Best TWAS P=1.04e-09 · Best GWAS P=2.25e-11 conditioned to 7.25e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | SYNM | 0.12 | 0.09 | enet | 10 | 0.10 | 2.1e-08 | 5.3 | 5.2 | 1.8e-07 | 0.05 | 0.70 | 0.30 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | CTD-3076O17.1 | 0.21 | 0.00 | lasso | 6 | 0.00 | 6.2e-01 | -3.8 | -5.4 | 6.5e-08 | -0.15 | 0.10 | 0.20 | TRUE |
| 3 | GTEx | Brain Cerebellum | SYNM | 0.19 | 0.08 | enet | 10 | 0.08 | 2.7e-03 | 4.7 | 5.8 | 7.9e-09 | 0.06 | 0.24 | 0.11 | FALSE |
| 4 | YFS | Blood | LRRC28 | 0.18 | 0.06 | enet | 41 | 0.13 | 7.4e-40 | 3.9 | 5.6 | 2.3e-08 | 0.01 | 0.39 | 0.47 | FALSE |
| 5 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | SYNM | 0.12 | 0.08 | blup | 17 | 0.07 | 3.2e-04 | -5.0 | 5.5 | 4.8e-08 | 0.09 | 0.00 | 0.97 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | SYNM | 0.06 | 0.04 | blup | 17 | 0.03 | 2.7e-04 | -5.0 | 6.1 | 1.0e-09 | 0.09 | 0.00 | 0.92 | TRUE |