[Hub]/) : Traits : Body mass index (BMI) :

chr17:65,123,352-66,844,411

Best TWAS P=7.88e-12 · Best GWAS P=9.43e-12 conditioned to 0.0643

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LINC00674 0.12 0.13 enet 6 0.14 9.9e-12 5.6 5.7 1.5e-08 0.79 0.90 0.10 FALSE
2 GTEx Adipose Subcutaneous SH3GL1P3 0.08 0.06 lasso 5 0.04 2.5e-04 5.6 5.5 3.9e-08 0.80 0.06 0.91 FALSE
3 GTEx Brain Cerebellum BPTF 0.22 -0.01 lasso 10 -0.01 6.9e-01 6.1 -6.2 6.6e-10 -0.85 0.03 0.48 FALSE
4 GTEx Brain Cortex C17orf58 0.34 0.09 lasso 6 0.13 2.4e-04 6.7 6.4 1.9e-10 0.95 0.03 0.95 FALSE
5 GTEx Cells Transformed fibroblasts LINC00674 0.30 0.31 enet 10 0.32 1.5e-24 5.6 6.2 5.3e-10 0.86 0.94 0.06 FALSE
6 GTEx Cells Transformed fibroblasts LRRC37A16P 0.50 0.46 lasso 8 0.47 1.1e-38 5.6 5.8 7.1e-09 0.84 0.94 0.06 FALSE
7 GTEx Cells Transformed fibroblasts SH3GL1P3 0.26 0.31 lasso 7 0.31 1.5e-23 5.6 6.2 5.6e-10 0.90 0.93 0.07 FALSE
8 GTEx Colon Sigmoid LINC00674 0.42 0.09 lasso 8 0.12 5.5e-05 6.1 5.7 1.5e-08 0.80 0.13 0.69 FALSE
9 GTEx Esophagus Muscularis LINC00674 0.11 0.04 lasso 6 0.07 7.9e-05 3.9 5.8 4.8e-09 0.77 0.18 0.80 FALSE
10 GTEx Heart Atrial Appendage LINC00674 0.14 0.08 lasso 17 0.09 1.1e-04 3.9 5.5 4.0e-08 0.73 0.05 0.87 FALSE
11 GTEx Lung LINC00674 0.14 0.03 enet 22 0.08 2.1e-06 6.5 5.2 1.7e-07 0.80 0.12 0.88 FALSE
12 GTEx Nerve Tibial LRRC37A16P 0.09 0.08 lasso 4 0.06 2.7e-05 5.7 5.7 1.1e-08 0.84 0.11 0.77 FALSE
13 YFS Blood KPNA2 0.01 0.01 blup 312 0.01 2.8e-04 6.1 -6.8 7.9e-12 -0.86 0.05 0.93 TRUE
14 The Cancer Genome Atlas Thyroid Carcinoma C17orf58 0.02 0.02 lasso 2 0.01 1.8e-02 6.7 6.7 2.1e-11 1.00 0.00 0.76 FALSE