Best TWAS P=3.4e-08 · Best GWAS P=7.09e-08 conditioned to 0.0731
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | BCL2L13 | 0.19 | 0.09 | lasso | 13 | 0.12 | 5.9e-15 | 5.4 | -5.3 | 1.1e-07 | -0.88 | 0.00 | 0.99 | FALSE |
2 | YFS | Blood | BCL2L13 | 0.08 | 0.07 | bslmm | 544 | 0.10 | 1.6e-30 | 4.9 | 5.5 | 3.4e-08 | 0.77 | 0.01 | 0.98 | TRUE |
3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | BID | 0.16 | -0.01 | blup | 70 | 0.06 | 5.1e-03 | 4.8 | -5.3 | 1.4e-07 | -0.75 | 0.00 | 0.91 | FALSE |