Best TWAS P=8.29e-09 · Best GWAS P=1.92e-10 conditioned to 0.029
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | PTTG1IP | 0.07 | 0.01 | enet | 6 | 0.00 | 9.7e-02 | -6.2 | 5.8 | 8.3e-09 | -0.71 | 0.01 | 0.88 | TRUE |
| 2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | ADARB1 | 0.07 | 0.01 | blup | 139 | 0.04 | 4.5e-03 | 5.0 | -5.4 | 8.5e-08 | 0.83 | 0.02 | 0.88 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | C21orf122 | 0.05 | 0.04 | lasso | 3 | 0.04 | 6.5e-05 | 5.5 | -5.7 | 9.7e-09 | 0.60 | 0.01 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | C21orf122 | 0.20 | 0.04 | lasso | 6 | 0.08 | 2.6e-04 | 5.5 | -5.4 | 6.8e-08 | 0.57 | 0.01 | 0.94 | FALSE |