Best TWAS P=2.81e-10 · Best GWAS P=3.28e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | LUZP1 | 0.23 | 0.14 | lasso | 5 | 0.10 | 7.8e-04 | -5.5 | 5.6 | 2.7e-08 | -0.63 | 0.05 | 0.46 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | LUZP1 | 0.09 | 0.09 | lasso | 4 | 0.08 | 2.8e-06 | -5.5 | 5.5 | 3.6e-08 | -0.63 | 0.25 | 0.73 | FALSE |
| 3 | GTEx | Testis | LUZP1 | 0.17 | 0.09 | lasso | 4 | 0.08 | 2.6e-04 | -6.1 | -5.5 | 4.1e-08 | 0.94 | 0.01 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | HTR1D | 0.24 | 0.12 | lasso | 4 | 0.12 | 1.2e-05 | -6.2 | 6.3 | 2.8e-10 | -0.97 | 0.00 | 1.00 | TRUE |