Best TWAS P=1.38e-10 · Best GWAS P=1.25e-26 conditioned to 1.38e-17
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | SAE1 | 0.21 | 0.09 | lasso | 3 | 0.07 | 2.0e-03 | -4.4 | -6.3 | 2.1e-10 | 0.77 | 0.06 | 0.67 | FALSE |
| 2 | METSIM | Adipose | SAE1 | 0.12 | 0.04 | lasso | 5 | 0.07 | 1.7e-10 | -4.8 | -6.4 | 1.4e-10 | 0.61 | 0.61 | 0.39 | TRUE |
| 3 | YFS | Blood | SAE1 | 0.07 | 0.02 | enet | 18 | 0.05 | 3.6e-16 | -7.5 | -5.6 | 2.7e-08 | 0.56 | 0.99 | 0.01 | FALSE |