Best TWAS P=1.24e-13 · Best GWAS P=3.82e-19 conditioned to 4.01e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3 | GTEx | Nerve Tibial | R3HCC1L | 0.06 | 0.07 | enet | 8 | 0.05 | 1.1e-04 | -7.02 | -7.4 | 1.2e-13 | 0.37 | 0.78 | 0.01 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | GOLGA7B | 0.07 | 0.00 | enet | 23 | 0.04 | 1.3e-05 | -0.36 | -6.3 | 2.3e-10 | 0.46 | 0.59 | 0.04 | TRUE |
| 1 | CommonMind | Brain Pre-frontal Cortex | CRTAC1 | 0.06 | 0.04 | lasso | 2 | 0.05 | 3.6e-07 | 4.39 | -7.1 | 1.3e-12 | 0.63 | 0.44 | 0.54 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | R3HCC1L | 0.10 | 0.05 | enet | 14 | 0.05 | 3.4e-05 | 4.87 | -6.3 | 3.4e-10 | 0.32 | 0.94 | 0.01 | FALSE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | LOXL4 | 0.08 | 0.00 | blup | 51 | 0.02 | 9.4e-03 | -4.27 | -6.2 | 5.5e-10 | 0.16 | 0.01 | 0.45 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LOXL4 | 0.09 | 0.05 | enet | 12 | 0.05 | 3.0e-06 | 4.88 | -5.3 | 1.1e-07 | 0.17 | 0.57 | 0.27 | FALSE |