TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Weight
:
←
→
chr4:105,598,022-107,092,169
Best TWAS P=7.65e-10 · Best GWAS P=1.02e-10 conditioned to 0.0122
105.6M
105.8M
106M
106.2M
106.4M
106.6M
106.8M
107M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Esophagus Gastroesophageal Junction
PPA2
0.29
0.15
lasso
5
0.14
8.8e-06
-6.1
-6.2
7.7e-10
0.81
0.03
0.94
TRUE
3
GTEx
Esophagus Mucosa
PPA2
0.18
0.06
enet
14
0.12
2.5e-08
5.5
-6.0
1.4e-09
0.68
0.08
0.91
FALSE
4
GTEx
Ovary
PPA2
0.18
0.10
lasso
3
0.14
2.2e-04
-4.6
-5.9
4.1e-09
0.72
0.05
0.71
FALSE
1
GTEx
Brain Cortex
PPA2
0.14
0.09
lasso
9
0.09
1.6e-03
-5.1
-5.1
2.8e-07
0.79
0.05
0.62
FALSE