Best TWAS P=7.04e-08 · Best GWAS P=4.23e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TMOD2 | 0.09 | 0.10 | enet | 8 | 0.10 | 3.0e-08 | -5.2 | -5.3 | 1.4e-07 | 0.99 | 0.04 | 0.96 | FALSE |
| 2 | GTEx | Muscle Skeletal | LYSMD2 | 0.23 | 0.23 | lasso | 4 | 0.21 | 1.6e-20 | -5.3 | 5.4 | 7.0e-08 | -0.97 | 0.03 | 0.97 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | TMOD3 | 0.05 | 0.07 | enet | 13 | 0.07 | 6.4e-05 | -5.5 | 5.1 | 3.1e-07 | -0.98 | 0.05 | 0.94 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | TMOD3 | 0.07 | 0.07 | enet | 22 | 0.06 | 6.0e-06 | -5.2 | 5.3 | 9.2e-08 | -0.99 | 0.03 | 0.97 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | TMOD2 | 0.02 | 0.01 | blup | 78 | 0.02 | 2.3e-03 | -4.6 | -5.2 | 2.5e-07 | 0.98 | 0.04 | 0.84 | FALSE |