[Hub]/) : Traits : Body mass index (BMI) : ← →

chr20:24,230,055-26,182,690

Best TWAS P=2.72e-14 · Best GWAS P=4.85e-10 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
19	ROSMAP	Brain Pre-frontal Cortex	ENTPD6	0.32	0.10	bslmm	432	0.12	1.8e-15	5.6	7.6	2.7e-14	-0.70	0.03	0.97	TRUE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	PYGB	0.08	0.02	enet	7	0.03	1.7e-07	5.3	-5.4	7.8e-08	0.06	0.21	0.78	TRUE
5	GTEx	Brain Cerebellar Hemisphere	ACSS1	0.31	0.24	lasso	3	0.16	7.1e-05	-4.9	-5.3	9.1e-08	0.23	0.18	0.12	TRUE
23	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	PYGB	0.08	0.04	blup	74	0.06	1.0e-03	4.7	-5.3	9.9e-08	0.14	0.20	0.27	TRUE
20	YFS	Blood	ABHD12	0.15	0.35	bslmm	390	0.34	2.2e-118	5.0	5.2	1.8e-07	-0.16	0.65	0.35	TRUE
2	CommonMind	Brain Pre-frontal Cortex	NINL	0.19	0.17	lasso	20	0.23	1.2e-27	4.9	6.3	3.7e-10	-0.16	0.62	0.38	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ABHD12	0.10	0.17	blup	405	0.17	1.7e-20	4.9	6.2	7.4e-10	-0.19	0.71	0.29	FALSE
10	GTEx	Lung	ABHD12	0.06	0.00	lasso	6	0.00	2.7e-01	5.6	6.0	2.2e-09	-0.12	0.07	0.79	FALSE
11	GTEx	Pancreas	ENTPD6	0.11	0.05	enet	23	0.05	5.0e-03	5.6	-5.7	1.2e-08	0.15	0.16	0.74	FALSE
14	GTEx	Skin Sun Exposed Lower leg	ABHD12	0.07	0.03	lasso	10	0.05	7.3e-05	4.7	5.6	1.6e-08	-0.19	0.66	0.25	FALSE
12	GTEx	Pituitary	ABHD12	0.27	0.31	enet	25	0.31	1.8e-08	4.8	5.6	1.9e-08	-0.14	0.71	0.29	FALSE
4	GTEx	Artery Aorta	NINL	0.17	0.18	lasso	6	0.19	1.5e-10	4.9	5.6	2.2e-08	-0.15	0.64	0.36	FALSE
8	GTEx	Breast Mammary Tissue (Male)	ABHD12	0.06	0.01	lasso	3	0.02	1.3e-01	4.6	5.5	4.4e-08	-0.13	0.05	0.17	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	ABHD12	0.26	0.35	enet	35	0.42	7.9e-58	4.7	5.4	6.2e-08	-0.14	0.72	0.27	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	PYGB	0.10	0.08	lasso	7	0.07	1.4e-07	4.5	-5.4	7.4e-08	0.10	0.32	0.68	FALSE
9	GTEx	Heart Left Ventricle	ABHD12	0.15	0.14	lasso	10	0.12	4.0e-07	5.0	5.3	9.1e-08	-0.18	0.66	0.34	FALSE
15	GTEx	Testis	ABHD12	0.21	0.18	enet	25	0.23	1.1e-10	4.9	5.3	9.3e-08	-0.14	0.68	0.32	FALSE
7	GTEx	Breast Mammary Tissue (Male)	CST7	0.15	0.00	lasso	4	0.03	7.0e-02	-4.3	-5.3	9.8e-08	0.62	0.06	0.07	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	PYGB	0.20	0.10	bslmm	414	0.11	3.2e-14	5.6	-5.3	1.1e-07	0.07	0.08	0.92	FALSE
3	GTEx	Adipose Visceral Omentum	ABHD12	0.06	0.00	lasso	8	0.00	4.6e-01	4.9	5.3	1.3e-07	-0.14	0.22	0.11	FALSE
6	GTEx	Breast Mammary Tissue	ABHD12	0.08	0.09	lasso	5	0.09	3.3e-05	4.9	5.3	1.3e-07	-0.14	0.51	0.30	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	APMAP	0.09	0.12	lasso	6	0.12	3.5e-15	-5.1	5.3	1.3e-07	-0.18	0.34	0.66	FALSE
21	YFS	Blood	NINL	0.04	0.03	lasso	8	0.03	2.8e-10	5.4	5.2	1.9e-07	-0.07	0.17	0.83	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	PYGB	0.12	0.13	enet	13	0.14	4.2e-08	4.2	-5.1	2.8e-07	0.28	0.61	0.22	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ABHD12	0.03	0.01	blup	77	0.01	8.7e-03	4.0	5.1	3.0e-07	-0.14	0.06	0.74	FALSE