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chr4:47,802,595-53,598,975

Best TWAS P=6.73e-11 · Best GWAS P=1.05e-11 conditioned to 0.0241

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
13	ROSMAP	Brain Pre-frontal Cortex	SGCB	0.03	0.03	enet	9	0.03	7.0e-05	6.3	6.5	6.7e-11	0.87	0.05	0.95	TRUE
4	GTEx	Breast Mammary Tissue (Female)	DCUN1D4	0.02	0.03	lasso	1	0.02	8.2e-02	6.5	6.5	6.9e-11	0.96	0.02	0.20	FALSE
12	GTEx	Thyroid	DCUN1D4	0.03	0.05	lasso	1	0.04	2.4e-04	6.5	6.5	6.9e-11	0.96	0.04	0.93	FALSE
9	GTEx	Nerve Tibial	DCUN1D4	0.10	0.09	lasso	3	0.10	6.8e-08	6.0	6.5	9.4e-11	0.93	0.08	0.92	FALSE
3	GTEx	Breast Mammary Tissue	DCUN1D4	0.08	0.02	enet	11	0.04	2.4e-03	6.5	6.3	2.8e-10	0.89	0.04	0.89	FALSE
11	GTEx	Testis	DCUN1D4	0.19	0.17	enet	14	0.16	8.7e-08	6.2	6.3	3.1e-10	0.84	0.09	0.91	FALSE
14	The Cancer Genome Atlas	Colon Adenocarcinoma	LRRC66	0.07	0.03	lasso	3	0.05	8.0e-04	5.8	-6.0	2.0e-09	-0.62	0.03	0.37	FALSE
10	GTEx	Ovary	FRYL	0.12	-0.01	enet	21	0.03	7.2e-02	5.5	6.0	2.4e-09	0.62	0.07	0.49	FALSE
5	GTEx	Cells Transformed fibroblasts	DCUN1D4	0.05	0.04	enet	15	0.04	7.8e-04	6.0	5.9	3.3e-09	0.85	0.06	0.89	FALSE
15	The Cancer Genome Atlas	Thyroid Carcinoma	FRYL	0.02	0.01	blup	93	0.01	3.6e-02	5.2	5.4	7.7e-08	0.49	0.03	0.74	FALSE
7	GTEx	Esophagus Muscularis	OCIAD1	0.12	0.16	lasso	6	0.17	9.1e-11	5.3	-5.3	8.9e-08	-0.46	0.87	0.13	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SGCB	0.02	0.02	enet	21	0.01	9.7e-03	5.5	5.3	9.1e-08	0.69	0.05	0.84	FALSE
2	GTEx	Adrenal Gland	OCIAD1	0.10	-0.01	enet	11	0.02	5.5e-02	-4.6	-5.3	1.2e-07	-0.39	0.15	0.08	FALSE
6	GTEx	Colon Transverse	OCIAD1	0.07	0.07	lasso	5	0.05	2.8e-03	5.3	-5.2	1.7e-07	-0.44	0.40	0.27	FALSE
8	GTEx	Heart Atrial Appendage	LRRC66	0.06	0.02	lasso	3	0.01	7.9e-02	6.2	5.1	2.8e-07	0.65	0.07	0.66	FALSE