Best TWAS P=7.65e-10 · Best GWAS P=1.02e-10 conditioned to 0.0122
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | PPA2 | 0.14 | 0.09 | lasso | 9 | 0.09 | 1.6e-03 | -5.1 | -5.1 | 2.8e-07 | 0.79 | 0.05 | 0.62 | FALSE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | PPA2 | 0.29 | 0.15 | lasso | 5 | 0.14 | 8.8e-06 | -6.1 | -6.2 | 7.7e-10 | 0.81 | 0.03 | 0.94 | TRUE |
| 3 | GTEx | Esophagus Mucosa | PPA2 | 0.18 | 0.06 | enet | 14 | 0.12 | 2.5e-08 | 5.5 | -6.0 | 1.4e-09 | 0.68 | 0.08 | 0.91 | FALSE |
| 4 | GTEx | Ovary | PPA2 | 0.18 | 0.10 | lasso | 3 | 0.14 | 2.2e-04 | -4.6 | -5.9 | 4.1e-09 | 0.72 | 0.05 | 0.71 | FALSE |