[Hub]/) : Traits : Body mass index (BMI) :

chr13:32,305,370-34,332,027

Best TWAS P=4.52e-11 · Best GWAS P=5.91e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-298P3.4 0.09 0.01 lasso 7 0.00 1.9e-01 -5.9 -6.2 5.6e-10 0.84 0.06 0.87 FALSE
2 GTEx Artery Aorta N4BP2L2 0.13 0.10 lasso 3 0.09 1.1e-05 -6.5 -6.3 3.3e-10 0.98 0.01 0.98 FALSE
3 GTEx Whole Blood KL 0.12 0.00 lasso 7 0.00 4.9e-01 -2.7 5.9 4.8e-09 -0.58 0.12 0.17 FALSE
4 YFS Blood PDS5B 0.03 0.04 lasso 1 0.03 1.4e-11 -5.3 -5.3 1.4e-07 0.81 0.29 0.71 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma CG030 0.04 0.01 lasso 3 0.02 2.1e-04 -6.5 6.3 3.2e-10 -0.97 0.00 1.00 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma N4BP2L2 0.02 0.02 lasso 2 0.01 1.4e-03 -6.5 -6.4 1.7e-10 1.00 0.01 0.97 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CG030 0.07 0.02 lasso 4 0.03 2.4e-04 -6.1 5.8 6.4e-09 -0.83 0.01 0.66 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma N4BP2L2 0.04 0.03 blup 69 0.02 9.4e-04 -6.5 -6.0 2.1e-09 0.97 0.01 0.98 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma CG030 0.06 0.01 blup 38 0.02 1.9e-03 3.4 5.3 9.0e-08 -0.82 0.02 0.89 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma N4BP2L2 0.10 0.10 lasso 4 0.11 5.2e-12 -6.5 -6.1 1.1e-09 0.97 0.00 1.00 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma N4BP2L2 0.04 0.04 lasso 2 0.03 1.5e-04 -6.5 -6.6 4.5e-11 0.99 0.00 0.99 TRUE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CG030 0.08 0.04 blup 38 0.04 1.4e-03 -6.1 6.1 8.4e-10 -0.92 0.00 0.91 FALSE
13 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CG030 0.12 0.02 blup 38 0.03 3.1e-02 -6.1 6.1 1.1e-09 -0.82 0.00 0.59 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma N4BP2L2 0.06 0.03 lasso 3 0.05 1.0e-05 4.8 -5.9 2.7e-09 0.79 0.02 0.97 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma N4BP2L2 0.12 0.14 enet 7 0.16 1.1e-15 -5.8 -6.3 2.7e-10 0.98 0.01 0.99 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma PDS5B 0.02 0.01 blup 78 0.02 1.2e-02 -6.0 5.8 5.1e-09 -0.92 0.02 0.78 FALSE