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chr5:12,225-1,051,918

Best TWAS P=4e-09 · Best GWAS P=3.63e-08 conditioned to 0.629

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	YFS	Blood	PDCD6	0.03	0.03	bslmm	276	0.03	1.6e-09	5.5	5.9	4.0e-09	0.90	0.01	0.98	TRUE
6	GTEx	Thyroid	CTD-2083E4.5	0.07	0.06	lasso	2	0.04	3.6e-04	5.5	-5.6	1.8e-08	-0.99	0.01	0.98	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PDCD6	0.03	0.02	blup	49	0.02	2.9e-03	5.3	5.6	2.6e-08	0.95	0.02	0.96	FALSE
3	GTEx	Cells Transformed fibroblasts	SDHA	0.23	0.18	lasso	2	0.17	1.6e-12	5.5	5.5	3.9e-08	0.99	0.01	0.99	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	SDHA	0.06	0.09	lasso	13	0.08	1.8e-08	5.5	5.4	7.7e-08	0.99	0.01	0.99	FALSE
2	GTEx	Artery Aorta	PDCD6	0.26	0.17	lasso	4	0.14	2.8e-08	5.5	-5.3	1.0e-07	-0.98	0.01	0.99	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SDHA	0.04	0.03	blup	62	0.05	3.3e-06	5.5	5.3	1.0e-07	0.87	0.02	0.98	FALSE
4	GTEx	Cells Transformed fibroblasts	CTD-2083E4.5	0.09	0.07	lasso	3	0.05	1.2e-04	5.5	-5.3	1.1e-07	-1.00	0.01	0.98	FALSE
11	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LRRC14B	0.08	0.04	lasso	5	0.03	6.7e-03	5.3	5.3	1.1e-07	0.97	0.01	0.96	FALSE
12	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	AHRR	0.11	0.05	lasso	3	0.07	2.5e-04	5.5	5.3	1.1e-07	0.85	0.01	0.93	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	PDCD6	0.07	0.06	enet	5	0.07	2.0e-07	5.5	-5.3	1.2e-07	-0.91	0.01	0.99	FALSE
7	GTEx	Whole Blood	SDHA	0.05	0.01	lasso	5	0.01	3.4e-02	4.3	-5.2	1.5e-07	-0.90	0.02	0.92	FALSE
5	GTEx	Nerve Tibial	CCDC127	0.05	0.01	lasso	4	0.02	2.2e-02	4.3	5.2	1.8e-07	0.86	0.04	0.82	FALSE
1	GTEx	Adipose Subcutaneous	SDHA	0.10	0.09	lasso	5	0.07	1.9e-06	5.5	5.1	3.0e-07	0.97	0.01	0.99	FALSE