Best TWAS P=4.72e-17 · Best GWAS P=1.77e-18 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | GPR126 | 0.06 | 0.04 | lasso | 4 | 0.04 | 0.00061 | -8.5 | 8.4 | 4.7e-17 | -0.96 | 0.02 | 0.96 | TRUE |
2 | METSIM | Adipose | GPR126 | 0.05 | 0.01 | blup | 429 | 0.02 | 0.00019 | -3.3 | 6.7 | 2.1e-11 | -0.71 | 0.14 | 0.86 | FALSE |
3 | NTR | Blood | HIVEP2 | 0.02 | 0.01 | blup | 424 | 0.01 | 0.00262 | -3.0 | -5.9 | 3.6e-09 | 0.39 | 0.34 | 0.06 | FALSE |