[Hub]/) : Traits : Body mass index (BMI) :

chr20:24,230,055-26,182,690

Best TWAS P=2.72e-14 · Best GWAS P=4.85e-10 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ABHD12 0.10 0.17 blup 405 0.17 1.7e-20 4.9 6.2 7.4e-10 -0.19 0.71 0.29 FALSE
2 CommonMind Brain Pre-frontal Cortex NINL 0.19 0.17 lasso 20 0.23 1.2e-27 4.9 6.3 3.7e-10 -0.16 0.62 0.38 FALSE
3 GTEx Adipose Visceral Omentum ABHD12 0.06 0.00 lasso 8 0.00 4.6e-01 4.9 5.3 1.3e-07 -0.14 0.22 0.11 FALSE
4 GTEx Artery Aorta NINL 0.17 0.18 lasso 6 0.19 1.5e-10 4.9 5.6 2.2e-08 -0.15 0.64 0.36 FALSE
5 GTEx Brain Cerebellar Hemisphere ACSS1 0.31 0.24 lasso 3 0.16 7.1e-05 -4.9 -5.3 9.1e-08 0.23 0.18 0.12 TRUE
6 GTEx Breast Mammary Tissue ABHD12 0.08 0.09 lasso 5 0.09 3.3e-05 4.9 5.3 1.3e-07 -0.14 0.51 0.30 FALSE
7 GTEx Breast Mammary Tissue (Male) CST7 0.15 0.00 lasso 4 0.03 7.0e-02 -4.3 -5.3 9.8e-08 0.62 0.06 0.07 FALSE
8 GTEx Breast Mammary Tissue (Male) ABHD12 0.06 0.01 lasso 3 0.02 1.3e-01 4.6 5.5 4.4e-08 -0.13 0.05 0.17 FALSE
9 GTEx Heart Left Ventricle ABHD12 0.15 0.14 lasso 10 0.12 4.0e-07 5.0 5.3 9.1e-08 -0.18 0.66 0.34 FALSE
10 GTEx Lung ABHD12 0.06 0.00 lasso 6 0.00 2.7e-01 5.6 6.0 2.2e-09 -0.12 0.07 0.79 FALSE
11 GTEx Pancreas ENTPD6 0.11 0.05 enet 23 0.05 5.0e-03 5.6 -5.7 1.2e-08 0.15 0.16 0.74 FALSE
12 GTEx Pituitary ABHD12 0.27 0.31 enet 25 0.31 1.8e-08 4.8 5.6 1.9e-08 -0.14 0.71 0.29 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic PYGB 0.12 0.13 enet 13 0.14 4.2e-08 4.2 -5.1 2.8e-07 0.28 0.61 0.22 FALSE
14 GTEx Skin Sun Exposed Lower leg ABHD12 0.07 0.03 lasso 10 0.05 7.3e-05 4.7 5.6 1.6e-08 -0.19 0.66 0.25 FALSE
15 GTEx Testis ABHD12 0.21 0.18 enet 25 0.23 1.1e-10 4.9 5.3 9.3e-08 -0.14 0.68 0.32 FALSE
16 ROSMAP Brain Pre-frontal Cortex PYGB 0.20 0.10 bslmm 414 0.11 3.2e-14 5.6 -5.3 1.1e-07 0.07 0.08 0.92 FALSE
17 ROSMAP Brain Pre-frontal Cortex ABHD12 0.26 0.35 enet 35 0.42 7.9e-58 4.7 5.4 6.2e-08 -0.14 0.72 0.27 FALSE
18 ROSMAP Brain Pre-frontal Cortex APMAP 0.09 0.12 lasso 6 0.12 3.5e-15 -5.1 5.3 1.3e-07 -0.18 0.34 0.66 FALSE
19 ROSMAP Brain Pre-frontal Cortex ENTPD6 0.32 0.10 bslmm 432 0.12 1.8e-15 5.6 7.6 2.7e-14 -0.70 0.03 0.97 TRUE
20 YFS Blood ABHD12 0.15 0.35 bslmm 390 0.34 2.2e-118 5.0 5.2 1.8e-07 -0.16 0.65 0.35 TRUE
21 YFS Blood NINL 0.04 0.03 lasso 8 0.03 2.8e-10 5.4 5.2 1.9e-07 -0.07 0.17 0.83 FALSE
22 The Cancer Genome Atlas Breast Invasive Carcinoma PYGB 0.08 0.02 enet 7 0.03 1.7e-07 5.3 -5.4 7.8e-08 0.06 0.21 0.78 TRUE
23 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma PYGB 0.08 0.04 blup 74 0.06 1.0e-03 4.7 -5.3 9.9e-08 0.14 0.20 0.27 TRUE
24 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ABHD12 0.03 0.01 blup 77 0.01 8.7e-03 4.0 5.1 3.0e-07 -0.14 0.06 0.74 FALSE
25 The Cancer Genome Atlas Thyroid Carcinoma PYGB 0.10 0.08 lasso 7 0.07 1.4e-07 4.5 -5.4 7.4e-08 0.10 0.32 0.68 FALSE