTEx	Nerve Tibial	RAD9A	0.53	0.24	lasso	10	0.23	5.6e-16	-9.8	-9.5	2.0e-21	0.99	0.00	1.00	FALSE
1	GTEx	Adipose Subcutaneous	RAD9A	0.43	0.22	lasso	6	0.23	7.1e-19	-9.8	-9.4	6.7e-21	0.97	0.00	1.00	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	RAD9A	0.34	0.17	enet	21	0.20	1.1e-25	-9.8	-9.2	5.7e-20	0.89	0.00	1.00	FALSE
4	GTEx	Cells Transformed fibroblasts	RAD9A	0.24	0.16	lasso	3	0.16	3.6e-12	-9.8	-9.1	7.7e-20	0.92	0.00	1.00	FALSE
5	GTEx	Colon Transverse	RAD9A	0.40	0.16	lasso	8	0.16	7.2e-08	-9.8	-8.6	1.2e-17	0.88	0.00	1.00	FALSE
10	GTEx	Muscle Skeletal	RAD9A	0.12	0.02	lasso	4	0.03	4.2e-04	-9.8	-7.5	4.2e-14	0.83	0.00	0.99	FALSE
16	YFS	Blood	RAD9A	0.08	0.02	lasso	7	0.04	5.4e-12	-9.8	-7.5	4.2e-14	0.78	0.00	1.00	FALSE
13	GTEx	Thyroid	RAD9A	0.27	0.07	lasso	6	0.20	1.8e-15	-9.8	-7.4	1.2e-13	0.70	0.00	1.00	FALSE
6	GTEx	Esophagus Muscularis	TCIRG1	0.10	0.09	lasso	2	0.06	8.7e-05	-4.4	5.8	5.5e-09	-0.43	0.20	0.07	FALSE
9	GTEx	Esophagus Muscularis	MRGPRF	0.09	0.01	lasso	3	0.01	1.3e-01	-4.9	5.8	7.7e-09	0.02	0.03	0.81	FALSE
14	NTR	Blood	MRPL21	0.06	0.07	enet	19	0.07	7.0e-23	4.4	-5.4	7.1e-08	-0.03	1.00	0.00	FALSE
3	GTEx	Brain Cerebellar Hemisphere	ZDHHC24	0.22	0.11	enet	15	0.16	8.2e-05	4.7	-5.1	2.9e-07	0.08	0.07	0.67	FALSE