Best TWAS P=5.7e-09 · Best GWAS P=3.03e-11 conditioned to 0.033
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | GTF3A | 0.15 | 0.11 | enet | 26 | 0.13 | 4.1e-15 | -3.9 | 5.1 | 2.7e-07 | -0.74 | 0.09 | 0.91 | FALSE |
| 2 | GTEx | Muscle Skeletal | MTIF3 | 0.12 | 0.03 | lasso | 5 | 0.03 | 1.2e-03 | -5.2 | -5.4 | 6.5e-08 | 0.74 | 0.07 | 0.89 | FALSE |
| 3 | GTEx | Nerve Tibial | AL137059.1 | 0.10 | 0.02 | lasso | 3 | 0.03 | 2.9e-03 | 3.9 | -5.8 | 5.7e-09 | 0.71 | 0.02 | 0.94 | TRUE |
| 4 | YFS | Blood | MTIF3 | 0.07 | 0.05 | enet | 19 | 0.06 | 1.6e-18 | -3.9 | -5.2 | 2.6e-07 | 0.77 | 0.76 | 0.24 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GTF3A | 0.03 | 0.00 | enet | 8 | 0.01 | 2.3e-02 | 1.3 | 5.7 | 1.4e-08 | -0.63 | 0.01 | 0.84 | TRUE |