TWAS hub - N4BP2L2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adrenal Gland	0.2579	0.0902	3.5e-03	0.118	NA	0.022	NA	0.077	5.2e-05	NA	5.4e-02	NA	1.0e-03
2	GTEx	Artery Aorta	0.1280	0.0480	6.8e-04	0.103	NA	0.054	NA	0.091	2.6e-06	NA	5.8e-04	NA	1.1e-05
3	TCGA	Breast Invasive Carcinoma	0.0173	0.0098	4.0e-03	0.016	0.010	0.009	NA	0.012	2.9e-04	3.2e-03	4.8e-03	NA	1.4e-03
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.0355	0.0177	2.5e-03	0.027	0.024	0.020	NA	0.023	4.0e-04	9.4e-04	2.3e-03	NA	1.2e-03
5	TCGA	Brain Lower Grade Glioma	0.0996	0.0345	4.4e-11	0.104	0.095	0.105	NA	0.106	8.5e-12	5.9e-11	6.7e-12	NA	5.2e-12
6	TCGA	Lung Adenocarcinoma	0.0329	0.0167	2.1e-03	0.016	0.018	0.018	NA	0.018	4.8e-03	3.2e-03	3.0e-03	NA	2.8e-03
7	TCGA	Lung Squamous Cell Carcinoma	0.0366	0.0205	9.3e-04	0.042	0.017	0.017	NA	0.032	1.3e-05	4.6e-03	4.2e-03	NA	1.5e-04
8	TCGA	Prostate Adenocarcinoma	0.0641	0.0311	5.3e-05	0.032	0.037	0.045	NA	0.047	2.2e-04	8.5e-05	1.8e-05	NA	1.0e-05
9	TCGA	Thyroid Carcinoma	0.1180	0.0370	2.8e-13	0.135	0.145	0.163	NA	0.158	4.4e-13	5.2e-14	1.1e-15	NA	3.7e-15

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Blood Platelet Count	10.8	125.5	159.3	1.4	12.4	12.6	11.9	12.5	12.1	12.3	8.4	12.3
BMI	9.3	54.0	72.7	0.7	-8.1	-8.3	-7.8	-7.7	-6.6	-8.5	-7.2	-8.0
Body mass index (BMI)	7.8	33.1	43.4	0.2	-6.3	-6.4	-6.0	-6.1	-5.1	-6.6	-5.9	-6.3
Body Mass Index (BMI) (2010)	7.2	9.8	13.0	1.0	-3.5	-3.6	-3.4	-3.4	-3.1	-3.6	-2.3	-3.4
Hypothyroidism (self reported)	7.2	16.5	21.3	-0.4	-4.6	-4.6	-4.1	-4.4	-4.2	-4.6	-3.4	-4.5
Medication: Aspirin	6.5	8.6	12.0	1.9	-3.0	-3.0	-3.4	-3.4	-3.5	-2.8	-1.7	-3.3
Medication: Levothyroxine sodium	6.4	10.9	14.1	0.3	-3.7	-3.7	-3.4	-3.5	-3.0	-3.8	-3.2	-3.6
Arm fat percentage (left)	6.4	25.5	34.3	0.2	-5.4	-5.7	-5.3	-5.3	-4.5	-5.9	-5.2	-5.5
Arm fat percentage (right)	6.0	23.7	31.5	0.3	-5.2	-5.5	-5.1	-5.1	-4.3	-5.6	-5.0	-5.3
Leg fat percentage (left)	5.8	20.9	29.5	0.3	-4.9	-5.2	-4.5	-4.7	-3.7	-5.4	-5.2	-5.0
Medication: Ibuprofen (e.g. Nurofen)	5.5	7.0	9.1	-0.7	2.9	2.9	2.8	2.9	2.7	2.9	2.2	3.0
Comparative height size at age 10	5.5	30.1	40.2	2.1	6.2	6.3	5.9	5.8	5.7	6.2	3.9	5.8
Hypothyroidism/myxoedema (self-reported)	5.3	10.3	13.7	0.4	-3.6	-3.7	-3.2	-3.3	-3.1	-3.7	-3.0	-3.5
Medication: Aspirin	5.3	6.9	8.6	2.2	-2.7	-2.6	-2.9	-2.9	-2.8	-2.5	-1.8	-2.9
Illness, injury, bereavement, stress in last 2 years	5.1	6.3	8.3	-0.1	2.7	2.8	2.8	2.7	2.1	2.9	2.5	2.8
Height	4.9	95.4	125.4	0.6	11.2	10.7	11.0	10.5	10.1	10.4	8.3	10.4
Leg fat percentage (right)	4.9	17.7	24.9	0.6	-4.5	-4.7	-4.3	-4.3	-3.3	-5.0	-4.9	-4.6
Medication: Cholesterol lowering	4.8	7.4	10.7	0.3	-3.2	-2.8	-3.0	-3.1	-3.3	-2.6	-2.0	-2.9
Arm fat mass (left)	4.6	19.1	25.0	0.3	-4.6	-4.9	-4.5	-4.7	-3.9	-5.0	-4.7	-4.8
Glaucoma (self-reported)	4.5	5.2	6.5	1.4	2.5	2.2	2.5	2.4	2.1	2.3	2.5	2.5
Osteoarthritis (self-reported)	4.5	5.8	9.1	0.1	3.0	2.7	2.7	2.7	2.8	2.5	1.3	2.5
Type 2 Diabetes (T2D) (2012)	4.4	5.1	7.7	-1.3	-2.3	-2.2	-2.4	-2.4	-1.4	-2.6	-2.8	-2.6
Arm fat mass (right)	4.3	17.5	23.3	0.3	-4.4	-4.7	-4.3	-4.4	-3.7	-4.8	-4.5	-4.6
Hair/balding pattern: Pattern 2	4.1	5.3	7.5	1.3	-2.3	-2.7	-2.4	-2.4	-2.1	-2.7	-2.0	-2.4
Leg fat mass (left)	4.1	16.0	22.7	0.3	-4.3	-4.5	-4.0	-4.2	-3.2	-4.8	-4.4	-4.4
Heel T-Score	4.0	32.0	42.8	0.6	-6.5	-6.0	-5.9	-6.2	-5.6	-6.1	-5.3	-6.3
Age when periods started (menarche)	4.0	9.5	13.6	-0.7	3.4	3.4	3.3	3.2	2.7	3.7	2.6	3.5
Handedness (chirality/laterality): Left-handed	4.0	4.8	6.4	0.2	-2.5	-2.3	-2.5	-2.4	-2.5	-2.2	-1.5	-2.4
Standing height	3.9	38.3	51.0	-0.4	7.1	6.8	6.9	6.5	6.2	6.7	5.4	6.7
Body fat percentage	3.9	15.3	22.1	0.2	-4.2	-4.4	-3.8	-3.9	-3.1	-4.7	-4.5	-4.2
Leg fat mass (right)	3.9	15.1	21.5	0.5	-4.2	-4.4	-4.0	-4.0	-3.0	-4.6	-4.4	-4.3
Average weekly champagne plus white wine intake	3.7	5.1	7.9	1.1	2.2	2.3	2.2	2.4	2.3	2.2	2.8	2.4
Medication for cholesterol, blood pressure or diabetes	3.6	6.0	9.2	-0.4	2.7	2.7	2.7	2.8	3.0	2.5	1.3	2.6
Medication: Amlodipine	3.6	5.1	7.1	0.3	-2.4	-2.5	-2.6	-2.6	-2.7	-2.5	-0.4	-2.6
Impedance of leg (right)	3.5	16.7	21.5	0.4	4.4	4.5	4.6	4.6	4.3	4.4	3.2	4.6
Chest pain or discomfort	3.5	5.0	6.7	1.8	-2.6	-2.3	-2.2	-2.5	-2.5	-2.2	-1.3	-2.4
Eye problems/disorders: Glaucoma	3.4	4.0	6.5	1.4	2.1	1.9	2.1	2.1	1.5	2.1	2.5	2.2
Whole body fat mass	3.3	13.9	19.7	0.1	-4.0	-4.2	-3.7	-3.9	-3.1	-4.4	-4.2	-4.1
Alcohol drinker status: Previous	3.2	3.6	4.6	1.5	2.1	2.1	1.9	2.0	1.6	2.1	1.6	2.0
Impedance of whole body	3.1	15.6	19.6	-0.3	4.2	4.2	4.4	4.4	4.0	4.2	3.7	4.4
Medication: Blood pressure	3.0	5.3	7.6	-0.5	-2.5	-2.8	-2.6	-2.5	-2.4	-2.7	-0.8	-2.5
Hand grip strength (left)	2.9	7.8	10.5	-2.1	-3.2	-3.1	-3.0	-2.8	-2.5	-3.0	-2.5	-2.7
Serious illness, injury or assault to yourself	2.9	3.5	4.6	1.3	-2.2	-2.0	-2.1	-1.9	-1.7	-2.0	-1.7	-1.9
Hair/balding pattern: Pattern 3	2.9	4.4	6.2	-1.1	2.1	2.5	2.1	2.3	2.4	2.3	1.7	2.1
Comparative body size at age 10	2.9	7.9	12.4	-0.9	-3.1	-2.7	-3.1	-2.9	-2.1	-3.0	-3.5	-3.1
Migraine (self-reported)	2.9	3.5	5.9	-0.9	2.4	2.1	1.8	2.1	1.9	2.1	1.0	2.0
Hayfever/allergic rhinitis (self-reported)	2.8	3.8	5.1	-1.2	2.2	2.1	2.3	2.0	1.8	2.2	1.3	2.1
Medication: Lansoprazole	2.8	3.2	14.4	3.8	-1.5	-1.5	-1.3	-1.4	-1.7	-1.3	-0.0	-1.3
Diastolic blood pressure, automated reading	2.8	8.7	12.4	-2.5	-3.1	-3.5	-2.7	-3.0	-3.4	-3.2	-2.0	-2.9
Impedance of arm (left)	2.7	12.5	15.1	-0.7	3.9	3.7	3.8	3.8	3.2	3.8	3.8	3.9
Shortness of breath walking on level ground	2.7	3.2	5.9	0.2	-2.1	-1.8	-1.8	-1.7	-1.3	-1.9	-2.4	-1.9
Heart disease (mother)	2.7	3.3	5.3	-1.2	-1.7	-1.9	-1.8	-2.0	-2.3	-1.7	-1.6	-1.9
Overall health rating	2.7	5.9	7.2	0.9	-2.4	-2.7	-2.7	-2.4	-2.6	-2.5	-2.5	-2.5
Impedance of leg (left)	2.6	12.6	17.2	0.1	3.8	3.8	4.1	4.1	3.7	3.7	2.8	3.9
Impedance of arm (right)	2.6	12.3	15.0	-0.3	3.8	3.8	3.7	3.8	3.2	3.9	3.7	3.9
Depression (self-reported)	2.6	3.2	4.2	1.1	1.8	1.9	2.0	2.0	1.8	1.9	1.2	2.1
Number of children fathered	2.6	2.9	3.6	0.2	-1.7	-1.8	-1.8	-1.8	-1.9	-1.8	-1.7	-1.9
Coronary Artery Disease (CAD)	2.5	3.0	5.6	1.3	-1.8	-1.6	-1.6	-1.8	-1.2	-1.7	-2.4	-1.9
Maternal smoking around birth	2.5	3.6	5.4	-0.1	-2.3	-2.1	-2.0	-2.0	-1.9	-2.0	-1.7	-1.9
Waist circumference	2.5	9.0	13.5	0.3	-3.2	-3.4	-3.0	-3.0	-2.1	-3.7	-3.5	-3.3
Father’s age at death	2.5	3.4	6.1	1.2	1.6	2.0	2.1	1.7	1.8	1.9	2.5	1.7
Ever smoked	2.5	4.4	6.2	1.1	-2.3	-2.2	-2.2	-2.3	-1.8	-2.4	-1.7	-2.5
Tinnitus: Yes, but not now, but have in the past	2.4	2.5	4.9	1.3	-1.7	-1.6	-1.6	-1.9	-2.2	-1.3	-0.7	-1.6
Blood clot in the leg (DVT)	2.4	3.1	4.5	1.9	-1.6	-2.1	-1.9	-1.6	-1.4	-2.1	-1.3	-1.7
Worry too long after embarrassment	2.4	4.1	5.8	1.0	2.1	2.2	2.1	2.3	1.9	2.3	1.4	2.4
Medication: Ibuprofen	2.4	2.9	4.0	-0.3	1.9	1.7	1.8	2.0	1.9	1.7	1.5	2.0
Forced expiratory volume in 1-second (FEV1), predicted	2.4	4.9	7.8	-1.3	2.8	2.5	2.2	2.2	2.0	2.6	1.3	2.5
Vascular/heart problems diagnosed by doctor	2.4	6.4	8.1	2.3	2.7	2.8	2.7	2.7	2.9	2.6	0.9	2.6
Heel bone mineral density (BMD) T-score, automated (left)	2.3	5.3	6.6	-1.0	-2.6	-2.3	-2.6	-2.5	-2.5	-2.3	-2.1	-2.5
Sitting height	2.3	16.2	23.7	-0.1	4.9	4.3	4.3	4.3	4.4	4.2	3.5	4.3
Heart attack	2.3	2.9	5.1	-0.1	-2.3	-1.8	-1.9	-1.7	-1.5	-1.9	-1.2	-1.9
Hip circumference	2.3	9.9	14.8	-0.2	-3.3	-3.6	-3.2	-3.2	-2.4	-3.8	-3.6	-3.4
Illnesses of mother	2.3	2.9	5.8	2.4	1.6	1.6	1.6	1.7	1.7	1.5	1.4	1.7
Medication: Allopurinol	2.3	3.0	5.5	0.7	-2.4	-2.0	-1.9	-1.6	-1.6	-2.0	-1.5	-1.6
Cardiovascular Disease	2.1	6.8	10.7	-1.4	-2.6	-3.1	-2.9	-2.9	-3.3	-2.7	-0.8	-2.7
Angina	2.1	2.8	4.8	-0.7	-1.9	-1.8	-1.7	-1.8	-2.2	-1.6	-1.2	-1.7
Trunk fat percentage	2.1	8.6	13.0	-0.1	-3.1	-3.3	-2.8	-2.9	-2.2	-3.6	-3.5	-3.2
Supplements: Glucosamine	2.1	2.7	4.8	1.2	1.4	1.8	2.2	1.7	1.2	2.0	1.3	1.8
Hand grip strength (right)	1.9	5.3	7.0	-0.8	-2.6	-2.6	-2.6	-2.4	-2.3	-2.4	-2.2	-2.2
Heart attack/myocardial infarction (self-reported)	1.9	2.5	4.7	0.1	-2.2	-1.7	-1.8	-1.6	-1.3	-1.9	-1.0	-1.8
Vitamin and mineral supplements	1.8	2.4	3.8	-0.8	-1.9	-1.5	-1.8	-1.3	-0.7	-1.8	-1.8	-1.6
Trunk fat mass	1.8	7.9	12.2	0.0	-2.9	-3.2	-2.6	-2.8	-2.0	-3.5	-3.5	-3.1
Hearing difficulty/problems with background noise	1.8	2.9	5.3	0.6	-1.7	-2.0	-2.0	-1.9	-2.3	-1.7	-0.4	-1.7
Medication: Simvastatin	1.8	2.6	3.8	0.4	-1.9	-1.5	-1.9	-1.8	-1.9	-1.4	-1.2	-1.8
Alcohol intake versus 10 years previously	1.8	2.7	4.1	0.2	-1.7	-1.9	-2.0	-1.9	-1.7	-1.8	-0.9	-1.8
Alzheimer’s Disease (in mother)	1.7	1.9	2.5	0.9	1.4	1.4	1.3	1.6	1.6	1.4	1.2	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	3.5	1.7	-1.3	-1.3	-1.8	-1.5	-1.9	-1.0	-1.5	-1.3
Number of incorrect matches in round	1.7	2.8	3.6	0.2	1.8	1.9	1.8	1.8	1.6	1.9	1.7	1.8
Eye problems/disorders: Cataract	1.7	2.0	3.2	-0.0	-1.6	-1.5	-1.6	-1.8	-1.8	-1.4	-0.2	-1.7
Breast cancer (self-reported)	1.7	2.0	2.9	-0.3	-1.4	-1.6	-1.6	-1.6	-1.1	-1.7	-1.0	-1.7
Osteoporosis (self-reported)	1.7	2.1	2.8	-0.2	1.6	1.7	1.6	1.6	1.4	1.7	0.9	1.6
Heart disease (siblings)	1.7	2.1	2.6	1.4	-1.6	-1.6	-1.5	-1.5	-1.4	-1.5	-0.9	-1.5
Frequency of depressed mood in last 2 weeks	1.6	2.3	6.1	2.5	-1.2	-1.3	-1.8	-1.3	-1.4	-1.1	-1.3	-1.2
Angina (self-reported)	1.6	2.1	4.3	-0.5	-1.7	-1.5	-1.5	-1.6	-2.1	-1.2	-0.9	-1.4
Supplements: Vitamin C	1.6	1.8	2.9	0.6	1.6	1.4	1.7	1.4	1.0	1.5	0.9	1.5
Hypertension (Self-reported)	1.6	4.4	5.8	-1.1	-2.3	-2.4	-2.3	-2.4	-2.4	-2.3	-0.7	-2.3
Basal cell carcinoma (self-reported)	1.6	1.9	2.6	0.8	-1.4	-1.4	-1.6	-1.5	-1.2	-1.5	-1.4	-1.5
Primary Biliary Cirrhosis	1.5	2.1	3.6	0.3	-1.7	-1.6	-1.9	-1.6	-1.6	-1.5	-0.6	-1.6
High blood pressure	1.5	4.0	5.0	-2.0	-2.1	-2.2	-2.2	-2.2	-2.2	-2.1	-0.4	-2.1
Had other major operations	1.5	1.8	3.1	1.1	-1.5	-1.1	-1.5	-1.5	-1.8	-0.9	-1.0	-1.5
Weight	1.5	7.5	10.6	-0.0	-2.8	-3.1	-2.7	-2.9	-2.2	-3.3	-3.2	-3.0
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.4	3.9	2.0	-1.4	-1.5	-1.6	-1.5	-1.3	-1.5	-1.4	-1.5
Birth weight of first child	1.5	2.6	4.7	-0.8	1.6	1.8	1.6	1.8	2.2	1.7	0.6	1.8
Loud music exposure frequency	1.5	1.7	3.3	-1.7	-1.1	-1.1	-1.5	-1.3	-1.8	-0.8	-0.7	-1.1
Wheeze or whistling in the chest in last year	1.5	2.8	5.5	-0.5	-1.6	-1.9	-1.9	-2.0	-2.3	-1.6	0.3	-1.7
Qualifications: College or University degree	1.5	4.8	7.0	-0.2	2.7	2.5	2.3	2.1	1.9	2.6	2.0	2.3
Commuting to job workplace: Car/motor vehicle	1.5	1.7	4.1	0.2	-1.4	-1.2	-1.2	-1.3	-0.9	-1.4	-2.0	-1.4
Depression (Nagel 2018)	1.4	2.1	3.6	1.5	-1.3	-1.2	-1.9	-1.4	-1.5	-1.1	-1.5	-1.3
Type 2 Diabetes (T2D) (2018)	1.4	2.6	4.0	2.0	-1.6	-1.4	-2.0	-1.7	-1.3	-1.5	-1.1	-1.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.1	3.4	1.9	-1.1	-1.5	-1.4	-1.5	-1.5	-1.4	-1.3	-1.4
Birth weight	1.4	3.0	5.0	-0.9	1.6	2.0	2.1	1.8	2.2	1.7	0.9	1.8
Medication: Omeprazole	1.4	1.7	2.6	-1.2	-1.0	-1.6	-1.3	-1.2	-1.2	-1.6	-1.1	-1.2
Pulse rate, automated reading	1.4	4.6	6.3	0.1	2.5	2.4	2.3	2.4	2.5	2.3	1.4	2.3
Pack years of smoking	1.4	2.0	3.4	1.4	-1.3	-1.5	-1.7	-1.5	-1.8	-1.3	-0.3	-1.4
Past tobacco smoking	1.3	2.4	3.2	-1.1	1.8	1.7	1.6	1.5	1.2	1.8	1.5	1.7
Hair/balding pattern: Pattern 4	1.3	3.2	4.2	0.1	-2.1	-2.1	-1.6	-1.8	-2.0	-2.0	-1.9	-1.8
Mouth/teeth dental problems: Loose teeth	1.3	1.6	4.0	0.5	-1.1	-1.3	-1.4	-1.5	-2.0	-1.0	-0.4	-1.2
Rheumatoid Arthritis	1.2	1.7	3.7	1.9	1.2	0.8	1.6	1.1	1.1	0.7	1.8	1.0
Tanning	1.2	14.1	19.5	-0.5	3.9	4.1	4.1	4.3	4.4	3.7	3.3	4.0
Pack years adult smoking proportion	1.2	1.9	2.9	1.1	-1.3	-1.5	-1.7	-1.5	-1.7	-1.3	-0.4	-1.4
Multivitamins +/- minerals	1.2	1.6	2.3	0.0	1.4	1.3	1.5	1.2	0.7	1.5	1.5	1.4
Loneliness, isolation	1.2	1.7	12.0	3.5	-0.5	-0.6	-0.5	-0.6	-0.1	-0.8	-0.8	-0.7
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	4.0	2.0	-1.0	-1.4	-1.2	-0.9	-0.7	-1.6	-0.8	-1.1
Crohns Disease (2017)	1.1	2.4	2.9	1.4	1.6	1.7	1.4	1.7	1.4	1.6	1.4	1.6
Systolic blood pressure, automated reading	1.1	3.3	7.6	-2.8	-1.8	-1.8	-1.7	-1.7	-2.4	-1.4	-0.6	-1.5
Qualifications: None of the above	1.1	2.4	3.6	-1.1	-1.7	-1.5	-1.9	-1.6	-1.4	-1.5	-1.4	-1.7
Number of live births	1.1	1.6	4.6	1.2	-1.0	-1.3	-1.5	-1.3	-2.2	-0.8	-0.5	-0.8
Gout (self-reported)	1.1	1.6	2.9	0.4	-1.6	-1.6	-1.2	-1.0	-0.8	-1.7	-1.2	-1.2
Chronic bronchitis/emphysema (mother)	1.1	1.3	1.9	-1.1	-1.3	-1.4	-1.0	-1.1	-1.1	-1.4	-0.5	-1.1
Leg pain on walking	1.1	1.4	2.3	1.3	-1.1	-1.2	-1.0	-1.4	-1.2	-1.2	-0.4	-1.5
Irritability	1.1	1.9	2.9	1.7	-1.3	-1.3	-1.2	-1.2	-0.3	-1.7	-1.6	-1.4
Prostate Cancer	1.0	1.4	2.2	0.5	-1.0	-1.5	-1.0	-1.4	-1.4	-1.4	-0.8	-1.4
Triglycerides	1.0	1.7	2.8	0.2	-1.4	-1.4	-1.1	-1.3	-0.9	-1.5	-1.7	-1.4
Medication: Metformin	1.0	1.4	4.8	2.2	-1.2	-0.8	-1.3	-0.9	-0.5	-1.0	-0.8	-1.1
Diabetes (mother)	1.0	1.3	2.7	1.7	-0.9	-0.9	-1.1	-1.1	-0.9	-1.0	-1.2	-1.3
Pain all over the body in last month	1.0	1.0	2.9	1.7	0.7	0.9	0.9	0.8	1.0	0.8	1.1	0.8
Worrier / anxious feelings	1.0	1.8	3.3	1.0	1.5	1.4	0.9	1.2	1.0	1.6	1.8	1.5
Pulse rate	1.0	1.8	4.1	-0.3	1.7	1.1	1.3	1.2	0.8	1.3	2.0	1.4
Commuting to job workplace: Public transport	1.0	1.2	2.0	-0.2	1.1	1.1	1.2	1.2	1.4	0.9	1.3	1.1
Medication: Blood pressure	1.0	1.9	4.3	-2.1	-1.4	-1.1	-1.2	-1.4	-1.2	-1.2	-0.9	-1.5
Alcohol drinker status: Never	1.0	1.2	1.7	-0.6	1.3	1.2	0.9	1.1	0.7	1.3	1.3	1.2
Unable to work because of sickness or disability	1.0	1.3	11.8	3.4	0.1	0.2	0.0	0.1	0.2	0.1	-0.3	0.1
Worry (Nagel 2018)	0.9	1.8	5.2	0.8	1.3	1.3	0.8	1.1	1.1	1.4	2.3	1.3
Chronotype (morning person)	0.9	2.2	4.0	-2.0	1.5	1.7	1.3	1.3	1.3	1.6	0.8	1.3
Average weekly fortified wine intake	0.9	1.0	1.8	-0.1	1.3	1.1	1.0	1.0	0.6	1.3	0.8	1.1
Ever highly irritable/argumentative for 2 days	0.9	1.1	1.8	0.8	-1.4	-0.9	-0.9	-1.1	-1.1	-0.9	-1.1	-1.1
Exposure to tobacco smoke outside home	0.9	1.2	2.7	-1.7	-0.9	-1.1	-1.2	-1.1	-1.0	-1.2	0.1	-1.2
Neck or shoulder pain in last month	0.9	1.3	2.4	1.1	1.5	1.1	1.4	1.2	0.9	1.2	0.3	1.2
Diabetes diagnosed by doctor	0.9	1.5	2.5	1.2	-1.4	-0.9	-1.6	-1.2	-0.6	-1.1	-1.2	-1.3
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	2.3	0.3	1.5	1.1	1.4	1.2	0.7	1.3	1.4	1.4
High cholesterol (Self-reported)	0.9	1.5	4.2	-0.7	-1.2	-1.1	-1.4	-1.3	-2.1	-0.7	-0.9	-1.1
Schizophrenia (2018)	0.8	1.8	2.6	1.6	1.4	1.1	1.4	1.3	0.9	1.2	1.5	1.4
Hearing difficulty/problems: Yes	0.8	1.2	1.7	-0.8	-0.7	-1.3	-1.1	-1.3	-1.3	-1.3	-0.4	-1.3
Medication for hormone replacement therapy	0.8	0.9	1.8	0.7	0.6	1.0	1.1	1.2	1.3	0.9	0.4	1.1
Relative age voice broke	0.8	1.1	4.6	-1.1	0.8	0.7	0.8	0.8	0.5	0.9	2.1	1.0
Alcohol usually taken with meals	0.8	1.3	3.6	1.9	1.0	0.8	1.2	1.1	0.9	0.8	1.1	1.1
Medication: Ramipril	0.8	1.0	4.1	-2.0	-0.8	-0.6	-0.5	-0.5	0.0	-0.9	-1.6	-0.7
Mouth/teeth dental problems: Dentures	0.8	1.3	2.7	-1.6	-0.8	-1.0	-1.3	-1.3	-1.3	-0.9	-0.4	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.4	4.0	0.0	2.0	1.8	1.5	1.7	1.5	1.9	0.8	1.8
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	1.9	-0.7	-0.8	-1.4	-1.0	-0.9	-0.9	-1.3	-1.0	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	1.6	0.2	0.8	0.9	1.1	1.2	1.1	0.8	0.6	1.1
Age at first live birth	0.8	1.5	3.0	-0.1	1.1	1.2	1.6	1.3	1.7	0.9	1.0	1.2
Alcohol intake frequency.	0.8	1.9	4.1	2.0	-1.1	-1.2	-1.7	-1.2	-1.3	-1.0	-1.2	-1.1
Illnesses of father: Heart disease	0.8	1.1	3.1	-0.6	-0.9	-1.3	-1.0	-1.1	-1.8	-0.9	-0.1	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	1.5	0.1	1.1	1.1	1.2	0.8	0.8	1.2	0.8	1.0
Illnesses of father: None of the above (group 1)	0.8	1.0	1.6	0.8	0.9	1.2	1.1	0.9	1.3	1.0	0.4	0.9
Ever taken oral contraceptive pill	0.8	0.9	1.4	1.2	0.6	1.0	1.0	1.0	1.0	1.0	0.3	1.0
Mother’s age at death	0.8	1.0	2.3	-1.5	0.9	0.8	1.0	0.8	0.2	1.0	1.4	1.0
Pain type(s) experienced in last month: Hip pain	0.8	1.1	2.4	1.2	1.1	1.3	1.0	0.8	0.3	1.6	0.6	1.0
Medication: Bendroflumethiazide	0.8	1.3	3.3	-0.8	1.0	1.3	0.8	1.1	1.8	1.0	0.8	1.0
Cholesterol lowering medication	0.8	1.2	1.7	0.9	-1.3	-1.1	-1.3	-1.2	-1.2	-1.0	-0.2	-1.1
Reaction Time	0.7	1.4	2.1	1.4	1.2	1.0	1.1	1.2	1.4	0.9	0.9	1.2
Systolic Blood Pressure	0.7	3.7	12.4	-3.5	-1.7	-1.6	-1.8	-1.7	-2.7	-1.0	0.5	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	2.6	-0.2	-1.5	-1.2	-1.4	-1.3	-1.3	-1.2	-1.6	-1.3
Diabetes (self-reported)	0.7	1.1	2.0	1.1	-1.2	-0.7	-1.4	-1.1	-0.9	-0.8	-0.8	-1.2
Happiness	0.7	0.9	1.5	1.2	0.9	0.9	1.0	1.1	0.9	1.0	0.2	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.8	1.3	-0.5	-0.6	-0.7	-0.4	0.0	-0.8	-1.7	-0.6
Lung cancer (father)	0.7	0.8	2.3	0.8	-1.1	-0.6	-1.0	-0.5	-0.3	-0.8	-1.5	-0.7
Pulse wave Arterial Stiffness index	0.7	0.9	1.4	0.6	0.8	1.0	1.2	1.1	0.9	1.0	0.2	1.1
Tense / ‘highly strung’	0.7	1.1	8.6	2.9	0.2	0.1	0.1	0.2	0.2	0.2	1.1	0.2
Qualifications: O levels/GCSEs or equivalent	0.7	1.2	2.6	0.2	1.3	0.9	1.1	1.0	0.9	1.0	1.6	1.2
Suffer from ‘nerves’	0.7	1.1	1.6	0.9	1.1	1.2	0.8	1.0	1.3	1.1	1.1	0.9
Age at last live birth	0.7	0.9	2.5	-1.4	0.8	0.6	1.0	0.7	0.6	0.7	1.6	0.9
Medication for cholesterol	0.7	1.1	2.7	1.6	1.1	0.9	0.9	1.1	1.1	0.9	0.6	1.1
Leg predicted mass (right)	0.7	3.5	4.6	-0.8	-1.8	-2.1	-1.9	-2.1	-1.6	-2.2	-2.0	-2.1
Average weekly beer plus cider intake	0.7	1.0	1.7	-0.2	-1.2	-1.3	-1.0	-1.1	-1.3	-1.1	0.3	-1.0
Fractured/broken bones in last 5 years	0.7	0.8	2.1	-1.4	-0.9	-1.0	-0.8	-0.7	-1.0	-0.8	-0.7	-0.6
Bipolar Disorder (2018)	0.6	0.9	2.2	0.7	-0.9	-0.8	-0.8	-1.1	-0.6	-0.9	-1.5	-1.1
Schizophrenia vs Biploar Disorder	0.6	0.7	1.4	-1.2	0.9	0.7	0.7	0.9	0.1	0.9	0.9	1.0
Breast Cancer	0.6	1.3	1.8	-1.3	-1.2	-1.3	-1.0	-1.2	-1.3	-1.2	0.3	-1.1
Age at First Birth	0.6	0.8	1.3	0.2	1.0	0.9	1.0	1.1	0.9	0.9	0.7	1.1
Smoking Status	0.6	1.5	2.6	1.4	-1.5	-1.1	-1.6	-1.1	-0.6	-1.2	-0.9	-1.2
High blood pressure (mother)	0.6	0.8	6.6	-2.6	-0.4	-0.3	-0.5	-0.4	-0.3	-0.3	-0.3	-0.4
Falls in the last year	0.6	0.9	4.0	0.4	1.0	0.7	0.8	0.4	0.0	1.0	2.0	0.7
Breastfed as a baby	0.6	0.8	3.0	-1.7	-0.6	-0.9	-0.4	-0.7	-1.3	-0.6	0.2	-0.4
Forced vital capacity (FVC), Best measure	0.6	2.3	3.9	-0.3	1.9	1.7	1.4	1.5	1.1	2.0	1.2	1.8
Health satisfaction	0.6	0.8	1.2	-0.1	-1.0	-1.0	-0.9	-0.7	-0.8	-1.0	-1.1	-0.8
Eye problems/disorders: None of the above	0.6	0.6	2.3	-0.2	-0.8	-0.6	-0.7	-0.7	-0.4	-0.7	-1.5	-0.8
Mean time to correctly identify matches	0.6	1.2	1.9	1.4	1.1	1.0	1.0	1.2	1.4	0.8	0.5	1.1
Knee pain experienced in last month	0.6	0.9	2.5	1.6	-0.8	-0.9	-0.5	-0.8	-0.4	-1.1	-0.9	-1.0
Smoking status: Previous	0.6	1.0	3.7	1.9	-1.0	-0.9	-0.7	-0.5	-0.5	-1.0	-0.9	-0.7
Leg fat-free mass (right)	0.6	3.4	4.5	-0.7	-1.7	-2.0	-1.9	-2.1	-1.5	-2.1	-1.9	-2.1
Smoking status: Current	0.6	1.0	2.3	-0.0	-1.2	-0.8	-1.5	-1.1	-0.7	-0.9	-0.7	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.3	-1.5	-0.5	-1.0	-0.8	-0.5	-0.6	-1.0	-0.4	-0.5
Alzheimer’s Disease (including proxy)	0.5	0.7	1.8	1.4	0.7	0.6	0.5	0.9	0.8	0.5	0.8	0.8
Crohns Disease (2012)	0.5	0.8	1.2	0.6	0.8	0.8	1.0	1.0	0.5	0.9	1.1	1.0
Lupus	0.5	0.8	1.8	0.2	-0.9	-1.1	-0.5	-0.6	-0.6	-1.3	-1.3	-0.8
Ulcerative Colitis	0.5	0.7	1.6	0.2	-0.7	-0.7	-0.9	-0.7	-0.9	-0.7	-1.3	-0.8
Sensitivity / hurt feelings	0.5	0.8	3.2	1.8	-0.9	-0.7	-0.9	-0.8	-0.5	-0.7	-0.1	-0.8
Relative age of first facial hair	0.5	1.0	1.4	-1.2	-1.2	-1.1	-1.1	-1.0	-1.2	-0.9	-0.4	-0.9
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	2.8	1.7	0.4	0.5	0.5	0.7	1.1	0.2	-0.2	0.4
Leg fat-free mass (left)	0.5	2.6	3.5	-0.6	-1.4	-1.7	-1.7	-1.8	-1.2	-1.9	-1.9	-1.8
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.9	1.4	-0.8	-0.5	-0.4	-0.5	-0.2	-0.7	-1.2	-0.7
Leg predicted mass (left)	0.5	2.8	3.8	-0.6	-1.5	-1.8	-1.7	-1.9	-1.3	-1.9	-1.9	-1.9
Medication: Paracetamol	0.5	0.8	1.3	-0.8	0.8	0.9	0.8	1.0	0.9	0.8	1.1	0.9
High blood pressure (siblings)	0.5	0.7	1.3	0.4	-0.7	-0.7	-0.9	-1.0	-1.1	-0.6	-0.4	-1.0
Emphysema/chronic bronchitis	0.5	0.5	2.4	1.6	-0.0	0.2	0.2	-0.1	-0.7	0.5	1.1	0.1
Medication for pain relief, constipation, heartburn	0.5	0.8	1.3	0.0	-1.2	-1.1	-0.7	-1.0	-0.9	-1.0	-1.0	-1.0
Family relationship satisfaction	0.5	0.6	1.0	1.0	0.6	0.7	0.4	0.8	0.4	0.9	0.9	1.0
Hearing aid user	0.5	0.6	2.1	-1.4	0.6	0.4	0.7	0.7	0.7	0.4	0.9	0.7
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.3	-0.2	-0.7	-0.7	-1.1	-0.8	-0.5	-0.8	-1.0	-1.0
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.3	1.5	-0.9	-0.6	-0.5	-0.4	-0.2	-0.8	-0.8	-0.6
Commuting to job workplace: Cycle	0.5	0.6	1.5	0.7	0.6	0.6	0.6	1.2	1.2	0.5	0.2	0.9
Blood Eosinophil Count	0.4	2.9	4.4	0.1	1.9	1.8	1.8	2.0	1.3	2.0	1.3	2.1
Supplements: Zinc	0.4	0.4	0.8	0.8	0.7	0.6	0.5	0.6	0.0	0.9	0.7	0.8
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.2	1.5	-0.7	-0.3	-0.6	-0.7	-0.8	-0.1	-0.6	-0.5
Mouth/teeth dental problems	0.4	0.7	1.5	0.8	0.5	1.0	0.9	1.0	1.2	0.7	0.4	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.9	1.7	-0.2	-0.4	-0.5	-0.6	-0.6	-0.3	-0.0	-0.5
Pulse wave peak to peak time	0.4	0.5	0.8	-0.7	-0.5	-0.8	-0.9	-0.8	-0.5	-0.8	0.1	-0.8
Had major operations	0.4	0.5	1.0	0.7	-0.7	-0.7	-1.0	-0.7	-0.9	-0.6	0.2	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.2	1.1	-0.5	-0.9	-0.7	-0.6	-0.7	-0.8	0.2	-0.6
Mood swings	0.4	0.7	2.2	1.5	0.8	0.8	0.8	0.8	1.0	0.7	0.0	0.7
Basal metabolic rate	0.4	2.3	3.5	-0.4	-1.3	-1.7	-1.5	-1.7	-1.2	-1.8	-1.9	-1.7
Supplements: Calcium	0.4	0.4	1.4	1.2	0.6	0.5	0.4	0.3	-0.1	0.7	0.7	0.5
Depressed Affect (Nagel 2018)	0.3	0.7	2.2	1.0	-0.7	-0.7	-0.7	-0.6	-0.2	-0.8	-1.5	-0.7
Alzheimer’s Disease (in father)	0.3	0.4	1.1	1.0	-0.5	-0.7	-0.5	-0.3	-0.3	-0.7	0.6	-0.4
Irritable Bowel Disease (IBD)	0.3	0.7	0.9	0.6	1.0	0.9	0.8	0.9	0.5	0.9	0.8	0.9
Verbal and Numeric Reasoning (VNR)	0.3	0.7	1.1	-0.0	-0.7	-0.9	-1.1	-1.1	-1.0	-0.9	-0.1	-1.0
Bipolar Disorder (2011)	0.3	0.3	0.7	0.9	-0.5	-0.6	-0.3	-0.6	-0.4	-0.7	0.0	-0.6
HbA1C	0.3	0.3	0.9	-0.8	-0.6	-0.4	-0.5	-0.3	-1.0	-0.2	-0.5	-0.1
Neuroticism (2016)	0.3	0.5	1.6	1.2	-0.5	-0.7	-0.7	-0.7	-0.6	-0.6	-0.0	-0.6
Respiratory disease	0.3	0.7	1.9	0.7	-0.5	-0.7	-0.4	-0.8	-1.3	-0.3	1.4	-0.6
Average weekly spirits intake	0.3	0.4	0.9	0.1	-0.5	-1.0	-0.3	-0.6	-0.8	-0.9	0.4	-0.6
Ever had hysterectomy (womb removed)	0.3	0.4	1.1	0.7	-0.6	-0.3	-0.6	-0.4	-0.3	-0.5	-1.0	-0.7
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.3	0.1	-0.4	-0.4	-0.5	-0.4	-0.4	-0.4	-1.2	-0.5
Medication: Co-codamol	0.3	0.4	2.0	-0.2	-0.6	-0.4	-0.5	-0.2	0.2	-0.7	-1.4	-0.4
Diabetes (father)	0.3	0.4	1.0	-0.3	0.8	0.2	0.4	0.8	1.0	0.1	-0.6	0.6
Current tobacco smoking	0.3	0.4	1.3	0.1	-0.9	-0.3	-1.1	-0.7	-0.3	-0.5	-0.6	-0.7
Fed-up feelings	0.3	0.6	2.0	1.4	0.3	0.1	0.0	0.4	1.0	-0.3	-1.3	0.1
Stomach or abdominal pain in last month	0.3	0.3	0.8	0.2	-0.5	-0.7	-0.7	-0.5	-0.9	-0.5	0.2	-0.4
Medication: Atenolol	0.3	0.4	2.1	-1.4	-0.5	-0.5	-0.5	-0.4	-0.6	-0.5	0.3	-0.4
Chronic bronchitis/emphysema (father)	0.3	0.3	0.6	0.5	-0.5	-0.5	-0.7	-0.5	-0.4	-0.6	-0.3	-0.6
Nervous feelings	0.3	0.5	0.9	0.1	0.8	0.7	0.5	0.7	0.6	0.9	1.0	0.9
Neuroticism score	0.3	0.7	1.9	1.4	0.8	0.8	0.5	0.7	0.9	0.8	0.7	0.7
Prospective memory result	0.3	0.4	2.3	1.5	0.1	0.6	0.5	0.3	0.1	0.6	-0.0	0.4
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.4	-0.8	0.6	0.1	0.3	0.3	-0.1	0.4	1.6	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	2.4	-1.6	0.3	0.2	0.0	0.2	0.4	0.1	-0.4	0.1
Average weekly red wine intake	0.3	0.4	0.9	-0.4	0.7	0.4	0.4	0.6	0.2	0.7	1.0	0.8
Qualifications: nursing, teaching	0.3	0.5	2.0	1.4	-0.4	-0.6	-0.3	-0.7	-1.0	-0.3	0.7	-0.5
Asthma (self-reported)	0.3	0.6	1.6	0.1	-0.7	-1.0	-0.5	-0.5	-1.0	-0.7	1.3	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	2.1	-1.4	-0.7	-0.7	-1.0	-0.6	-0.7	-0.6	-0.9	-0.6
Arm fat-free mass (left)	0.3	1.5	4.1	-0.4	-1.0	-1.2	-1.1	-1.3	-0.9	-1.3	-2.0	-1.4
Number of operations (self-reported)	0.3	0.5	1.7	0.6	-0.8	-0.6	-0.6	-0.8	-1.3	-0.3	0.0	-0.6
Ever depressed for a whole week	0.3	0.3	1.6	1.3	-0.3	0.1	-0.3	-0.5	-0.8	0.3	-0.3	-0.3
Arm predicted mass (left)	0.3	1.4	3.9	-0.3	-1.0	-1.2	-1.1	-1.3	-0.8	-1.3	-2.0	-1.3
Bipolar Disorder or Schizophrenia	0.2	0.5	3.0	1.7	0.5	0.3	0.6	0.3	0.3	0.4	0.3	0.4
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.3	1.1	-0.4	-0.7	-0.8	-0.7	-0.6	-0.7	-0.1	-0.7
Ovarian Cancer	0.2	0.2	0.6	0.7	-0.2	-0.6	-0.2	-0.4	-0.8	-0.4	0.1	-0.4
Schizophrenia (2014)	0.2	0.5	0.7	0.9	0.8	0.5	0.8	0.6	0.2	0.7	0.8	0.7
Allergy or Eczema	0.2	0.5	1.6	1.3	0.6	0.8	0.6	0.6	0.8	0.7	-0.0	0.6
Neuroticism	0.2	0.6	2.0	1.4	0.7	0.7	0.3	0.6	0.8	0.7	0.5	0.6
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.5	1.2	0.0	0.3	0.4	0.5	0.8	0.0	-0.3	0.2
Townsend deprivation index at recruitment	0.2	0.3	0.7	0.5	-0.1	-0.4	-0.7	-0.6	-0.8	-0.2	0.2	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.2	0.8	0.9	0.7	0.4	-0.0	0.2	0.1	0.6	0.5	0.4
Had menopause	0.2	0.3	1.7	1.3	0.1	0.2	-0.1	0.1	0.1	0.1	-0.7	-0.1
Forced vital capacity (FVC)	0.2	0.7	1.4	-1.2	0.9	0.6	0.5	0.5	-0.2	1.1	1.1	0.8
Time employed in main current job	0.2	0.2	0.5	0.5	-0.6	-0.7	-0.1	0.0	-0.5	-0.6	-0.2	0.0
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.3	0.8	0.5	0.3	0.7	0.3	0.0	0.5	1.1	0.5
Asthma	0.2	0.4	0.9	0.2	-0.6	-0.9	-0.5	-0.5	-0.9	-0.6	0.8	-0.3
Length of working week for main job	0.2	0.2	1.4	1.2	-0.4	-0.3	0.1	-0.0	0.1	-0.4	0.4	-0.1
Exposure to tobacco smoke at home	0.2	0.2	0.6	-0.8	-0.2	-0.4	-0.0	-0.1	0.4	-0.6	-0.4	-0.4
Medication: Seretide 50 evohaler	0.2	0.2	0.9	-1.0	-0.5	-0.3	-0.2	-0.3	-0.4	-0.3	0.4	-0.3
Arm predicted mass (right)	0.2	1.1	3.0	-0.4	-0.8	-1.1	-0.8	-1.1	-0.6	-1.2	-1.7	-1.2
Number of full sisters	0.2	0.3	1.9	-0.4	0.2	0.3	0.4	-0.0	-0.2	0.5	1.4	0.2
Long-standing illness, disability or infirmity	0.2	0.3	0.9	1.0	-0.2	-0.2	-0.8	-0.3	-0.4	-0.0	-0.6	-0.3
Ever had bowel cancer screening	0.2	0.2	1.3	1.2	0.2	0.1	0.2	-0.1	-0.4	0.2	0.2	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.2	1.1	0.3	0.0	0.4	0.1	0.3	-0.1	0.1	0.0
Commuting to job workplace: Walk	0.2	0.2	1.2	-1.1	0.2	0.2	-0.1	-0.1	-0.4	0.5	0.3	0.1
Medication: Gliclazide	0.2	0.2	0.5	0.7	-0.4	-0.3	-0.2	-0.2	0.3	-0.6	-0.7	-0.4
Whole body water mass	0.2	1.1	1.9	-0.5	-0.8	-1.1	-1.0	-1.2	-0.8	-1.1	-1.4	-1.2
Financial situation satisfaction	0.2	0.2	1.3	1.2	-0.1	-0.3	-0.2	-0.1	-0.4	-0.2	-0.6	-0.1
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.5	0.6	0.2	0.3	0.1	-0.2	-0.7	0.7	0.5	0.0
Illnesses of father: High blood pressure	0.2	0.2	1.8	-1.3	-0.1	-0.2	-0.2	-0.3	-0.4	-0.1	-0.1	-0.1
Risk taking	0.2	0.3	1.8	0.6	0.2	0.1	0.6	0.5	1.3	-0.4	-0.1	0.2
Age started oral contraceptive pill	0.2	0.2	0.4	-0.7	0.3	0.5	0.5	0.4	0.5	0.4	-0.4	0.3
Myopia	0.2	0.4	1.4	0.5	0.1	0.3	0.4	0.5	1.2	-0.2	-1.1	0.1
Neuroticism (Nagel 2018)	0.1	0.3	2.0	1.4	-0.0	-0.3	-0.3	0.1	0.1	-0.3	-0.3	-0.0
Mean Putamen Volume	0.1	0.1	0.1	0.2	0.0	-0.3	-0.2	-0.3	-0.3	-0.3	0.3	-0.2
Fasting Glucose	0.1	0.2	0.4	-0.5	0.6	0.4	0.5	0.0	0.0	0.6	0.2	0.1
LDL Cholesterol	0.1	0.1	0.5	-0.2	-0.1	-0.4	-0.3	-0.4	-0.7	-0.1	-0.3	-0.1
Blood White Count	0.1	0.8	1.6	1.0	-0.9	-0.6	-1.1	-0.5	0.2	-1.0	-1.3	-0.8
Waist Hip Ratio (WHR)	0.1	0.7	1.3	0.3	1.0	0.9	0.7	0.8	1.1	0.8	0.7	0.8
Lung FEV1/FVC ratio	0.1	0.6	3.2	0.7	-0.4	-0.3	-0.1	-0.2	0.8	-0.8	-1.8	-0.5
Lung FVC	0.1	0.5	2.2	-1.5	-0.2	-0.2	-0.7	-0.4	-1.0	0.1	-0.6	-0.2
Severe depression (siblings)	0.1	0.1	0.3	0.5	-0.2	-0.4	-0.3	-0.1	-0.0	-0.5	0.4	-0.1
Taking other prescription medications	0.1	0.1	0.2	-0.0	-0.4	-0.4	0.0	-0.2	-0.1	-0.5	-0.4	-0.2
Qualifications: CSEs or equivalent	0.1	0.1	0.2	-0.4	0.4	0.1	0.3	0.2	-0.4	0.5	0.4	0.4
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.3	0.5	-0.4	-0.3	-0.2	-0.4	-0.3	-0.3	0.2	-0.4
Financial difficulties in last 2 years	0.1	0.2	0.4	0.6	0.2	0.2	0.4	0.5	0.5	0.2	-0.0	0.5
Allergy	0.1	0.2	0.4	-0.3	0.4	0.6	0.5	0.5	0.6	0.4	0.1	0.4
Fluid intelligence score	0.1	0.2	0.9	0.9	0.1	-0.2	-0.6	-0.4	-0.2	-0.2	-0.3	-0.3
Illnesses of siblings	0.1	0.1	0.2	-0.4	0.0	0.1	0.5	0.4	0.4	0.0	-0.1	0.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.2	-1.1	0.8	0.5	0.5	0.5	0.2	0.7	0.4	0.7
Noisy workplace	0.1	0.2	0.9	0.5	-0.1	-0.1	-0.4	-0.3	0.0	-0.3	-0.9	-0.4
Pulse wave reflection index	0.1	0.1	0.6	-0.8	-0.2	-0.0	0.3	0.1	-0.3	0.1	-0.3	0.3
Headache pain in last month	0.1	0.2	0.4	-0.0	0.5	0.2	0.7	0.4	0.5	0.3	0.2	0.5
Arm fat-free mass (right)	0.1	0.7	2.2	-0.4	-0.6	-0.9	-0.6	-0.9	-0.5	-0.9	-1.5	-0.9
Number of full brothers	0.1	0.2	0.3	0.5	-0.2	0.1	-0.4	-0.4	-0.5	0.2	-0.5	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.3	0.6	-0.4	-0.4	-0.1	-0.3	-0.1	-0.5	-0.3	-0.4
Illnesses of siblings: Diabetes	0.1	0.2	0.7	-0.8	0.7	0.2	0.0	0.2	0.1	0.3	0.4	0.2
Whole body fat-free mass	0.1	0.8	1.5	-0.4	-0.6	-0.9	-0.8	-1.1	-0.7	-1.0	-1.2	-1.0
Friendships satisfaction	0.1	0.1	0.4	-0.2	0.3	0.4	0.2	0.4	-0.1	0.6	-0.1	0.5
Back pain experienced in last month	0.1	0.1	0.4	0.2	0.6	0.3	0.3	0.2	0.1	0.2	-0.3	0.1
Mineral and other dietary supplements	0.1	0.2	0.5	-0.7	-0.3	-0.4	-0.6	-0.1	0.3	-0.7	-0.1	-0.3
Number of self-reported non-cancer illnesses	0.1	0.1	0.9	0.9	-0.1	-0.2	0.1	-0.0	-0.3	-0.1	0.0	0.0
Guilty feelings	0.1	0.2	0.7	0.8	0.2	0.3	-0.0	-0.1	-0.3	0.5	-0.8	-0.0
Wears glasses or contact lenses	0.1	0.1	0.3	0.5	-0.2	0.1	-0.5	0.0	-0.1	0.1	-0.6	-0.0
Medication: Paracetamol	0.1	0.1	0.4	-0.1	-0.0	0.2	0.1	0.3	0.7	-0.1	0.4	0.1
Medication: Lisinopril	0.1	0.2	0.6	0.4	-0.4	-0.4	-0.0	-0.3	-0.8	-0.1	0.6	-0.1
Medication: Atorvastatin	0.1	0.2	1.0	1.0	0.0	-0.0	0.1	0.2	-0.2	0.2	0.6	0.3
Pain experienced in last month	0.1	0.2	0.5	-0.7	-0.3	0.4	-0.0	0.3	0.4	0.4	0.5	0.3
Ulcerative Colitis (UC)	0.0	0.1	0.2	-0.1	0.3	0.3	0.3	0.2	-0.1	0.4	0.2	0.3
Major Depression (MDD)	0.0	0.0	0.1	-0.1	-0.3	0.1	-0.4	0.0	0.2	-0.2	0.3	-0.2
HDL Cholesterol	0.0	0.1	0.3	-0.6	-0.0	0.1	-0.2	0.1	-0.1	0.2	0.2	0.1
Blood Red Count	0.0	0.4	2.2	-1.5	-0.1	-0.2	-0.4	-0.2	0.2	-0.3	-1.1	-0.4
Hair Pigment	0.0	1.3	2.6	0.9	-1.2	-1.2	-1.0	-1.1	-0.1	-1.6	-1.0	-1.4
Number of treatments/medications taken	0.0	0.1	0.3	0.5	-0.5	-0.3	-0.1	-0.1	-0.2	-0.3	-0.1	-0.2
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.2	0.4	0.1	0.2	0.2	0.0	0.4	0.2	-0.4	0.1
Trunk fat-free mass	0.0	0.1	0.3	-0.2	0.2	-0.1	-0.1	-0.3	-0.1	-0.1	-0.6	-0.2
Trunk predicted mass	0.0	0.1	0.3	-0.2	0.2	-0.1	-0.0	-0.3	-0.1	-0.1	-0.6	-0.2
Peak expiratory flow (PEF)	0.0	0.0	0.1	-0.1	0.2	-0.0	0.2	0.2	-0.0	0.1	-0.2	0.2
Miserableness	0.0	0.0	0.1	0.1	-0.1	0.1	-0.1	0.1	0.1	0.1	-0.4	0.1

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