Best TWAS P=1.42e-13 · Best GWAS P=1.84e-15 conditioned to 0.0177
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NEBL | 0.07 | 0.01 | blup | 662 | 0.03 | 9.7e-05 | -4.2 | -5.8 | 8.2e-09 | -0.03 | 0.76 | 0.01 | TRUE |
| 2 | GTEx | Artery Tibial | CASC10 | 0.05 | 0.06 | lasso | 4 | 0.02 | 1.3e-02 | 4.0 | 5.7 | 1.3e-08 | 0.52 | 0.26 | 0.46 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | MLLT10 | 0.06 | 0.02 | lasso | 4 | 0.03 | 8.0e-04 | 7.2 | -7.4 | 1.4e-13 | -0.94 | 0.02 | 0.98 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | CASC10 | 0.08 | 0.02 | lasso | 5 | 0.01 | 6.1e-02 | 5.6 | 6.6 | 5.7e-11 | 0.90 | 0.10 | 0.79 | FALSE |
| 5 | GTEx | Spleen | MLLT10 | 0.16 | 0.02 | lasso | 7 | 0.02 | 1.0e-01 | 5.6 | -6.6 | 4.1e-11 | -0.92 | 0.03 | 0.55 | FALSE |