[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), predicted : ← →

chr5:130,830,617-132,693,330

Best TWAS P=5.27e-12 · Best GWAS P=2.96e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	P4HA2	0.12	0.14	lasso	2	0.11	1.2e-06	5.9	5.9	2.9e-09	1.00	0.01	0.99	FALSE
2	GTEx	Artery Aorta	AC034220.3	0.08	0.06	lasso	3	0.05	1.1e-03	-4.4	5.4	6.9e-08	0.74	0.36	0.46	FALSE
3	GTEx	Artery Aorta	P4HA2-AS1	0.08	0.03	lasso	3	0.01	6.6e-02	5.8	5.8	6.1e-09	0.96	0.02	0.96	FALSE
4	GTEx	Artery Tibial	P4HA2	0.12	0.15	lasso	6	0.14	3.2e-11	5.9	5.8	5.0e-09	0.96	0.01	0.99	FALSE
5	GTEx	Artery Tibial	P4HA2-AS1	0.10	0.09	lasso	4	0.11	1.0e-08	5.8	5.6	1.7e-08	0.93	0.01	0.99	FALSE
6	GTEx	Cells Transformed fibroblasts	SLC22A5	0.32	0.28	lasso	7	0.35	1.6e-27	-4.8	-5.2	2.5e-07	-0.84	0.46	0.54	FALSE
7	GTEx	Esophagus Mucosa	P4HA2	0.23	0.10	lasso	6	0.14	6.1e-10	5.9	6.9	5.3e-12	0.95	0.01	0.99	TRUE
8	GTEx	Esophagus Mucosa	SLC22A5	0.16	0.16	enet	8	0.16	6.3e-11	5.4	-5.4	5.7e-08	-0.95	0.02	0.98	FALSE
9	GTEx	Esophagus Mucosa	P4HA2-AS1	0.09	0.06	lasso	6	0.08	5.4e-06	5.9	6.1	1.1e-09	0.97	0.01	0.99	FALSE
10	GTEx	Heart Atrial Appendage	AC034220.3	0.16	0.09	enet	17	0.18	1.7e-08	-4.3	5.2	2.4e-07	0.77	0.36	0.64	FALSE
11	GTEx	Heart Left Ventricle	AC034220.3	0.25	0.22	lasso	6	0.25	8.6e-14	-4.4	5.3	1.1e-07	0.70	0.90	0.09	FALSE
12	GTEx	Lung	SLC22A5	0.10	0.15	enet	11	0.13	3.4e-10	5.4	-5.2	1.6e-07	-0.93	0.06	0.94	FALSE
13	GTEx	Muscle Skeletal	MIR3936	0.04	0.01	lasso	4	0.00	9.9e-02	-4.6	5.4	7.7e-08	0.82	0.09	0.65	FALSE
14	GTEx	Nerve Tibial	P4HA2	0.19	0.12	enet	26	0.14	6.2e-10	-4.3	5.5	3.7e-08	0.85	0.02	0.98	FALSE
15	GTEx	Nerve Tibial	P4HA2-AS1	0.14	0.05	lasso	8	0.08	3.8e-06	5.6	5.5	4.5e-08	0.88	0.02	0.98	FALSE
16	GTEx	Ovary	AC004041.2	0.21	-0.01	lasso	2	-0.01	7.7e-01	-4.3	5.6	2.4e-08	0.62	0.06	0.28	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	SLC22A5	0.13	0.05	lasso	8	0.05	8.3e-04	-4.2	-5.3	1.5e-07	-0.82	0.16	0.83	FALSE
18	GTEx	Skin Sun Exposed Lower leg	PDLIM4	0.09	0.08	lasso	8	0.09	1.0e-07	5.9	-5.8	8.0e-09	-0.92	0.02	0.98	FALSE
19	GTEx	Skin Sun Exposed Lower leg	SLC22A5	0.25	0.21	lasso	3	0.20	1.4e-16	5.3	-5.2	1.7e-07	-0.90	0.14	0.86	FALSE
20	GTEx	Spleen	SLC22A5	0.26	0.28	lasso	4	0.28	6.6e-08	5.4	5.5	3.4e-08	0.88	0.08	0.81	FALSE
21	GTEx	Testis	P4HA2	0.14	0.13	lasso	5	0.11	1.4e-05	5.9	5.5	2.9e-08	0.98	0.01	0.99	FALSE
22	GTEx	Thyroid	P4HA2	0.08	0.07	enet	9	0.06	3.5e-05	5.9	5.8	8.6e-09	0.95	0.01	0.99	FALSE
23	GTEx	Thyroid	PDLIM4	0.05	0.02	enet	5	0.01	3.1e-02	5.6	-5.7	1.3e-08	-0.88	0.03	0.93	FALSE
24	GTEx	Thyroid	P4HA2-AS1	0.08	0.06	enet	14	0.05	1.6e-04	5.9	5.2	1.6e-07	0.89	0.01	0.99	FALSE
25	GTEx	Whole Blood	SLC22A5	0.09	0.12	lasso	2	0.10	1.7e-09	5.4	-5.4	5.1e-08	-0.90	0.08	0.92	FALSE
26	METSIM	Adipose	PDLIM4	0.05	0.04	lasso	4	0.02	2.8e-04	5.7	-5.8	6.8e-09	-0.83	0.03	0.97	FALSE
27	METSIM	Adipose	SLC22A5	0.05	0.08	lasso	1	0.08	1.0e-11	5.4	-5.4	5.1e-08	-0.90	0.09	0.91	FALSE
28	ROSMAP	Brain Pre-frontal Cortex	SLC22A4	0.03	0.05	lasso	2	0.04	1.2e-05	-5.2	-5.9	4.0e-09	-0.72	0.24	0.72	FALSE
29	YFS	Blood	SLC22A5	0.38	0.36	bslmm	430	0.37	3.0e-128	5.4	-5.8	7.0e-09	-0.88	0.08	0.92	FALSE
30	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SLC22A5	0.05	0.03	blup	93	0.05	1.9e-06	-4.1	-5.1	2.8e-07	-0.74	0.04	0.96	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	P4HA2	0.21	0.35	enet	10	0.35	4.7e-35	5.8	5.5	4.8e-08	0.95	0.01	0.99	FALSE