[Hub]/) : Traits : Body mass index (BMI) :

chr17:39,993,748-41,538,783

Best TWAS P=7.49e-10 · Best GWAS P=5.72e-10 conditioned to 0.0458

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial RP11-400F19.6 0.07 0.01 lasso 5 0.01 3.0e-02 5.7 -5.8 9.2e-09 0.12 0.04 0.94 FALSE
2 GTEx Esophagus Mucosa TUBG2 0.09 0.09 lasso 4 0.11 5.5e-08 -4.3 -5.5 4.9e-08 0.12 0.18 0.82 FALSE
3 GTEx Esophagus Muscularis NAGLU 0.29 0.09 lasso 5 0.07 6.2e-05 5.2 -5.6 2.6e-08 0.16 0.31 0.58 FALSE
4 GTEx Esophagus Muscularis RP11-400F19.8 0.17 0.05 lasso 4 0.02 3.9e-02 5.2 -6.2 7.5e-10 0.24 0.06 0.18 TRUE
5 GTEx Pancreas CNTNAP1 0.13 0.09 lasso 7 0.09 9.1e-05 5.1 5.6 2.4e-08 -0.19 0.29 0.29 FALSE
6 GTEx Pancreas FAM134C 0.08 0.04 enet 9 0.03 2.0e-02 4.7 5.4 7.9e-08 -0.17 0.19 0.26 FALSE
7 GTEx Pancreas CTD-3193K9.3 0.12 0.07 lasso 5 0.07 5.7e-04 5.1 5.6 2.3e-08 -0.18 0.20 0.22 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic TUBG2 0.15 0.13 lasso 5 0.12 4.0e-07 5.7 -5.7 1.2e-08 0.10 0.03 0.97 FALSE
9 GTEx Stomach HSD17B1P1 0.10 0.04 lasso 3 0.04 6.9e-03 4.6 -5.2 1.6e-07 0.19 0.12 0.15 FALSE
10 GTEx Thyroid HSD17B1P1 0.04 0.00 enet 9 0.00 2.2e-01 -4.3 -5.5 3.7e-08 0.25 0.13 0.44 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma HSD17B1 0.30 0.05 enet 14 0.06 2.8e-07 -4.3 -5.4 6.1e-08 0.15 0.38 0.58 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma RND2 0.08 0.00 enet 16 0.02 3.5e-03 -4.4 5.3 1.4e-07 -0.61 0.00 0.07 TRUE
13 The Cancer Genome Atlas Lung Adenocarcinoma TUBG2 0.07 0.01 enet 7 0.02 2.2e-03 4.5 -5.2 2.6e-07 0.11 0.00 0.22 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PSMC3IP 0.02 0.02 blup 33 0.02 9.8e-04 -4.3 -5.3 9.9e-08 0.15 0.04 0.75 FALSE