Best TWAS P=1.6e-07 · Best GWAS P=1.14e-07 conditioned to 0.189
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | C1QTNF4 | 0.26 | 0.04 | lasso | 8 | 0.02 | 1.2e-01 | 5.1 | 5.2 | 1.6e-07 | 0.91 | 0.04 | 0.24 | TRUE |
| 2 | GTEx | Testis | C1QTNF4 | 0.14 | 0.12 | lasso | 4 | 0.11 | 1.6e-05 | 4.9 | 5.2 | 2.6e-07 | 0.97 | 0.03 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | PSMC3 | 0.09 | 0.05 | blup | 39 | 0.05 | 1.0e-03 | 3.8 | -5.1 | 2.8e-07 | -0.82 | 0.00 | 0.08 | FALSE |