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chr21:45,583,922-46,988,606
Best TWAS P=8.29e-09 · Best GWAS P=1.92e-10 conditioned to 0.029
45.6M
45.8M
46M
46.2M
46.4M
46.6M
46.8M
47M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Muscle Skeletal
PTTG1IP
0.07
0.01
enet
6
0.00
9.7e-02
-6.2
5.8
8.3e-09
-0.71
0.01
0.88
TRUE
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
C21orf122
0.05
0.04
lasso
3
0.04
6.5e-05
5.5
-5.7
9.7e-09
0.60
0.01
0.98
TRUE
4
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
C21orf122
0.20
0.04
lasso
6
0.08
2.6e-04
5.5
-5.4
6.8e-08
0.57
0.01
0.94
FALSE
2
The Cancer Genome Atlas
Cervical Squamous Cell Carcinoma
ADARB1
0.07
0.01
blup
139
0.04
4.5e-03
5.0
-5.4
8.5e-08
0.83
0.02
0.88
FALSE