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chr10:103,527,782-105,897,979

Best TWAS P=3.51e-12 · Best GWAS P=1.45e-10 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	AS3MT	0.17	0.16	lasso	9	0.15	4.5e-18	6.0	-6.5	9.3e-11	-0.87	0.06	0.94	FALSE
2	CommonMind	Brain Pre-frontal Cortex	C10orf32	0.43	0.54	bslmm	348	0.54	2.2e-78	6.1	-6.3	3.3e-10	-0.91	0.05	0.95	FALSE
3	GTEx	Adipose Subcutaneous	NT5C2	0.09	0.05	lasso	2	0.04	6.5e-04	6.0	6.0	2.1e-09	0.65	0.12	0.88	FALSE
4	GTEx	Adipose Visceral Omentum	NT5C2	0.13	0.07	enet	12	0.08	5.0e-05	5.0	5.8	4.9e-09	0.49	0.18	0.80	TRUE
5	GTEx	Adipose Visceral Omentum	WBP1L	0.08	0.00	enet	13	0.01	8.1e-02	5.0	6.1	1.1e-09	0.63	0.09	0.39	TRUE
6	GTEx	Artery Tibial	NT5C2	0.06	0.04	lasso	9	0.02	1.5e-02	6.0	-6.1	1.3e-09	-0.70	0.07	0.82	FALSE
7	GTEx	Artery Tibial	WBP1L	0.07	0.06	lasso	5	0.03	9.7e-04	5.9	6.3	2.5e-10	0.91	0.05	0.93	FALSE
8	GTEx	Artery Tibial	CYP17A1-AS1	0.08	0.08	lasso	8	0.06	2.8e-05	6.0	6.1	9.5e-10	0.69	0.07	0.92	FALSE
9	GTEx	Brain Cerebellar Hemisphere	NT5C2	0.15	0.10	enet	8	0.07	9.2e-03	5.7	-6.4	2.0e-10	-0.86	0.07	0.51	FALSE
10	GTEx	Brain Cerebellum	NT5C2	0.23	0.15	lasso	4	0.09	1.4e-03	5.7	-5.4	5.2e-08	-0.80	0.16	0.46	FALSE
11	GTEx	Brain Cerebellum	ARL3	0.20	0.09	enet	32	0.07	3.7e-03	5.3	5.8	7.3e-09	0.41	0.12	0.72	FALSE
12	GTEx	Brain Cortex	CYP17A1-AS1	0.15	0.13	lasso	7	0.14	1.3e-04	5.3	6.0	1.6e-09	0.61	0.09	0.72	FALSE
13	GTEx	Brain Hypothalamus	CYP17A1-AS1	0.34	0.10	lasso	10	0.05	2.6e-02	4.7	5.5	2.9e-08	0.57	0.07	0.54	FALSE
14	GTEx	Brain Nucleus accumbens basal ganglia	CYP17A1-AS1	0.39	0.22	lasso	3	0.19	8.2e-06	5.2	5.5	3.2e-08	0.57	0.20	0.20	FALSE
15	GTEx	Esophagus Mucosa	SUFU	0.08	0.02	enet	18	0.01	4.2e-02	-4.3	-6.1	1.2e-09	-0.47	0.56	0.25	FALSE
16	GTEx	Esophagus Muscularis	SUFU	0.07	0.04	enet	18	0.03	5.2e-03	-3.5	-6.1	9.3e-10	-0.54	0.27	0.54	FALSE
17	GTEx	Liver	ACTR1A	0.15	0.00	lasso	10	0.00	4.6e-01	-2.8	-6.3	3.8e-10	-0.53	0.05	0.34	FALSE
18	GTEx	Lung	CYP17A1-AS1	0.06	0.08	lasso	3	0.06	1.6e-05	5.2	5.3	1.3e-07	0.56	0.42	0.46	FALSE
19	GTEx	Muscle Skeletal	SFXN2	0.07	0.02	lasso	3	0.03	4.6e-04	5.9	5.9	4.1e-09	0.76	0.12	0.61	FALSE
20	GTEx	Nerve Tibial	SFXN2	0.30	0.22	lasso	11	0.22	1.7e-15	4.7	5.1	2.9e-07	0.57	0.86	0.14	FALSE
21	GTEx	Pancreas	CYP17A1-AS1	0.11	0.06	lasso	5	0.06	1.1e-03	6.0	5.5	4.6e-08	0.71	0.06	0.60	FALSE
22	GTEx	Uterus	TMEM180	0.22	0.00	enet	23	0.00	2.6e-01	-3.6	-5.6	1.9e-08	-0.37	0.06	0.15	FALSE
23	METSIM	Adipose	ARL3	0.04	0.00	bslmm	364	0.01	1.4e-02	3.1	5.3	1.3e-07	0.19	0.15	0.09	TRUE
24	METSIM	Adipose	AS3MT	0.24	0.28	lasso	12	0.28	6.1e-43	6.1	-6.2	4.8e-10	-0.90	0.05	0.95	FALSE
25	METSIM	Adipose	C10orf32	0.20	0.24	lasso	6	0.26	2.2e-38	6.1	-5.5	4.5e-08	-0.91	0.05	0.95	FALSE
26	METSIM	Adipose	PDCD11	0.04	0.02	bslmm	367	0.02	9.4e-04	-3.6	5.3	1.4e-07	0.44	0.20	0.12	FALSE
27	NTR	Blood	AS3MT	0.03	0.01	bslmm	351	0.02	4.4e-06	6.0	-5.5	4.5e-08	-0.77	0.06	0.93	FALSE
28	NTR	Blood	C10orf32	0.02	0.03	lasso	6	0.02	1.7e-08	6.1	-6.3	2.7e-10	-0.93	0.06	0.94	FALSE
29	ROSMAP	Brain Pre-frontal Cortex	AS3MT	0.44	0.40	enet	15	0.45	2.1e-63	6.0	-5.4	8.0e-08	-0.86	0.06	0.94	FALSE
30	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C10orf32	0.06	0.06	blup	54	0.08	1.2e-07	6.1	-7.0	3.5e-12	-0.94	0.02	0.98	TRUE
31	The Cancer Genome Atlas	Breast Invasive Carcinoma	C10orf32	0.12	0.14	enet	6	0.14	8.2e-27	6.1	-6.0	2.1e-09	-0.91	0.03	0.97	FALSE
32	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C10orf32	0.16	0.06	blup	54	0.10	1.3e-05	6.1	-6.1	1.3e-09	-0.87	0.02	0.96	TRUE
33	The Cancer Genome Atlas	Esophageal Carcinoma	C10orf32	0.19	0.25	enet	7	0.23	8.1e-08	6.1	-6.2	7.0e-10	-0.92	0.04	0.96	FALSE
34	The Cancer Genome Atlas	Glioblastoma Multiforme	AS3MT	0.15	0.05	blup	62	0.10	5.1e-04	6.1	-5.5	4.7e-08	-0.86	0.03	0.65	TRUE
35	The Cancer Genome Atlas	Glioblastoma Multiforme	C10orf32	0.27	0.09	lasso	8	0.17	7.3e-06	5.6	-6.4	1.3e-10	-0.80	0.05	0.84	FALSE
36	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AS3MT	0.05	0.05	blup	62	0.06	1.1e-07	6.1	-5.7	1.2e-08	-0.86	0.04	0.96	FALSE
37	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C10orf32	0.18	0.16	enet	9	0.17	8.0e-19	6.1	-5.9	4.7e-09	-0.91	0.04	0.96	FALSE
38	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AS3MT	0.04	0.05	enet	3	0.04	8.6e-06	6.0	-6.0	1.9e-09	-0.75	0.04	0.95	FALSE
39	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C10orf32	0.21	0.21	enet	11	0.25	3.1e-28	6.0	-6.4	1.6e-10	-0.95	0.01	0.99	FALSE
40	The Cancer Genome Atlas	Brain Lower Grade Glioma	AS3MT	0.34	0.38	lasso	6	0.38	4.4e-46	6.1	-6.3	2.7e-10	-0.89	0.04	0.96	FALSE
41	The Cancer Genome Atlas	Brain Lower Grade Glioma	C10orf32	0.21	0.19	lasso	6	0.19	2.2e-21	6.1	-6.1	1.1e-09	-0.91	0.04	0.96	FALSE
42	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C10orf32	0.08	0.07	blup	54	0.07	4.2e-04	6.0	-6.5	8.8e-11	-0.95	0.01	0.96	FALSE
43	The Cancer Genome Atlas	Lung Adenocarcinoma	C10orf32	0.14	0.21	enet	12	0.21	5.0e-24	6.0	-6.1	1.1e-09	-0.92	0.04	0.96	FALSE
44	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C10orf32	0.11	0.16	lasso	4	0.15	1.4e-16	6.1	-6.4	1.6e-10	-0.94	0.03	0.97	FALSE
45	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C10orf32	0.09	0.10	lasso	2	0.10	2.2e-07	6.1	-6.1	1.4e-09	-0.92	0.04	0.96	FALSE
46	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	AS3MT	0.15	0.21	lasso	2	0.19	1.4e-08	6.0	-6.0	2.2e-09	-0.93	0.04	0.96	TRUE
47	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C10orf32	0.36	0.32	enet	10	0.32	8.3e-14	6.1	-5.7	1.1e-08	-0.88	0.03	0.97	FALSE
48	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	AS3MT	0.13	0.14	blup	62	0.13	5.6e-06	6.0	-6.0	2.0e-09	-0.80	0.05	0.95	FALSE
49	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C10orf32	0.30	0.29	lasso	3	0.28	1.8e-11	6.0	-5.9	3.3e-09	-0.93	0.03	0.97	FALSE
50	The Cancer Genome Atlas	Prostate Adenocarcinoma	AS3MT	0.16	0.21	lasso	9	0.24	2.5e-24	6.0	-5.8	5.4e-09	-0.85	0.04	0.96	FALSE
51	The Cancer Genome Atlas	Prostate Adenocarcinoma	C10orf32	0.18	0.19	lasso	4	0.19	4.1e-19	6.1	-6.3	3.0e-10	-0.97	0.02	0.98	FALSE
52	The Cancer Genome Atlas	Prostate Adenocarcinoma	NT5C2	0.14	0.13	lasso	5	0.12	4.4e-12	5.6	-5.2	2.6e-07	-0.85	0.15	0.85	FALSE
53	The Cancer Genome Atlas	Rectum Adenocarcinoma	C10orf32	0.17	0.14	blup	52	0.14	3.2e-04	6.0	-6.7	1.7e-11	-0.81	0.03	0.69	TRUE
54	The Cancer Genome Atlas	Stomach Adenocarcinoma	C10orf32	0.19	0.21	lasso	2	0.20	1.8e-14	6.1	-6.1	1.2e-09	-0.92	0.03	0.97	FALSE
55	The Cancer Genome Atlas	Thyroid Carcinoma	AS3MT	0.23	0.18	lasso	3	0.18	1.8e-17	6.0	-6.2	6.5e-10	-0.79	0.04	0.96	FALSE
56	The Cancer Genome Atlas	Thyroid Carcinoma	C10orf32	0.27	0.27	enet	13	0.29	1.3e-28	6.1	-6.4	1.9e-10	-0.95	0.03	0.97	FALSE
57	The Cancer Genome Atlas	Thyroid Carcinoma	CYP17A1	0.04	0.02	lasso	1	0.02	3.9e-03	6.1	-6.1	1.4e-09	-0.74	0.02	0.74	FALSE