TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
:
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chr15:98,944,630-101,209,341
Best TWAS P=1.04e-09 · Best GWAS P=2.25e-11 conditioned to 7.25e-08
99M
99.5M
100M
100.5M
101M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
6
The Cancer Genome Atlas
Thyroid Carcinoma
SYNM
0.06
0.04
blup
17
0.03
2.7e-04
-5.0
6.1
1.0e-09
0.09
0.00
0.92
TRUE
2
GTEx
Adipose Visceral Omentum
CTD-3076O17.1
0.21
0.00
lasso
6
0.00
6.2e-01
-3.8
-5.4
6.5e-08
-0.15
0.10
0.20
TRUE
3
GTEx
Brain Cerebellum
SYNM
0.19
0.08
enet
10
0.08
2.7e-03
4.7
5.8
7.9e-09
0.06
0.24
0.11
FALSE
4
YFS
Blood
LRRC28
0.18
0.06
enet
41
0.13
7.4e-40
3.9
5.6
2.3e-08
0.01
0.39
0.47
FALSE
5
The Cancer Genome Atlas
Cervical Squamous Cell Carcinoma
SYNM
0.12
0.08
blup
17
0.07
3.2e-04
-5.0
5.5
4.8e-08
0.09
0.00
0.97
FALSE
1
GTEx
Adipose Subcutaneous
SYNM
0.12
0.09
enet
10
0.10
2.1e-08
5.3
5.2
1.8e-07
0.05
0.70
0.30
FALSE