Best TWAS P=6.53e-09 · Best GWAS P=3.43e-07 conditioned to 0.871
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | RASIP1 | 0.15 | 0.04 | lasso | 6 | 0.08 | 2.9e-05 | -4.8 | -5.8 | 6.5e-09 | 0.80 | 0.02 | 0.94 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | RASIP1 | 0.21 | 0.13 | enet | 19 | 0.17 | 1.1e-13 | 4.1 | -5.7 | 1.4e-08 | 0.89 | 0.02 | 0.97 | FALSE |
| 3 | GTEx | Spleen | PPFIA3 | 0.25 | 0.23 | lasso | 4 | 0.21 | 3.9e-06 | 4.6 | -5.4 | 8.3e-08 | 0.08 | 0.02 | 0.93 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | SNRNP70 | 0.05 | 0.02 | lasso | 3 | 0.02 | 2.9e-02 | 4.8 | -5.8 | 8.1e-09 | 0.06 | 0.01 | 0.58 | TRUE |