[Hub]/) : Traits : Weight : ← →

chr4:47,802,595-53,598,975

Best TWAS P=6.73e-11 · Best GWAS P=1.05e-11 conditioned to 0.0241

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SGCB 0.02 0.02 enet 21 0.01 9.7e-03 5.5 5.3 9.1e-08 0.69 0.05 0.84 FALSE
2 GTEx Adrenal Gland OCIAD1 0.10 -0.01 enet 11 0.02 5.5e-02 -4.6 -5.3 1.2e-07 -0.39 0.15 0.08 FALSE
3 GTEx Breast Mammary Tissue DCUN1D4 0.08 0.02 enet 11 0.04 2.4e-03 6.5 6.3 2.8e-10 0.89 0.04 0.89 FALSE
4 GTEx Breast Mammary Tissue (Female) DCUN1D4 0.02 0.03 lasso 1 0.02 8.2e-02 6.5 6.5 6.9e-11 0.96 0.02 0.20 FALSE
5 GTEx Cells Transformed fibroblasts DCUN1D4 0.05 0.04 enet 15 0.04 7.8e-04 6.0 5.9 3.3e-09 0.85 0.06 0.89 FALSE
6 GTEx Colon Transverse OCIAD1 0.07 0.07 lasso 5 0.05 2.8e-03 5.3 -5.2 1.7e-07 -0.44 0.40 0.27 FALSE
7 GTEx Esophagus Muscularis OCIAD1 0.12 0.16 lasso 6 0.17 9.1e-11 5.3 -5.3 8.9e-08 -0.46 0.87 0.13 FALSE
8 GTEx Heart Atrial Appendage LRRC66 0.06 0.02 lasso 3 0.01 7.9e-02 6.2 5.1 2.8e-07 0.65 0.07 0.66 FALSE
9 GTEx Nerve Tibial DCUN1D4 0.10 0.09 lasso 3 0.10 6.8e-08 6.0 6.5 9.4e-11 0.93 0.08 0.92 FALSE
10 GTEx Ovary FRYL 0.12 -0.01 enet 21 0.03 7.2e-02 5.5 6.0 2.4e-09 0.62 0.07 0.49 FALSE
11 GTEx Testis DCUN1D4 0.19 0.17 enet 14 0.16 8.7e-08 6.2 6.3 3.1e-10 0.84 0.09 0.91 FALSE
12 GTEx Thyroid DCUN1D4 0.03 0.05 lasso 1 0.04 2.4e-04 6.5 6.5 6.9e-11 0.96 0.04 0.93 FALSE
13 ROSMAP Brain Pre-frontal Cortex SGCB 0.03 0.03 enet 9 0.03 7.0e-05 6.3 6.5 6.7e-11 0.87 0.05 0.95 TRUE
14 The Cancer Genome Atlas Colon Adenocarcinoma LRRC66 0.07 0.03 lasso 3 0.05 8.0e-04 5.8 -6.0 2.0e-09 -0.62 0.03 0.37 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma FRYL 0.02 0.01 blup 93 0.01 3.6e-02 5.2 5.4 7.7e-08 0.49 0.03 0.74 FALSE