Best TWAS P=5.34e-09 · Best GWAS P=1.26e-07 conditioned to 0.191
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | MED19 | 0.11 | 0.04 | enet | 26 | 0.10 | 7.5e-06 | 5.1 | -5.8 | 5.3e-09 | -0.76 | 0.02 | 0.93 | TRUE |
| 2 | GTEx | Pancreas | MED19 | 0.10 | 0.08 | lasso | 3 | 0.02 | 5.0e-02 | 5.2 | -5.2 | 1.9e-07 | -0.99 | 0.02 | 0.89 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | MED19 | 0.15 | 0.11 | lasso | 7 | 0.09 | 1.3e-07 | 5.2 | -5.3 | 1.1e-07 | -0.98 | 0.01 | 0.99 | FALSE |
| 4 | YFS | Blood | ZDHHC5 | 0.06 | 0.07 | enet | 20 | 0.07 | 1.2e-22 | 5.1 | 5.7 | 1.0e-08 | 0.96 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | TMX2 | 0.07 | 0.06 | lasso | 1 | 0.05 | 5.0e-04 | 5.2 | 5.2 | 1.7e-07 | 0.99 | 0.00 | 0.90 | FALSE |
| 6 | The Cancer Genome Atlas | Esophageal Carcinoma | MED19 | 0.10 | 0.06 | lasso | 4 | 0.02 | 5.4e-02 | 5.3 | -5.3 | 1.3e-07 | -1.00 | 0.00 | 0.83 | FALSE |