Best TWAS P=3.09e-14 · Best GWAS P=1.3e-11 conditioned to 3e-04
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RAB24 | 0.14 | 0.06 | enet | 14 | 0.09 | 4.2e-11 | 6.2 | 7.1 | 1.0e-12 | 0.71 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | RAB24 | 0.17 | 0.08 | enet | 26 | 0.14 | 1.7e-11 | 6.3 | 6.7 | 1.5e-11 | 0.62 | 0.03 | 0.97 | FALSE |
| 3 | GTEx | Artery Tibial | RAB24 | 0.18 | 0.09 | lasso | 3 | 0.07 | 2.3e-06 | 6.3 | 7.1 | 1.5e-12 | 0.77 | 0.02 | 0.98 | FALSE |
| 4 | GTEx | Heart Atrial Appendage | MXD3 | 0.33 | 0.15 | enet | 24 | 0.16 | 1.5e-07 | 3.5 | 6.7 | 2.5e-11 | 0.29 | 0.81 | 0.03 | FALSE |
| 5 | GTEx | Nerve Tibial | RAB24 | 0.27 | 0.08 | enet | 32 | 0.17 | 6.3e-12 | 4.7 | 7.6 | 3.1e-14 | 0.47 | 0.06 | 0.93 | TRUE |
| 6 | METSIM | Adipose | RAB24 | 0.05 | 0.02 | lasso | 4 | 0.02 | 1.2e-03 | 6.2 | 6.2 | 6.6e-10 | 0.81 | 0.02 | 0.96 | FALSE |
| 7 | The Cancer Genome Atlas | Colon Adenocarcinoma | RAB24 | 0.08 | 0.04 | enet | 7 | 0.06 | 3.4e-04 | -3.3 | 6.5 | 6.4e-11 | 0.54 | 0.02 | 0.65 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | F12 | 0.05 | 0.03 | enet | 4 | 0.03 | 4.0e-04 | 5.7 | 5.7 | 9.0e-09 | 0.25 | 0.01 | 0.87 | FALSE |
| 9 | The Cancer Genome Atlas | Prostate Adenocarcinoma | RAB24 | 0.23 | 0.04 | enet | 19 | 0.06 | 6.5e-07 | 6.2 | 5.4 | 8.8e-08 | 0.60 | 0.00 | 0.98 | FALSE |