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chr5:76,597,461-78,753,539

Best TWAS P=2.78e-21 · Best GWAS P=9.1e-21 conditioned to 0.0192

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	The Cancer Genome Atlas	Breast Invasive Carcinoma	AP3B1	0.02	0.00	blup	126	0.01	1.8e-02	-9.2	-9.5	2.8e-21	0.86	0.02	0.91	TRUE
8	The Cancer Genome Atlas	Prostate Adenocarcinoma	AP3B1	0.05	0.02	blup	126	0.03	5.0e-04	7.5	-9.3	1.0e-20	0.80	0.02	0.91	FALSE
5	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	AP3B1	0.16	0.06	enet	18	0.09	2.2e-05	7.3	-7.5	8.6e-14	0.53	0.04	0.54	FALSE
3	YFS	Blood	AP3B1	0.25	0.22	lasso	9	0.23	2.6e-74	6.8	-7.1	1.6e-12	0.31	1.00	0.00	FALSE
6	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AP3B1	0.08	0.01	enet	20	0.02	9.7e-04	-9.0	-7.0	3.7e-12	0.58	0.02	0.80	FALSE
7	The Cancer Genome Atlas	Lung Adenocarcinoma	AP3B1	0.05	0.03	lasso	3	0.04	4.4e-05	7.3	-6.7	1.8e-11	0.36	0.41	0.28	FALSE
2	METSIM	Adipose	AP3B1	0.07	0.01	blup	556	0.02	2.4e-04	4.4	-6.6	4.1e-11	0.53	0.11	0.77	FALSE
9	The Cancer Genome Atlas	Thyroid Carcinoma	AP3B1	0.11	0.06	lasso	2	0.05	1.3e-05	6.8	-6.4	1.8e-10	0.20	0.59	0.06	FALSE
1	GTEx	Testis	LHFPL2	0.18	-0.01	enet	21	0.10	2.1e-05	2.8	5.5	4.1e-08	-0.25	0.11	0.15	FALSE