Best TWAS P=2.11e-13 · Best GWAS P=1.67e-14 conditioned to 0.349
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | BAIAP2 | 0.36 | 0.01 | enet | 22 | 0.02 | 8.5e-02 | 3.7 | -7.3 | 2.1e-13 | 0.43 | 0.04 | 0.14 | TRUE |
| 2 | GTEx | Lung | CBX8 | 0.28 | 0.19 | enet | 24 | 0.18 | 1.4e-13 | -5.3 | 5.2 | 2.0e-07 | 0.12 | 0.00 | 1.00 | TRUE |
| 3 | GTEx | Muscle Skeletal | RPTOR | 0.14 | 0.05 | enet | 27 | 0.09 | 8.4e-09 | -6.1 | -7.3 | 3.1e-13 | 0.62 | 0.56 | 0.43 | TRUE |
| 4 | GTEx | Muscle Skeletal | CTD-2561B21.4 | 0.06 | 0.04 | lasso | 7 | 0.03 | 2.3e-04 | -6.0 | -6.7 | 1.7e-11 | 0.64 | 0.15 | 0.78 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | CTD-2561B21.4 | 0.10 | 0.09 | enet | 8 | 0.10 | 2.6e-08 | -3.2 | 5.1 | 2.9e-07 | -0.78 | 0.07 | 0.93 | FALSE |