Best TWAS P=7.45e-09 · Best GWAS P=2.71e-23 conditioned to 9.68e-19
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | FOSB | 0.28 | 0.00 | lasso | 4 | 0.00 | 0.41300 | -4.0 | -5.2 | 2.4e-07 | 0.44 | 0.88 | 0.12 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | APOC1P1 | 0.05 | 0.03 | blup | 37 | 0.03 | 0.00052 | 1.9 | -5.8 | 7.4e-09 | -0.04 | 0.16 | 0.07 | TRUE |