Best TWAS P=4.88e-12 · Best GWAS P=7.42e-11 conditioned to 0.192
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | AFF3 | 0.14 | 0.06 | lasso | 5 | 0.07 | 1.2e-04 | -6.5 | -6.9 | 4.9e-12 | 0.84 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Thyroid | CHST10 | 0.05 | 0.05 | lasso | 5 | 0.03 | 2.6e-03 | -4.0 | -5.1 | 2.9e-07 | 0.60 | 0.39 | 0.40 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LONRF2 | 0.06 | 0.04 | blup | 69 | 0.04 | 3.4e-05 | 3.8 | -5.3 | 9.5e-08 | 0.68 | 0.59 | 0.39 | FALSE |