Best TWAS P=2.72e-09 · Best GWAS P=9.75e-09 conditioned to 0.665
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CFDP1 | 0.08 | 0.04 | lasso | 4 | 0.04 | 1.6e-05 | 5.6 | 5.9 | 2.7e-09 | 0.94 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Adipose Subcutaneous | TMEM170A | 0.11 | 0.00 | lasso | 5 | 0.01 | 6.7e-02 | 5.5 | 5.3 | 1.2e-07 | 0.78 | 0.02 | 0.92 | FALSE |
| 3 | GTEx | Adrenal Gland | TMEM170A | 0.11 | 0.06 | enet | 4 | 0.04 | 1.7e-02 | 5.5 | -5.5 | 3.4e-08 | -0.95 | 0.02 | 0.91 | FALSE |
| 4 | GTEx | Artery Aorta | BCAR1 | 0.18 | 0.13 | lasso | 3 | 0.11 | 9.8e-07 | 5.5 | -5.4 | 6.2e-08 | -0.95 | 0.02 | 0.98 | FALSE |
| 5 | GTEx | Artery Tibial | BCAR1 | 0.07 | 0.06 | lasso | 1 | 0.04 | 2.4e-04 | 5.6 | -5.6 | 1.7e-08 | -0.97 | 0.02 | 0.97 | FALSE |
| 6 | GTEx | Cells Transformed fibroblasts | CFDP1 | 0.17 | 0.20 | enet | 10 | 0.24 | 9.9e-18 | 5.6 | 5.6 | 2.2e-08 | 0.96 | 0.02 | 0.98 | FALSE |
| 7 | GTEx | Esophagus Mucosa | BCAR1 | 0.16 | 0.13 | lasso | 8 | 0.14 | 1.8e-09 | 5.3 | 5.5 | 4.9e-08 | 0.92 | 0.03 | 0.97 | FALSE |
| 8 | GTEx | Nerve Tibial | TMEM170A | 0.12 | 0.09 | enet | 7 | 0.11 | 4.1e-08 | 4.0 | 5.4 | 6.7e-08 | 0.88 | 0.03 | 0.97 | FALSE |
| 9 | METSIM | Adipose | TMEM170A | 0.03 | 0.01 | lasso | 3 | 0.02 | 1.5e-03 | 5.5 | 5.3 | 1.5e-07 | 0.88 | 0.02 | 0.98 | FALSE |