Best TWAS P=9.38e-13 · Best GWAS P=6.99e-23 conditioned to 4.77e-12
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | -7.2 | 7.1 | 9.4e-13 | -0.39 | 0.32 | 0.12 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | 6.3 | -6.5 | 6.7e-11 | 0.31 | 0.66 | 0.02 | TRUE |