[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr15:82,250,003-85,883,064

Best TWAS P=1.47e-16 · Best GWAS P=2.24e-29 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ADAMTSL3	0.10	0.04	lasso	4	0.04	8.7e-06	-8.3	-6.1	1.1e-09	0.24	0.24	0.02	FALSE
2	CommonMind	Brain Pre-frontal Cortex	BTBD1	0.07	0.01	bslmm	356	0.04	1.7e-05	-3.6	-5.3	1.3e-07	-0.03	0.69	0.09	FALSE
3	CommonMind	Brain Pre-frontal Cortex	LOC388152	0.14	0.14	enet	20	0.18	6.7e-22	5.5	-5.7	1.6e-08	0.43	1.00	0.00	FALSE
4	GTEx	Adipose Subcutaneous	WHAMM	0.46	0.45	lasso	3	0.47	2.7e-42	-5.5	6.0	1.9e-09	-0.12	0.71	0.29	FALSE
5	GTEx	Adipose Subcutaneous	AC103965.1	0.24	0.14	lasso	6	0.15	2.6e-12	5.4	-6.2	7.7e-10	0.44	1.00	0.00	FALSE
6	GTEx	Adipose Subcutaneous	RP11-182J1.14	0.11	0.11	lasso	9	0.12	8.1e-10	5.3	6.0	1.7e-09	-0.46	1.00	0.00	FALSE
7	GTEx	Adipose Subcutaneous	CSPG4P11	0.19	0.17	lasso	5	0.20	7.9e-16	5.4	-5.8	5.8e-09	0.42	1.00	0.00	FALSE
8	GTEx	Adipose Visceral Omentum	WHAMM	0.22	0.23	lasso	1	0.21	2.2e-11	-5.5	5.5	5.0e-08	-0.13	0.68	0.32	FALSE
9	GTEx	Adipose Visceral Omentum	AC103965.1	0.12	0.13	lasso	5	0.10	1.0e-05	5.4	-5.3	1.0e-07	0.40	0.97	0.01	FALSE
10	GTEx	Adipose Visceral Omentum	RP11-152F13.7	0.14	0.01	enet	12	0.07	1.9e-04	-2.0	-5.2	1.5e-07	0.06	0.14	0.19	FALSE
11	GTEx	Adipose Visceral Omentum	RP11-182J1.14	0.17	0.05	enet	18	0.08	6.9e-05	5.5	5.6	2.4e-08	-0.40	0.75	0.02	FALSE
12	GTEx	Adrenal Gland	AC103965.1	0.09	0.00	enet	5	-0.01	7.7e-01	5.9	-5.7	1.2e-08	0.43	0.09	0.08	FALSE
13	GTEx	Artery Aorta	AC103965.1	0.10	0.12	lasso	3	0.10	3.9e-06	5.5	-5.5	4.8e-08	0.40	0.95	0.02	FALSE
14	GTEx	Artery Aorta	RP11-182J1.16	0.11	0.12	lasso	3	0.11	1.6e-06	5.4	-5.1	2.9e-07	0.39	0.94	0.00	FALSE
15	GTEx	Artery Aorta	CSPG4P11	0.11	0.10	lasso	4	0.08	3.1e-05	5.4	-5.4	5.4e-08	0.40	0.93	0.01	FALSE
16	GTEx	Artery Coronary	CSPG4P11	0.18	0.02	enet	14	0.11	2.0e-04	4.5	-5.2	2.6e-07	0.36	0.08	0.09	FALSE
17	GTEx	Artery Tibial	SCAND2P	0.12	0.05	enet	16	0.08	8.7e-07	-4.0	-6.7	2.7e-11	0.39	0.32	0.54	FALSE
18	GTEx	Artery Tibial	AC103965.1	0.27	0.26	enet	31	0.30	1.8e-23	5.3	-8.3	1.5e-16	0.56	1.00	0.00	TRUE
19	GTEx	Artery Tibial	CSPG4P11	0.16	0.24	lasso	4	0.23	3.0e-18	5.3	-6.8	7.5e-12	0.54	1.00	0.00	FALSE
20	GTEx	Brain Cerebellar Hemisphere	UBE2Q2P1	0.18	0.08	enet	18	0.12	4.2e-04	6.0	5.9	3.0e-09	-0.45	0.18	0.18	FALSE
21	GTEx	Brain Cerebellar Hemisphere	CSPG4P11	0.30	0.21	lasso	3	0.16	7.6e-05	5.7	5.8	5.9e-09	-0.44	0.39	0.08	FALSE
22	GTEx	Brain Cerebellum	AC103965.1	0.13	0.02	enet	21	0.01	2.1e-01	5.5	-8.2	2.2e-16	0.67	0.04	0.72	FALSE
23	GTEx	Brain Cortex	BTBD1	0.33	0.13	lasso	5	0.22	7.9e-07	4.4	-5.5	3.5e-08	0.08	0.20	0.05	FALSE
24	GTEx	Brain Cortex	GOLGA6L4	0.42	0.21	lasso	7	0.28	2.8e-08	-4.5	-6.6	4.9e-11	0.36	0.63	0.06	TRUE
25	GTEx	Brain Cortex	AC103965.1	0.17	0.19	lasso	3	0.16	4.3e-05	5.3	-6.1	1.4e-09	0.46	0.20	0.45	FALSE
26	GTEx	Brain Cortex	RP11-182J1.14	0.24	0.03	enet	14	0.16	3.2e-05	5.9	7.7	1.2e-14	-0.46	0.07	0.22	FALSE
27	GTEx	Brain Frontal Cortex BA9	AC103965.1	0.27	0.17	lasso	7	0.16	6.0e-05	5.3	-5.5	4.6e-08	0.41	0.35	0.07	FALSE
28	GTEx	Brain Hippocampus	GOLGA6L5	0.41	0.05	enet	35	0.15	2.2e-04	-2.9	-5.1	2.9e-07	0.14	0.33	0.04	FALSE
29	GTEx	Brain Hypothalamus	AC103965.1	0.21	0.24	lasso	6	0.21	1.4e-05	5.9	-5.4	7.2e-08	0.42	0.32	0.18	FALSE
30	GTEx	Brain Nucleus accumbens basal ganglia	GOLGA6L4	0.21	0.04	lasso	5	0.09	2.3e-03	-9.4	-6.5	1.1e-10	0.25	0.06	0.06	FALSE
31	GTEx	Brain Nucleus accumbens basal ganglia	AC103965.1	0.29	0.23	enet	21	0.27	6.9e-08	5.9	-5.9	3.7e-09	0.48	0.86	0.08	FALSE
32	GTEx	Brain Putamen basal ganglia	AC103965.1	0.26	0.19	lasso	7	0.22	4.5e-06	5.9	-5.3	1.4e-07	0.39	0.69	0.10	FALSE
33	GTEx	Breast Mammary Tissue	WHAMM	0.18	0.18	enet	10	0.09	1.8e-05	-5.5	5.6	2.1e-08	-0.13	0.62	0.38	FALSE
34	GTEx	Breast Mammary Tissue	AC103965.1	0.13	0.11	lasso	1	0.13	2.9e-07	5.3	-5.3	9.1e-08	0.40	0.89	0.05	TRUE
35	GTEx	Breast Mammary Tissue (Male)	AC103965.1	0.24	0.14	lasso	4	0.11	1.4e-03	5.3	-6.9	6.7e-12	0.53	0.12	0.29	FALSE
36	GTEx	Breast Mammary Tissue (Male)	RN7SL417P	0.20	0.12	lasso	3	0.10	3.1e-03	6.0	6.1	7.8e-10	-0.46	0.06	0.12	FALSE
37	GTEx	Breast Mammary Tissue (Male)	RP11-182J1.14	0.04	-0.01	enet	1	-0.01	5.9e-01	5.9	5.9	4.4e-09	-0.43	0.03	0.08	FALSE
38	GTEx	Breast Mammary Tissue (Male)	CSPG4P11	0.05	0.02	lasso	6	0.03	7.1e-02	5.5	-6.1	1.1e-09	0.44	0.03	0.09	FALSE
39	GTEx	Cells EBV-transformed lymphocytes	RP11-152F13.7	0.46	0.12	lasso	9	0.16	7.4e-06	-3.8	-5.7	1.6e-08	0.10	0.24	0.10	FALSE
40	GTEx	Cells Transformed fibroblasts	SCAND2P	0.29	0.20	enet	39	0.21	6.5e-16	-4.0	-5.7	1.1e-08	0.32	0.98	0.02	FALSE
41	GTEx	Cells Transformed fibroblasts	AC103965.1	0.15	0.09	lasso	7	0.11	1.3e-08	5.4	-6.5	7.5e-11	0.49	0.98	0.01	FALSE
42	GTEx	Colon Sigmoid	RN7SL417P	0.17	0.06	lasso	4	0.12	6.1e-05	5.9	5.9	4.8e-09	-0.46	0.28	0.09	FALSE
43	GTEx	Colon Sigmoid	RP11-182J1.14	0.31	0.29	lasso	9	0.30	2.7e-11	5.9	6.0	2.1e-09	-0.46	1.00	0.00	FALSE
44	GTEx	Colon Transverse	RP11-182J1.14	0.23	0.19	enet	27	0.18	3.9e-09	5.5	6.2	6.5e-10	-0.46	1.00	0.00	FALSE
45	GTEx	Esophagus Gastroesophageal Junction	SCAND2P	0.21	0.11	lasso	3	0.12	3.4e-05	-4.0	-5.4	8.6e-08	0.39	0.18	0.27	FALSE
46	GTEx	Esophagus Gastroesophageal Junction	AC103965.1	0.13	0.14	lasso	4	0.15	3.2e-06	5.9	-6.0	2.0e-09	0.42	0.48	0.06	FALSE
47	GTEx	Esophagus Gastroesophageal Junction	CSPG4P11	0.18	0.06	lasso	2	0.06	3.5e-03	5.7	-6.0	2.4e-09	0.43	0.23	0.04	FALSE
48	GTEx	Esophagus Gastroesophageal Junction	RP11-382A20.2	0.13	0.03	enet	20	0.07	1.1e-03	4.4	7.2	4.7e-13	-0.12	0.11	0.14	TRUE
49	GTEx	Esophagus Mucosa	UBE2Q2P1	0.38	0.26	enet	37	0.28	3.7e-19	5.3	5.8	5.0e-09	-0.38	1.00	0.00	FALSE
50	GTEx	Esophagus Mucosa	AC103965.1	0.20	0.19	enet	47	0.16	8.4e-11	5.3	-6.8	9.9e-12	0.38	1.00	0.00	FALSE
51	GTEx	Esophagus Mucosa	RP11-182J1.16	0.20	0.05	lasso	5	0.10	1.8e-07	5.9	-5.8	7.3e-09	0.42	0.90	0.00	FALSE
52	GTEx	Esophagus Mucosa	CSPG4P11	0.21	0.01	enet	28	0.08	3.7e-06	-3.9	-5.9	4.0e-09	0.46	0.86	0.04	FALSE
53	GTEx	Esophagus Muscularis	AC103965.1	0.18	0.14	enet	16	0.14	7.6e-09	5.7	-6.2	5.0e-10	0.46	1.00	0.00	FALSE
54	GTEx	Esophagus Muscularis	CSPG4P11	0.12	0.16	lasso	5	0.18	4.0e-11	5.4	-5.4	7.8e-08	0.38	1.00	0.00	FALSE
55	GTEx	Heart Atrial Appendage	RP11-182J1.14	0.06	0.05	lasso	3	0.05	3.6e-03	5.9	5.9	4.8e-09	-0.44	0.17	0.24	FALSE
56	GTEx	Heart Left Ventricle	AC103965.1	0.16	0.13	enet	14	0.12	7.0e-07	5.9	-5.2	1.9e-07	0.39	0.98	0.00	FALSE
57	GTEx	Liver	GOLGA6L9	0.15	0.00	lasso	4	-0.01	7.8e-01	6.4	-5.3	9.0e-08	0.09	0.01	0.74	FALSE
58	GTEx	Lung	AC103965.1	0.20	0.14	lasso	4	0.16	1.8e-12	5.3	-5.7	1.6e-08	0.40	1.00	0.00	FALSE
59	GTEx	Nerve Tibial	WHAMM	0.11	0.07	lasso	5	0.04	1.2e-03	-5.5	5.2	2.3e-07	-0.11	0.01	0.94	FALSE
60	GTEx	Nerve Tibial	SCAND2P	0.23	0.11	enet	18	0.13	2.6e-09	-3.8	-5.5	3.1e-08	0.36	0.99	0.01	FALSE
61	GTEx	Nerve Tibial	UBE2Q2P1	0.13	0.01	enet	37	0.04	1.3e-03	5.5	5.5	4.7e-08	-0.30	0.10	0.38	FALSE
62	GTEx	Nerve Tibial	AC103965.1	0.20	0.22	enet	17	0.27	5.1e-19	5.3	-7.5	9.3e-14	0.58	1.00	0.00	FALSE
63	GTEx	Pancreas	AC103965.1	0.29	0.23	lasso	9	0.18	2.8e-08	5.5	-6.4	1.8e-10	0.44	1.00	0.00	FALSE
64	GTEx	Pancreas	RP11-182J1.16	0.08	-0.01	enet	11	-0.01	7.9e-01	-3.9	-6.4	1.4e-10	0.46	0.05	0.16	FALSE
65	GTEx	Pituitary	AC103965.1	0.30	0.16	enet	10	0.24	8.4e-07	5.1	-6.6	3.5e-11	0.45	0.40	0.22	FALSE
66	GTEx	Prostate	RP11-182J1.16	0.24	0.06	enet	27	0.08	6.2e-03	1.0	-7.7	1.5e-14	0.48	0.09	0.10	FALSE
67	GTEx	Prostate	RP11-182J1.14	0.25	0.09	enet	25	0.09	2.9e-03	5.7	6.1	1.1e-09	-0.35	0.19	0.08	FALSE
68	GTEx	Skin Not Sun Exposed Suprapubic	AC103965.1	0.23	0.15	lasso	8	0.19	1.9e-10	5.5	-5.1	2.9e-07	0.34	0.96	0.01	FALSE
69	GTEx	Skin Not Sun Exposed Suprapubic	RP11-182J1.16	0.10	0.01	enet	13	0.04	3.1e-03	1.2	-5.1	3.1e-07	0.36	0.35	0.10	FALSE
70	GTEx	Skin Sun Exposed Lower leg	ZSCAN2	0.08	0.02	enet	13	0.03	1.4e-03	-3.9	5.2	2.0e-07	-0.22	0.29	0.29	TRUE
71	GTEx	Skin Sun Exposed Lower leg	AC103965.1	0.33	0.17	enet	24	0.23	4.8e-19	5.3	-7.0	3.2e-12	0.45	1.00	0.00	FALSE
72	GTEx	Small Intestine Terminal Ileum	RP11-182J1.14	0.26	0.01	enet	27	0.12	1.3e-03	-11.2	8.0	8.7e-16	-0.61	0.02	0.62	FALSE
73	GTEx	Spleen	GOLGA6L4	0.55	0.20	enet	19	0.40	2.6e-11	-4.0	-5.6	2.4e-08	0.40	0.89	0.01	TRUE
74	GTEx	Stomach	AC103965.1	0.14	0.11	lasso	3	0.10	1.1e-05	5.3	-5.7	1.2e-08	0.40	0.84	0.01	FALSE
75	GTEx	Testis	BTBD1	0.06	0.01	enet	8	0.04	1.1e-02	3.9	-6.2	4.4e-10	0.00	0.10	0.37	TRUE
76	GTEx	Testis	AC103965.1	0.07	0.07	lasso	2	0.06	1.6e-03	5.3	-5.2	2.0e-07	0.39	0.52	0.04	FALSE
77	GTEx	Testis	RP11-152F13.7	0.18	0.02	enet	15	0.09	1.3e-04	3.9	-5.2	1.6e-07	0.11	0.12	0.10	FALSE
78	GTEx	Testis	RP11-182J1.14	0.10	0.19	lasso	1	0.17	6.7e-08	5.3	5.3	9.1e-08	-0.40	0.94	0.00	FALSE
79	GTEx	Thyroid	AC103965.1	0.30	0.25	lasso	7	0.25	1.8e-19	5.4	-5.6	2.8e-08	0.42	1.00	0.00	FALSE
80	GTEx	Whole Blood	GOLGA6L4	0.12	0.08	enet	16	0.11	2.1e-10	-3.8	-5.4	7.0e-08	0.40	0.99	0.00	FALSE
81	METSIM	Adipose	WHAMM	0.35	0.30	lasso	2	0.30	4.0e-46	-5.7	5.7	1.0e-08	-0.14	0.33	0.67	TRUE
82	The Cancer Genome Atlas	Breast Invasive Carcinoma	GOLGA6L5	0.04	0.04	enet	5	0.05	4.6e-11	-2.9	-5.6	2.0e-08	0.44	0.12	0.86	FALSE
83	The Cancer Genome Atlas	Esophageal Carcinoma	LOC388152	0.10	0.08	enet	2	0.08	1.8e-03	5.4	-5.4	7.3e-08	0.41	0.00	0.74	FALSE
84	The Cancer Genome Atlas	Glioblastoma Multiforme	BTBD1	0.20	0.06	lasso	2	0.13	9.1e-05	5.6	-5.5	3.0e-08	0.07	0.00	0.96	TRUE
85	The Cancer Genome Atlas	Glioblastoma Multiforme	LOC388152	0.12	0.08	lasso	3	0.08	1.9e-03	5.4	-5.4	6.3e-08	0.40	0.00	0.67	FALSE
86	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ZSCAN2	0.11	0.00	blup	46	0.03	1.2e-04	3.7	6.7	2.0e-11	-0.25	0.01	0.42	TRUE
87	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GOLGA6L5	0.04	0.01	blup	7	0.03	4.9e-04	5.5	-5.8	5.3e-09	0.44	0.00	0.98	FALSE
88	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	WHAMM	0.16	0.18	lasso	3	0.17	3.9e-19	-5.7	5.4	5.4e-08	-0.15	0.33	0.67	FALSE
89	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	WHAMM	0.10	0.11	enet	4	0.11	5.1e-07	-5.7	5.6	2.7e-08	-0.15	0.11	0.88	FALSE
90	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADAMTSL3	0.03	0.02	blup	153	0.01	7.6e-03	5.5	-5.4	6.6e-08	0.43	0.36	0.07	FALSE
91	The Cancer Genome Atlas	Brain Lower Grade Glioma	GOLGA6L5	0.06	0.09	blup	7	0.09	1.5e-10	-3.4	-5.3	1.3e-07	0.40	0.55	0.34	FALSE
92	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	UBE2Q2P1	0.10	0.00	blup	22	0.03	1.9e-02	-4.5	5.1	2.9e-07	-0.34	0.00	0.48	FALSE
93	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	WHAMM	0.14	0.05	enet	11	0.08	1.0e-04	-5.7	6.7	2.4e-11	-0.15	0.01	0.98	FALSE
94	The Cancer Genome Atlas	Lung Adenocarcinoma	GOLGA6L5	0.05	0.04	blup	7	0.05	5.1e-07	-3.4	-5.2	2.3e-07	0.42	0.10	0.62	FALSE
95	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	HOMER2	0.04	0.00	blup	71	0.02	6.6e-03	-5.5	-5.2	2.3e-07	0.10	0.02	0.25	FALSE
96	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LOC388152	0.02	0.03	lasso	1	0.02	1.2e-03	5.4	-5.4	6.7e-08	0.40	0.00	0.92	FALSE
97	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UBE2Q2P1	0.03	0.03	lasso	3	0.02	9.2e-04	5.5	5.8	8.6e-09	-0.43	0.00	0.93	FALSE
98	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LOC388152	0.04	0.05	enet	2	0.05	4.2e-04	5.3	-5.4	7.8e-08	0.41	0.00	0.89	FALSE
99	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LOC388152	0.08	0.11	lasso	3	0.11	2.4e-05	5.4	-5.4	6.3e-08	0.40	0.00	0.97	FALSE
100	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	GOLGA6L5	0.10	0.04	enet	2	0.10	9.9e-05	-3.4	-5.2	1.8e-07	0.41	0.00	0.84	FALSE
101	The Cancer Genome Atlas	Rectum Adenocarcinoma	WHAMM	0.25	0.06	blup	55	0.09	4.2e-03	-5.7	5.8	5.0e-09	-0.12	0.01	0.77	FALSE
102	The Cancer Genome Atlas	Soft Tissue Sarcoma	GOLGA6L5	0.09	0.08	enet	4	0.09	5.2e-06	-3.4	-5.7	1.2e-08	0.45	0.07	0.20	TRUE
103	The Cancer Genome Atlas	Skin Cutaneous Melanoma	WHAMM	0.14	0.17	enet	5	0.13	2.5e-04	-6.2	-6.3	2.5e-10	0.00	0.02	0.57	FALSE
104	The Cancer Genome Atlas	Stomach Adenocarcinoma	GOLGA6L5	0.07	0.01	enet	5	0.06	5.2e-05	-3.4	-5.2	2.3e-07	0.40	0.00	0.96	FALSE